We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.
For full details, please visit our lab website
I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.
Beeby lab, June 2016. L-R: Josie, Hazel, Teige, Bonnie, Charles, Amanda, Morgan, Louie, Siying
et al., 2017, ArnS, a kinase involved in starvation-induced archaellum expression., Mol Microbiol, Vol:103, Pages:181-194
et al., 2017, Expanding the archaellum regulatory network - the eukaryotic protein kinases ArnC and ArnD influence motility of Sulfolobus acidocaldarius., Microbiologyopen, Vol:6
et al., 2016, Diverse high-torque bacterial flagellar motors assemble wider stator rings using a conserved protein scaffold, Proceedings of the National Academy of Sciences of the United States of America, Vol:113, ISSN:0027-8424, Pages:E1917-E1926
Taylor WR, Matthews-Palmer TRS, Beeby M, 2016, Molecular Models for the Core Components of the Flagellar Type-III Secretion Complex, Plos One, Vol:11, ISSN:1932-6203
et al., 2016, Coarse-Grained Simulations Reveal Mechanisms of Bacterial Morphogenesis, 60th Annual Meeting of the Biophysical-Society, CELL PRESS, Pages:468A-468A, ISSN:0006-3495