Publications
173 results found
Quattrocchi E, Dallman MJ, Feldmann M, 2000, Adenovirus-mediated gene trans fer of CTLA-4Ig fusion protein in the suppression of experimental autoimmune arthritis, ARTHRITIS AND RHEUMATISM, Vol: 43, Pages: 1688-1697, ISSN: 0004-3591
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- Citations: 54
Hoyne GF, Dallman MJ, Lamb JR, 2000, T-cell regulation of peripheral tolerance and immunity: the potential role for Notch signalling, IMMUNOLOGY, Vol: 100, Pages: 281-288, ISSN: 0019-2805
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- Citations: 32
Bugeon L, Syed N, Dallman MJ, 2000, A fast and efficient method for transiently transfecting ES cells: application to the development of systems for conditional gene expression, TRANSGENIC RESEARCH, Vol: 9, Pages: 229-232, ISSN: 0962-8819
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- Citations: 10
Deonarain R, Alcamà A, Alexiou M, et al., 2000, Impaired antiviral response and alpha/beta interferon induction in mice lacking beta interferon, JOURNAL OF VIROLOGY, Vol: 74, Pages: 3404-3409, ISSN: 0022-538X
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- Citations: 137
Hoyne GF, Le Roux I, Corsin-Jimenez M, et al., 2000, <i>Serrate1</i>-induced <i>Notch</i> signalling regulates the decision between immunity and tolerance made by peripheral CD4<SUP>+</SUP> T cells, INTERNATIONAL IMMUNOLOGY, Vol: 12, Pages: 177-185, ISSN: 0953-8178
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- Citations: 169
Hirschberg S, Layton GT, Harris SJ, et al., 1999, CD4<SUP>+</SUP> T cells induced by virus-like particles expressing a major T cell epitope downregulate IL-5 production in an ongoing immune response to Der p 1 independently of IFN-γ production, INTERNATIONAL IMMUNOLOGY, Vol: 11, Pages: 1927-1933, ISSN: 0953-8178
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- Citations: 8
Hirschberg S, Layton GT, Harris SJ, et al., 1999, CD4(+) T cells induced by virus-like particles expressing a major T cell epitope down-regulate IL-5 production in an ongoing immune response to Der p 1 independently of IFN-gamma production., Int Immunol, Vol: 11, Pages: 1927-1934, ISSN: 0953-8178
It has been previously demonstrated that hybrid Ty virus-like particles (VLP) prime effective CD8(+) and CD4(+) T cell responses. In this study, we investigated the effect of treating mice with Ty VLP carrying the immunodominant epitope of Der p 1 after sensitizing them to the group 1 allergen of the house dust mite Dermatophagoides pteronyssinus (Der p 1), under conditions that induce T(h)2 immunity. We show that i.p. treatment with the hybrid VLP abrogated allergen-specific IL-5 production and reduced allergen-specific cell proliferation. This suppression of the response was mediated by CD4(+) T cells and was not accompanied by an increase in IFN-gamma production.
Hoyne GF, Dallman MJ, Lamb JR, 1999, Linked suppression in peripheral T cell tolerance to the house bust mite derived allergen Der p 1, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, Vol: 118, Pages: 122-124, ISSN: 1018-2438
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- Citations: 27
Croxford JL, O'Neill JK, Ali RR, et al., 1998, Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 28, Pages: 3904-3916, ISSN: 0014-2980
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- Citations: 42
Young NT, Rust NA, Dallman MJ, et al., 1998, Independent contributions of HLA epitopes and killer inhibitory receptor expression to the functional alloreactive specificity of natural killer cells, HUMAN IMMUNOLOGY, Vol: 59, Pages: 700-712, ISSN: 0198-8859
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- Citations: 13
Dallman MJ, 1998, Polymerase chain reaction methods in immunology, TRANSPLANTATION PROCEEDINGS, Vol: 30, Pages: 2367-2369, ISSN: 0041-1345
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- Citations: 2
Young NT, Roelen DL, Dallman MJ, et al., 1998, HLA-DRB1 amino acid disparity is the major stimulus of interleukin-2 production by alloreactive helper T-lymphocytes, IMMUNOGENETICS, Vol: 47, Pages: 310-317, ISSN: 0093-7711
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- Citations: 8
Porter ACG, Dallman MJ, 1997, Gene targeting - Techniques and applications to transplantation, TRANSPLANTATION, Vol: 64, Pages: 1227-1235, ISSN: 0041-1337
Ozasa T, Newton MR, Dallman MJ, et al., 1997, Cytokine gene expression in pancreatic islet grafts in the rat, TRANSPLANTATION, Vol: 64, Pages: 1152-1159, ISSN: 0041-1337
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- Citations: 29
