We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.
I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.
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et al., 2019, γ-proteobacteria eject their polar flagella under nutrient depletion, retaining flagellar motor relic structures, Plos Biology, Vol:17, ISSN:1544-9173
et al., 2019, Simulations suggest a constrictive force is required for Gram-negative bacterial cell division, Nature Communications, Vol:10, ISSN:2041-1723