Laura is a Research Fellow in the Department of Mechanical Engineering at Imperial College London. Her research activity focuses on biological flows, in particular flow and aerosol deposition in the respiratory airways and the development of numerical algorithms for high-fidelity, large-scale computations of complex physiological flows. Her work on pulmonary drug delivery relies on in silico models to develop new understanding of the deposition of inhaled particles and to optimise drug delivery to the lungs.
For further details, please visit the group website.
Imperial College London
- PhD in Computational Fluid Dynamics, A robust immersed boundary method for flow in complex geometries: Study of aerosol deposition in the human extrathoracic airways, 2012
- MEng in Mechanical Engineering, 2007
Nicolaou L, 2018, Inertial and gravitational effects on aerosol deposition in the conducting airways, Journal of Aerosol Science, Vol:120, ISSN:0021-8502, Pages:32-51
Koullapis P, Nicolaou L, Kassinos SC, 2018, In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways, Journal of Aerosol Science, Vol:117, ISSN:0021-8502, Pages:164-188
et al., 2017, Regional aerosol deposition in the human airways: the SimInhale benchmark case and a critical assessment of in silico methods, European Journal of Pharmaceutical Sciences, Vol:113, ISSN:0928-0987, Pages:77-94
Nicolaou L, Zaki TA, 2016, Characterization of aerosol Stokes number in 90◦ bends and idealized extrathoracic airways, Journal of Aerosol Science, Vol:102, ISSN:0021-8502, Pages:105-127
Nicolaou L, Jung SY, Zaki TA, 2015, A robust direct-forcing immersed boundary method with enhanced stability for moving body problems in curvilinear coordinates, Computers & Fluids, Vol:119, ISSN:0045-7930, Pages:101-114
Nicolaou L, Zaki TA, 2012, Direct numerical simulations of flow in realistic mouth–throat geometries, Journal of Aerosol Science, Vol:57, ISSN:1879-1964, Pages:71-87