Imperial College London
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ProfessorLesleyRegan

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Professor
 
 
 
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Contact

 

+44 (0)20 3312 1798l.regan

 
 
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Assistant

 

Ms Hazel Blackman +44 (0)20 7594 2104

 
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Location

 

MWG022Mint WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Quinn:2014:10.1016/j.ejogrb.2014.09.039,
author = {Quinn, SD and Vedelago, J and Gedroyc, W and Regan, L},
doi = {10.1016/j.ejogrb.2014.09.039},
journal = {Eur J Obstet Gynecol Reprod Biol},
pages = {247--251},
title = {Safety and five-year re-intervention following magnetic resonance-guided focused ultrasound (MRgFUS) for uterine fibroids.},
url = {http://dx.doi.org/10.1016/j.ejogrb.2014.09.039},
volume = {182},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVE: To examine the safety and re-intervention rates following magnetic resonance-guided focused ultrasound (MRgFUS) for uterine fibroids at 5 years. To assess how the non-perfused volume (NPV), fibroid signal intensity and use of gonadotrophin-releasing hormone analogues (GnRHa) affect the re-intervention rates. STUDY DESIGN: Cohort study of women undergoing MRgFUS for treatment of their uterine fibroids between 2003 and 2010. RESULTS: Of 280 women undergoing MRgFUS the rate of minor complications was 3.9% and there were 3 serious complications (1.1%) including one skin burn, a fibroid expulsion and one case of persistent neuropathy. The NPVs achieved following MRgFUS have increased as the experience with this treatment has grown. In a 5-year follow-up study of 162 women, the overall re-intervention rate was 58.64%, but in those treatments with greater than 50% NPV the re-intervention rate was 50%. CONCLUSION: MRgFUS treatment of uterine fibroids is a safe treatment for uterine fibroids. The re-intervention rate at 5 years is high, but the improvements in NPVs achieved may further improve the long term results.
AU  - Quinn,SD
AU  - Vedelago,J
AU  - Gedroyc,W
AU  - Regan,L
DO  - 10.1016/j.ejogrb.2014.09.039
EP  - 251
PY  - 2014///
SP  - 247
TI  - Safety and five-year re-intervention following magnetic resonance-guided focused ultrasound (MRgFUS) for uterine fibroids.
T2  - Eur J Obstet Gynecol Reprod Biol
UR  - http://dx.doi.org/10.1016/j.ejogrb.2014.09.039
UR  - https://www.ncbi.nlm.nih.gov/pubmed/25445107
VL  - 182
ER  -
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