Imperial College London
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ProfessorLesleyRegan

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Professor
 
 
 
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Contact

 

+44 (0)20 3312 1798l.regan

 
 
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Assistant

 

Ms Hazel Blackman +44 (0)20 7594 2104

 
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Location

 

MWG022Mint WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Leon:2016:10.1016/j.placenta.2016.08.085,
author = {Leon, LJ and Solanky, N and Stalman, SE and Demetriou, C and Abu-Amero, S and Stanier, P and Regan, L and Moore, GE},
doi = {10.1016/j.placenta.2016.08.085},
journal = {Placenta},
pages = {31--37},
title = {A new biological and clinical resource for research into pregnancy complications: The Baby Bio Bank},
url = {http://dx.doi.org/10.1016/j.placenta.2016.08.085},
volume = {46},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - About 20% of pregnancies are affected by some form of complication. Research has shown that anomalies in implantation, development, and growth of the fetus; ineffective nutrient exchange between mother and fetus due to placental dysfunction; and maternal problems such as hypertension or infection during pregnancy can all lead to adverse pregnancy outcomes. However, the molecular aetiology of such events remains poorly understood. Fetal growth restriction (FGR), recurrent miscarriage (RM), preterm birth (PTB), and pre-eclampsia (PE) are the most common pregnancy complications encountered in the UK and these outcomes can result in an array of morbidities in both mother and baby, and in the most severe cases in mortality. We need to know more about normal pregnancy and where the important triggers are for failure. This prompted us to collect a large set of biological samples with matching clinical data from over 2500 normal and abnormal pregnancies, for use in research into these conditions. This paper outlines the nature of these sample sets and their availability to academia and industry, with the intention that their widespread use in research will make significant contributions to the improvement of maternal and fetal health worldwide (http://www.ucl.ac.uk/tapb/sample-and-data-collections-at-ucl/biobanks-ucl/baby-biobank).
AU  - Leon,LJ
AU  - Solanky,N
AU  - Stalman,SE
AU  - Demetriou,C
AU  - Abu-Amero,S
AU  - Stanier,P
AU  - Regan,L
AU  - Moore,GE
DO  - 10.1016/j.placenta.2016.08.085
EP  - 37
PY  - 2016///
SN  - 1532-3102
SP  - 31
TI  - A new biological and clinical resource for research into pregnancy complications: The Baby Bio Bank
T2  - Placenta
UR  - http://dx.doi.org/10.1016/j.placenta.2016.08.085
UR  - http://www.ncbi.nlm.nih.gov/pubmed/27697219
UR  - http://hdl.handle.net/10044/1/41504
VL  - 46
ER  -
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