Imperial College London
Dr Lesley Rushton

DrLesleyRushton

Faculty of Medicine, School of Public Health

Emeritus Reader of Occupational Epidemiology
 
 
 
//

Contact

 

l.rushton

 
 
//

Location

 

Medical SchoolSt Mary's Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Fortunato:2015:10.1038/bjc.2014.599,
author = {Fortunato, L and Rushton, L},
doi = {10.1038/bjc.2014.599},
journal = {British Journal of Cancer},
pages = {1805--1815},
title = {Stomach cancer and occupational exposure to asbestos: a meta-analysis of occupational cohort studies},
url = {http://dx.doi.org/10.1038/bjc.2014.599},
volume = {112},
year = {2015}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - background:  A recent Monographs Working Group of the International Agency for Research on Cancer concluded that there is limited evidence for a causal association between exposure to asbestos and stomach cancer.methods:  We performed a meta-analysis to quantitatively evaluate this association. Random effects models were used to summarise the relative risks across studies. Sources of heterogeneity were explored through subgroup analyses and meta-regression.results:  We identified 40 mortality cohort studies from 37 separate papers, and cancer incidence data were extracted for 15 separate cohorts from 14 papers. The overall meta-SMR for stomach cancer for total cohort was 1.15 (95% confidence interval 1.03–1.27), with heterogeneous results across studies. Statistically significant excesses were observed in North America and Australia but not in Europe, and for generic asbestos workers and insulators. Meta-SMRs were larger for cohorts reporting a SMR for lung cancer above 2 and cohort sizes below 1000.conclusions:  Our results support the conclusion by IARC that exposure to asbestos is associated with a moderate increased risk of stomach cancer.
AU  - Fortunato,L
AU  - Rushton,L
DO  - 10.1038/bjc.2014.599
EP  - 1815
PY  - 2015///
SN  - 1532-1827
SP  - 1805
TI  - Stomach cancer and occupational exposure to asbestos: a meta-analysis of occupational cohort studies
T2  - British Journal of Cancer
UR  - http://dx.doi.org/10.1038/bjc.2014.599
UR  - http://hdl.handle.net/10044/1/37437
VL  - 112
ER  -
Download