Imperial College London

DrMatthewChild

Faculty of Natural SciencesDepartment of Life Sciences

Research Fellow (Sir Henry Dale Fellow)
 
 
 
//

Contact

 

+44 (0)20 7594 5402m.child Website

 
 
//

Location

 

612Sir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Summary

Child lab Research Interests

Our lab uses modern chemical biology techniques to increase our understanding of the basic biology of intracellular pathogens such as Toxoplasma and Plasmodium.

We use drug-like small molecules to ask questions about the interaction of these pathogenic organisms with their chosen host-cell. We do this in the belief that by increasing our understanding we will be better equipped to target and therapeutically treat infections that impact human health.

For more information visit www.laboratorychild.com/

About Dr. Matthew Child

Matthew studied for a PhD in molecular parasitology with Prof. Mike Blackman at the National Institute for Medical Research, London, UK. Afterhis  PhD, he moved to the USA to continue his academic career as a post-doc in the chemical biology-focused laboratory of Prof. Matt Bogyo at Stanford University, California.

Following his return to the UK, Matthew was awarded a Wellcome Trust and Royal Society Sir Henry Dale Fellowship, allowing him to initiate his independent research career and lab at Imperial College London.

Publications

Journals

Child MA, Garland M, Foe I, et al., 2017, Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1, Mbio, Vol:8, ISSN:2150-7511

Bender KO, Garland M, Ferreyra JA, et al., 2015, A small-molecule antivirulence agent for treating Clostridium difficile infection, Science Translational Medicine, Vol:7, ISSN:1946-6234

van der Linden WA, Segal E, Child MA, et al., 2015, Design and Synthesis of Activity-Based Probes and Inhibitors for Bleomycin Hydrolase, Chemistry & Biology, Vol:22, ISSN:1074-5521, Pages:995-1001

Foe IT, Child MA, Majmudar JD, et al., 2015, Global Analysis of Palmitoylated Proteins in Toxoplasma gondii, Cell Host & Microbe, Vol:18, ISSN:1931-3128, Pages:501-511

Treeck M, Sanders JL, Gaji RY, et al., 2014, The Calcium-Dependent Protein Kinase 3 of Toxoplasma Influences Basal Calcium Levels and Functions beyond Egress as Revealed by Quantitative Phosphoproteome Analysis, Plos Pathogens, Vol:10, ISSN:1553-7366

More Publications