We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.
I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.
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Beeby M, 2019, Evolution of a family of molecular Rube Goldberg contraptions, Plos Biology, Vol:17, ISSN:1544-9173
et al., γ-proteobacteria eject their polar flagella under nutrient depletion, retaining flagellar motor relic structures, Plos Biology, ISSN:1544-9173
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et al., 2018, Giant flagellins form thick flagellar filaments in two species of marine gamma-proteobacteria, Plos One, Vol:13, ISSN:1932-6203
et al., 2018, Bacterial Flagellins: Does Size Matter?, Trends in Microbiology, Vol:26, ISSN:0966-842X, Pages:575-581