Summary
I am Senior Clinical Research Fellow in vaccinology and Honorary Consultant in genitourinary medicine at Imperial College London and Imperial College Healthcare NHS Trust. I read medicine at Newnham College, University of Cambridge, and Imperial College London before completing speciality training as a clinician scientist in genitourinary medicine and immunology. My research investigates diversity in T cell responses to accelerate discovery in vaccine design and implementation. I lead first-in-human trials and experimental medicine studies of novel vaccines against hard-to-target pathogens including HIV and chlamydia. I am Chief and Principal Investigator for the Imperial College London self amplifying RNA SARS-CoV-2 vaccine and Oxford Astra-Zeneca COVID-19 vaccine trials. I received a Department of Infectious Disease award for substantial and exceptional achievement during the COVID-19 pandemic.
Publications
Journals
Thwaites R, Uruchurtu ASS, Negri VA, et al. , 2023, Early mucosal events drive distinct mucosal and systemic antibody responses to live attenuated influenza vaccine, Nature Communications, Vol:14, ISSN:2041-1723
Liu Z, Alexander J, Eng K, et al. , 2023, Antibody responses to Influenza vaccination are diminished in patients with inflammatory bowel disease on infliximab or tofacitinib, Journal of Crohn's and Colitis, ISSN:1873-9946
Liu Z, Alexander J, Le K, et al. , 2023, Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study, Eclinicalmedicine, Vol:64, ISSN:2589-5370
Khan M, Bradshaw D, Brown CS, et al. , 2023, Characterization of rare spontaneous human immunodeficiency virus viral controllers attending a national United Kingdom clinical service using a combination of serology and molecular diagnostic assays, Open Forum Infectious Diseases, Vol:10, ISSN:2328-8957
Writing Committee for the REMAP-CAP Investigators, Lawler PR, Derde LPG, et al. , 2023, Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support–free days in patients hospitalized with COVID-19, Jama: Journal of the American Medical Association, Vol:329, ISSN:0098-7484, Pages:1183-1196