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@article{Ortega:2022:10.3389/fmicb.2021.803720,
author = {Ortega, D and Beeby, M},
doi = {10.3389/fmicb.2021.803720},
journal = {Frontiers in Microbiology},
pages = {1--6},
title = {How did the archaellum get its rotation?},
url = {http://dx.doi.org/10.3389/fmicb.2021.803720},
volume = {12},
year = {2022}
}

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TY  - JOUR
AB  - How changes in function evolve fascinates many evolutionary biologists. Particularly captivating is the evolution of rotation in molecular machines, as it evokes familiar machines that we have made ourselves. The archaellum, an archaeal analog of the bacterial flagellum, is one of the simplest rotary motors. It features a long helical propeller attached to a cell envelope-embedded rotary motor. Satisfyingly, the archaellum is one of many members of the large type IV filament superfamily, which includes pili, secretion systems, and adhesins, relationships that promise clues as to how the rotating archaellum evolved from a non-rotary ancestor. Nevertheless,determining exactly how the archaellum got its rotation remains frustratingly elusive. Here we review what is known about how the archaellum got its rotation, what clues exist, and what more is needed to address this question.
AU  - Ortega,D
AU  - Beeby,M
DO  - 10.3389/fmicb.2021.803720
EP  - 6
PY  - 2022///
SN  - 1664-302X
SP  - 1
TI  - How did the archaellum get its rotation?
T2  - Frontiers in Microbiology
UR  - http://dx.doi.org/10.3389/fmicb.2021.803720
UR  - https://www.frontiersin.org/articles/10.3389/fmicb.2021.803720/full
UR  - http://hdl.handle.net/10044/1/93639
VL  - 12
ER  -

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