I am a Professor of Practice and Consultant Histopathologist at the Department of Histopathology, Imperial College London, Hammersmith Campus. My main area of practice and interest is Gynaecologic pathology, and in particular Gynaecological tumour pathology.
My job at Imperial College is a reflection of the ethos of the Academic Health Sciences Centre, where service work, teaching and research work are complimentary.
My research focuses on the identification of diagnostic and prognostic biomarkers and potential therapeutic targets for epithelial tumours, particularly gynaecological tumours. I have special interest in borderline ovarian tumours and sex cord stromal tumours. Recently published work from our laboratory shows that there are molecular subtypes of serous borderline ovarian tumours. Continued work in this area will hopefully lead to the identification of predictive biomarkers for the biological behaviour of individual borderline tumours, as well as the identification of potential therapeutic targets for tumours showing aggressive behaviour; both of which remain to be unmet clinical needs.
et al., 2019, A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases, Modern Pathology, Vol:32, ISSN:0893-3952, Pages:1834-1846
et al., 2019, Toxic shock syndrome toxin-1 evaluation and antibiotic impact in a transgenic model of staphylococcal soft tissue infection, Msphere, Vol:4, ISSN:2379-5042
et al., 2020, The SHOC2 phosphatase complex as a therapeutic target for ERK-pathway inhibition in RAS-driven tumors., AACR Special Conference on Targeting RAS-Driven Cancers, AMER ASSOC CANCER RESEARCH, Pages:65-66, ISSN:1541-7786
et al., 2020, Unusual Adnexal Tumors with Recurring STK11 Mutations: A Clinicopathological Study of 11 Cases Including 4 in Patients with Peutz-Jeghers Syndrome, 109th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), NATURE PUBLISHING GROUP, Pages:1016-1017, ISSN:0893-3952
et al., 2020, Unusual Adnexal Tumors with Recurring STK11 Mutations: A Clinicopathological Study of 11 Cases Including 4 in Patients with Peutz-Jeghers Syndrome, 109th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), NATURE PUBLISHING GROUP, Pages:1016-1017, ISSN:0023-6837