The group’s research interests cover a range of topics including eukaryotic protein folding and single molecule approaches to protein dynamics and protein counting. Everything we do involves interdisciplinary approaches to biological research problems – we collaborate with physicists, mathematicians and engineers across Imperial College. We are founder members of the Centre for Doctoral Training in Chemical Biology and the Institute of Chemical Biology.
Willison KR, 2018, The substrate specificity of eukaryotic cytosolic chaperonin CCT, Philosophical Transactions of the Royal Society B-biological Sciences, Vol:373, ISSN:0962-8436
et al., 2017, Multiplexed single cell protein expression analysis in solid tumours using a miniaturised microfluidic assay, Convergent Science Physical Oncology, Vol:3, Pages:024003-024003
et al., 2016, Plasmodium actin is incompletely folded by heterologous protein-folding machinery and likely requires the native Plasmodium chaperonin complex to enter a mature functional state, Faseb Journal, Vol:30, ISSN:0892-6638, Pages:405-416
et al., 2015, Absolute quantification of protein copy number in single cells using single molecule microarrays, European Biophysics Journal With Biophysics Letters, Vol:44, ISSN:0175-7571, Pages:S179-S179
et al., 2018, Probing Synaptic Amyloid-Beta Aggregation Promoted by Copper Release, 62nd Annual Meeting of the Biophysical-Society, CELL PRESS, Pages:430A-430A, ISSN:0006-3495