Imperial College London
Alternate

Professor Karen Polizzi

Faculty of Engineering, Department of Chemical Engineering

Professor of Biotechnology
 
 
 
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Contact

 

+44 (0)20 7594 2851k.polizzi

 
 
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Location

 

411ACE ExtensionSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Dekker:2017:10.1016/j.cbpa.2017.05.014,
author = {Dekker, L and Polizzi, KM},
doi = {10.1016/j.cbpa.2017.05.014},
journal = {Current Opinion in Chemical Biology},
pages = {31--36},
title = {Sense and sensitivity in bioprocessing-detecting cellular metabolites with biosensors.},
url = {http://dx.doi.org/10.1016/j.cbpa.2017.05.014},
volume = {40},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Biosensors use biological elements to detect or quantify an analyte of interest. In bioprocessing, biosensors are employed to monitor key metabolites. There are two main types: fully biological systems or biological recognition coupled with physical/chemical detection. New developments in chemical biosensors include multiplexed detection using microfluidics. Synthetic biology can be used to engineer new biological biosensors with improved characteristics. Although there have been few biosensors developed for bioprocessing thus far, emerging trends can be applied in the future. A range of new platform technologies will enable rapid engineering of new biosensors based on transcriptional activation, riboswitches, and Förster Resonance Energy Transfer. However, translation to industry remains a challenge and more research into the robustness biosensors at scale is needed.
AU  - Dekker,L
AU  - Polizzi,KM
DO  - 10.1016/j.cbpa.2017.05.014
EP  - 36
PY  - 2017///
SN  - 1367-5931
SP  - 31
TI  - Sense and sensitivity in bioprocessing-detecting cellular metabolites with biosensors.
T2  - Current Opinion in Chemical Biology
UR  - http://dx.doi.org/10.1016/j.cbpa.2017.05.014
UR  - https://www.ncbi.nlm.nih.gov/pubmed/28609710
UR  - http://hdl.handle.net/10044/1/49822
VL  - 40
ER  -
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