We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.
I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.
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Henderson LD, Beeby M, 2018, High-Throughput Electron Cryo-tomography of Protein Complexes and Their Assembly., Methods Mol Biol, Vol:1764, Pages:29-44
Chaban B, Coleman I, Beeby M, 2018, Evolution of higher torque in Campylobacter-type bacterial flagellar motors, Scientific Reports, Vol:8, ISSN:2045-2322
et al., 2017, Short FtsZ filaments can drive asymmetric cell envelope constriction at the onset of bacterial cytokinesis, Embo Journal, Vol:36, ISSN:0261-4189, Pages:1577-1589
et al., 2017, Nanoscale-length control of the flagellar driveshaft requires hitting the tethered outer membrane, Science, Vol:356, ISSN:0036-8075, Pages:197-200
et al., 2017, Expanding the archaellum regulatory network - the eukaryotic protein kinases ArnC and ArnD influence motility of Sulfolobus acidocaldarius, Microbiologyopen, Vol:6, ISSN:2045-8827