Imperial College London
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DrLorenzoDi Michele

Faculty of Natural Sciences, Department of Chemistry

Honorary Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 3262l.di-michele Website

 
 
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Location

 

Molecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Di:2016:10.1063/1.4947550,
author = {Di, Michele L and Bachmann, SJ and Parolini, L and Mognetti, BM},
doi = {10.1063/1.4947550},
journal = {Journal of Chemical Physics},
pages = {1--5},
title = {Communication: Free energy of ligand-receptor systems forming multimeric complexes},
url = {http://dx.doi.org/10.1063/1.4947550},
volume = {144},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Ligand-receptor interactions are ubiquitous in biology and have become popular in materials in view of their applications to programmable self-assembly. Although complex functionalities often emerge from the simultaneous interaction of more than just two linker molecules, state of the art theoretical frameworks enable the calculation of the free energy only in systems featuring one-to-one ligand/receptor binding. In this Communication, we derive a general formula to calculate the free energy of systems featuring simultaneous direct interaction between an arbitrary number of linkers. To exemplify the potential and generality of our approach, we apply it to the systems recently introduced by Parolini et al. [ACS Nano 10, 2392 (2016)] and Halverson and Tkachenko [J. Chem. Phys. 144, 094903 (2016)], both featuring functionalized Brownian particles interacting via three-linker complexes.
AU  - Di,Michele L
AU  - Bachmann,SJ
AU  - Parolini,L
AU  - Mognetti,BM
DO  - 10.1063/1.4947550
EP  - 5
PY  - 2016///
SN  - 0021-9606
SP  - 1
TI  - Communication: Free energy of ligand-receptor systems forming multimeric complexes
T2  - Journal of Chemical Physics
UR  - http://dx.doi.org/10.1063/1.4947550
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000375785800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://aip.scitation.org/doi/10.1063/1.4947550
UR  - http://hdl.handle.net/10044/1/92878
VL  - 144
ER  -
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