Imperial College London
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DrLorenzoDi Michele

Faculty of Natural Sciences, Department of Chemistry

Honorary Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 3262l.di-michele Website

 
 
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Location

 

Molecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Parolini:2015:10.1038/ncomms6948,
author = {Parolini, L and Mognetti, BM and Kotar, J and Eiser, E and Cicuta, P and Di, Michele L},
doi = {10.1038/ncomms6948},
journal = {Nature Communications},
pages = {1--10},
title = {Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranes},
url = {http://dx.doi.org/10.1038/ncomms6948},
volume = {6},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Short DNA linkers are increasingly being exploited for driving-specific self-assembly of Brownian objects. DNA-functionalized colloids can assemble into ordered or amorphous materials with tailored morphology. Recently, the same approach has been applied to compliant units, including emulsion droplets and lipid vesicles. The liquid structure of these substrates introduces new degrees of freedom: the tethers can diffuse and rearrange, radically changing the physics of the interactions. Unlike droplets, vesicles are extremely deformable and DNA-mediated adhesion causes significant shape adjustments. We investigate experimentally the thermal response of pairs and networks of DNA-tethered liposomes and observe two intriguing and possibly useful collective properties: negative thermal expansion and tuneable porosity of the liposome networks. A model providing a thorough understanding of this unexpected phenomenon is developed, explaining the emergent properties out of the interplay between the temperature-dependent deformability of the vesicles and the DNA-mediated adhesive forces.
AU  - Parolini,L
AU  - Mognetti,BM
AU  - Kotar,J
AU  - Eiser,E
AU  - Cicuta,P
AU  - Di,Michele L
DO  - 10.1038/ncomms6948
EP  - 10
PY  - 2015///
SN  - 2041-1723
SP  - 1
TI  - Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranes
T2  - Nature Communications
UR  - http://dx.doi.org/10.1038/ncomms6948
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000348810700004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.nature.com/articles/ncomms6948
VL  - 6
ER  -
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