Imperial College London

DrMorganBeeby

Faculty of Natural SciencesDepartment of Life Sciences

Reader in Structural Biology
 
 
 
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Contact

 

m.beeby Website

 
 
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Location

 

502Sir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Cohen:2019:10.1101/616649,
author = {Cohen, EJ and Quek, RT and Beeby, M},
doi = {10.1101/616649},
title = {A<i>tetRA</i>-based promoter system for the generation of conditional knockouts in<i>Campylobacter jejuni</i>},
url = {http://dx.doi.org/10.1101/616649},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - <jats:title>Abstract</jats:title><jats:p><jats:italic>Campylobacter jejuni</jats:italic>is responsible for tens of millions of cases of gastroenteritis each year. Despite its prevalence and impact on human health, the repertoire of genetic tools available for researchers to study<jats:italic>C. jejuni</jats:italic>remains limited. In order to expand upon the genetic toolkit in this species, we have engineered a system for generating conditional knockouts based on the<jats:italic>tetRA</jats:italic>tetracycline-resistance cassette. This system exhibits tight repressibility and titratability of target-gene expression and will be useful for future research on this important human pathogen.</jats:p>
AU - Cohen,EJ
AU - Quek,RT
AU - Beeby,M
DO - 10.1101/616649
PY - 2019///
TI - A<i>tetRA</i>-based promoter system for the generation of conditional knockouts in<i>Campylobacter jejuni</i>
UR - http://dx.doi.org/10.1101/616649
ER -