Imperial College London

DrMorganBeeby

Faculty of Natural SciencesDepartment of Life Sciences

Reader in Structural Biology
 
 
 
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Contact

 

m.beeby Website

 
 
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Location

 

502Sir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Genetics with Statistics - LIFE95010

Aims

By the end of the Genetics section of the module students should be able to (1) Describe factors affecting the expression of genes in eukaryotes, including the phenomenon of epigenetics; (2) Discuss the origin of new genes, evolution of genes and factors affecting population gene frequencies in time and space; (3) Describe the inheritance of complex or quantitative traits, and the use of quantitative trait loci (QTL) in mapping; (4) Discuss how genetic techniques can be applied to natural history, reconstructing relationships (phylogenies) and conservation; (5) Students will demonstrate their competence in genetics techniques by inducing and scoring mutations in Salmonella and conducting a population genetics analysis of microsatellite dataset using standard software such as GENEPOP. By the end of the Statistics section students should be able to (6) Obtain descriptive statistics of the data; (7) Produce meaningful visualizations the data by plotting them for exploration as well as model fitting; (8) Test for certain properties of data, such as normality, log-normality, etc. (9) For two samples, be able choose the appropriate test (e.g., t-test, paired t-test, Mann-Whitney u-test; randomization test etc); (10) Understand and use linear models including linear regression and ANOVA, check model assumptions using QQ plots, residual plots etc; (11) For data with non-normal errors or count data, be able to choose and perform appropriate tests especially generalised linear models (GLMs), and interpret the output

Role

Lecturer

Advanced Bacterial and Eukaryotic Cell Biology - LIFE96002

Aims

This Advanced Cell Biology course studies the cell as the product of the emergent properties of its molecular constituents with focus on the cell as the fundamental unit of life.                                             

Role

Course Leader

Fundamentals of Molecular Biochemistry - LIFE95008

Aims

The aim is to provide an understanding by second year undergraduates of the relationship between macromolecular structure and function in sufficient detail to place this knowledge in the context of earlier courses in biochemistry and to provide the foundation for the treatment of more advanced topics in the final year. In particular the course will give the students insight into the theory and practice of how protein samples can be expressed, purified and engineered for structural and functional analysis. This will include insight into how bioinformatics can inform sample preparation and experimental design, how detailed structural information is obtained and how this can be used to facilitate investigation of function at the molecular level.

Role

Lecturer