Montgomery RA, Dallman MJ, 1997, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny, CYTOKINE, Vol: 9, Pages: 717-726, ISSN: 1043-4666
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- Citations: 18
Oral HB, Larkin DFP, Fehervari Z, et al., 1997, Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea, GENE THERAPY, Vol: 4, Pages: 639-647, ISSN: 0969-7128
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- Citations: 79
Toogood GJ, Rankin AM, Tam PKH, et al., 1997, The immune response following small bowel transplantation .2. A very early cytokine response in the gut-associated lymphoid tissue, TRANSPLANTATION, Vol: 63, Pages: 1118-1123, ISSN: 0041-1337
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- Citations: 13
Young NT, Roelen DL, Iggo N, et al., 1997, Effect of one-HLA-haplotype-matched and HLA-mismatched blood transfusions on recipient T lymphocyte allorepertoires, TRANSPLANTATION, Vol: 63, Pages: 1160-1165, ISSN: 0041-1337
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- Citations: 15
Willetts IE, Tam PKH, Morris PJ, et al., 1997, Treatment with an HLA-peptide and cyclosporine A prolongs rat small bowel allograft survival, JOURNAL OF PEDIATRIC SURGERY, Vol: 32, Pages: 469-472, ISSN: 0022-3468
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- Citations: 6
McLean AG, Hughes D, Welsh KI, et al., 1997, Patterns of graft infiltration and cytokine gene expression during the first 10 days of kidney transplantation, TRANSPLANTATION, Vol: 63, Pages: 374-380, ISSN: 0041-1337
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- Citations: 57
Young NT, Roelen DL, Bunce M, et al., 1997, Alloreactive helper T-lymphocyte precursor frequencies correlate with HLA-DRB1 antigen amino acid residue mismatches, 12th International Histocompatibility Conference - HLA, Publisher: EDITIONS EDK, Pages: 501-503
Dallman MJ, 1996, Molecular biology of the allograft response, TRANSPLANTATION PROCEEDINGS, Vol: 28, Pages: 2-6, ISSN: 0041-1345
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- Citations: 6
Toogood GJ, Rankin AM, Tam PKH, et al., 1996, The immune response following small bowel transplantation .1. An unusual pattern of cytokine expression, TRANSPLANTATION, Vol: 62, Pages: 851-855, ISSN: 0041-1337
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- Citations: 20
Young NT, Roelen DL, Wood KJ, et al., 1996, Primary alloreactive cytotoxic T-lymphocytes are not commonly restricted by self-HLA Class I antigens, HUMAN IMMUNOLOGY, Vol: 50, Pages: 38-46, ISSN: 0198-8859
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- Citations: 5
Young NT, Roelen DL, Dallman MJ, et al., 1996, Enumeration of human alloreactive helper T lymphocyte precursor frequencies by limiting dilution analysis of interleukin-2 production, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 195, Pages: 33-41, ISSN: 0022-1759
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- Citations: 10
Young NT, Roelen DL, Bunce M, et al., 1996, Alloreactive helper T-lymphocyte precursor frequencies correlate with HLA-DR antigen amino acid residue mismatches, HUMAN IMMUNOLOGY, Vol: 47, Pages: O877-O877, ISSN: 0198-8859
Ball ST, Dallman MJ, 1995, Transplantation immunology., Curr Opin Nephrol Hypertens, Vol: 4, Pages: 465-471, ISSN: 1062-4821
The success of transplantation is such that it is now the treatment of choice for many of those requiring renal replacement therapy. The use of other solid organs, including liver, pancreas, heart and lung, continues to progress. This article reviews some recent advances in our understanding of the immunological response to alloantigen and xenoantigen.
DALLMAN MJ, 1995, CYTOKINES AND TRANSPLANTATION - TH1/TH2 REGULATION OF THE IMMUNE-RESPONSE TO SOLID-ORGAN TRANSPLANTS IN THE ADULT, CURRENT OPINION IN IMMUNOLOGY, Vol: 7, Pages: 632-638, ISSN: 0952-7915
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- Citations: 131
TACKE M, CLARK GJ, DALLMAN MJ, et al., 1995, CELLULAR-DISTRIBUTION AND COSTIMULATORY FUNCTION OF RAT CD28 - REGULATED EXPRESSION DURING THYMOCYTE MATURATION AND INDUCTION OF CYCLOSPORINE-A SENSITIVITY OF COSTIMULATED T-CELL RESPONSES BY PHORBOL ESTER, JOURNAL OF IMMUNOLOGY, Vol: 154, Pages: 5121-5127, ISSN: 0022-1767
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- Citations: 46
HIGGINS RM, DALLMAN MJ, 1995, ENHANCEMENT AND INHIBITION OF CELLULAR RESPONSIVENESS MEDIATED BY THE ANTILEUKOCYTE MONOCLONAL-ANTIBODY NDS-71, IMMUNOLOGY LETTERS, Vol: 46, Pages: 37-42, ISSN: 0165-2478
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