Imperial College London
Portrait Picture

Professor M Francesca Cordeiro

Faculty of Medicine, Department of Surgery & Cancer

Chair in Ophthalmology (Clinical)
 
 
 
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Contact

 

m.cordeiro

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Yang:2018:10.3389/fneur.2018.00338,
author = {Yang, E and Al-Mugheiry, TS and Normando, EM and Cordeiro, MF},
doi = {10.3389/fneur.2018.00338},
journal = {Frontiers in Neurology},
title = {Real-time imaging of retinal cell apoptosis by confocal scanning laser ophthalmoscopy and its role in glaucoma},
url = {http://dx.doi.org/10.3389/fneur.2018.00338},
volume = {9},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Glaucoma is one of the leading causes of irreversible blindness in the world. It is characterized by the progressive loss of retinal ganglion cells (RGCs), mainly through the process of apoptosis. Glaucoma patients often come to clinical attention when irreversible loss of visual function has been already established; therefore, early recognition of RGC apoptosis is inordinately important in disease prevention. The novel technology called Detection of Apoptosing Retinal Cells (DARC) allows real-time in vivo quantification of apoptosing cells through the use of a fluorescent biomarker and a confocal scanning ophthalmoscope. A recent Phase I clinical trial has evaluated the safety of DARC and its ability to detect retinal apoptosis in glaucoma patients and healthy volunteers. Results suggest that DARC may have potential in the early detection of glaucoma, which could help alleviate the medical, social, and economic burden associated with this blinding condition.
AU  - Yang,E
AU  - Al-Mugheiry,TS
AU  - Normando,EM
AU  - Cordeiro,MF
DO  - 10.3389/fneur.2018.00338
PY  - 2018///
SN  - 1664-2295
TI  - Real-time imaging of retinal cell apoptosis by confocal scanning laser ophthalmoscopy and its role in glaucoma
T2  - Frontiers in Neurology
UR  - http://dx.doi.org/10.3389/fneur.2018.00338
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432399900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/60660
VL  - 9
ER  -
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