Imperial College London

Professor Matthew J. Fuchter

Faculty of Natural SciencesDepartment of Chemistry

Professor of Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 5815m.fuchter

 
 
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Location

 

401CMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Scott:2016:10.1002/anie.201606639,
author = {Scott, DJ and Phillips, NA and Sapsford, JS and Deacy, AC and Fuchter, MJ and Ashley, AE},
doi = {10.1002/anie.201606639},
journal = {Angewandte Chemie International Edition},
pages = {14738--14742},
title = {Versatile Catalytic Hydrogenation Using A Simple SnIV Lewis Acid},
url = {http://dx.doi.org/10.1002/anie.201606639},
volume = {55},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Despite the rapid development of frustrated Lewis pair (FLP) chemistry over the last ten years, its application in catalytic hydrogenations remains dependent on a narrow family of structurally similar early main-group Lewis acids (LAs), inevitably placing limitations on reactivity, sensitivity and substrate scope. Herein we describe the FLP-mediated H2 activation and catalytic hydrogenation activity of the alternative LA iPr3SnOTf, which acts as a surrogate for the trialkylstannylium ion iPr3Sn+, and is rapidly and easily prepared from simple, inexpensive starting materials. This highly thermally robust LA is found to be competent in the hydrogenation of a number of different unsaturated functional groups (which is unique to date for main-group FLP LAs not based on boron), and also displays a remarkable tolerance to moisture.
AU - Scott,DJ
AU - Phillips,NA
AU - Sapsford,JS
AU - Deacy,AC
AU - Fuchter,MJ
AU - Ashley,AE
DO - 10.1002/anie.201606639
EP - 14742
PY - 2016///
SN - 1433-7851
SP - 14738
TI - Versatile Catalytic Hydrogenation Using A Simple SnIV Lewis Acid
T2 - Angewandte Chemie International Edition
UR - http://dx.doi.org/10.1002/anie.201606639
UR - http://hdl.handle.net/10044/1/41125
VL - 55
ER -