Imperial College London

Dr. Maria de Gracia Dominguez-Barrera, PhD

Faculty of MedicineFaculty of Medicine Centre

Honorary Clinical Senior Lecturer



+44 (0)20 3312 1145m.dominquez-barrera




Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus





Mari has been Honorary Clinical Lecturer in Child and Adolescent Psychiatry at Imperial College London since October 2012. She works for the NHS as a locum Consultant Child & Adolescent Psychiatrist at Hillingdon CAMHS and Harrow & Hillingdon Early Intervention Service for Psychosis (Central and North West London NHS Foundation Trust).


Mari’s graduated in medicine at the University of Navarra (Pamplona, Spain). Her interest in academic psychiatry developed when she was a clinical psychiatry trainee. She completed her specialist clinical training in psychiatry at the Hospital Santiago Apostol in Vitoria (Spain), whilst she began her academic career in the Department of Neuroscience, University of the Basque Country (Bilbao-Leioa, Spain). In 2006, she obtained a Marie Curie Early Stage Research Training Fellowship, and moved to the Department of Psychiatry and Neuropsychology, Maastricht University (Maastricht, The Netherlands), where she developed her interest and expertise in psychiatric epidemiology & meta-analytic studies in the field of psychosis research. After obtaining her PhD entitled 'A Dynamic Model of the Onset of Clinical Psychosis from an Epidemiological Perspective' in 2009, Mari continued to work as a postdoctoral researcher at Maastricht University for one year. In 2010, Mari obtained an Alicia Koplowitz fellowship and moved to the Academic Unit of Child and Adolescent Psychiatry at Imperial College London (London, UK) where she continues her teaching and research work as a honorary Clinical Lecturer.

Mari’s research examines the psychosis phenotype and investigates the dynamic process driving psychosis expression from mental wellness to onset of clinical psychosis. From examining the dimensional structure of psychosis in the general population, her work has expanded to investigate the developmental expression of psychosis in clinical samples of adolescents, as an age period associated with increased risk for the emergence of psychosis, examining treatment delay and pathways to care during adolescence. The significance of her research work has been reflected in first author publications in international peer-reviewed journals and oral presentations at international conferences in psychiatry (SIRS-2008, AEP-2008, ICOSR-2009, SIRS-2010, IEPA-2010, EPA-2014) and child and adolescent psychiatry (RCPsych-2001, AEPNYA-2011, IACAPAP-2012, ESCAP-2013, ESCAP-2015). In 2014, Mari was awarded the 2014 European Psychiatry Association research prize for the best scientific paper in child and adolescent psychiatry for the work on 'Duration of untreated psychosis in adolescents: ethnic differences and clinical profiles'. Since 2014, Mari is the president of the Association of Scientists in Child and Adolescent Mental Health - Alicia Koplowitz Foundation. 



Dominguez M-D-G, Fisher HL, Major B, et al., 2013, Duration of untreated psychosis in adolescents: Ethnic differences and clinical profiles, Schizophrenia Research, Vol:150, ISSN:0920-9964, Pages:526-532

Smeets F, Lataster T, Dominguez M-D-G, et al., 2012, Evidence that onset of psychosis in the population reflects early hallucinatory experiences that through environmental risks and affective dysregulation become complicated by delusions., Schizophr Bull, Vol:38, Pages:531-542

Schutters SIJ, Dominguez M-D-G, Knappe S, et al., 2012, The association between social phobia, social anxiety cognitions and paranoid symptoms., Acta Psychiatr Scand, Vol:125, Pages:213-227

van Rossum I, Dominguez M-D-G, Lieb R, et al., 2011, Affective dysregulation and reality distortion: a 10-year prospective study of their association and clinical relevance., Schizophr Bull, Vol:37, Pages:561-571

van der Werf M, Thewissen V, Dominguez MD, et al., 2011, Adolescent development of psychosis as an outcome of hearing impairment: a 10-year longitudinal study., Psychol Med, Vol:41, Pages:477-485

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