Publications
420 results found
Bedard E, McCarthy KP, Dimopoulos K, et al., 2009, Structural Abnormalities of the Pulmonary Trunk in Tetralogy of Fallot and Potential Clinical Implications A Morphological Study, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 54, Pages: 1883-1890, ISSN: 0735-1097
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- Citations: 37
Dimopoulos K, Giannakoulas G, Yuksel S, et al., 2009, Atrial Tachyarrhythmias Late After Fontan Operation Are Related to Increase in Mortality and Hospitalization, 82nd Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S562-S562, ISSN: 0009-7322
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- Citations: 1
Diller G-P, Giardini A, Dimopoulos K, et al., 2009, Predictors of Morbidity and Mortality in Contemporary Fontan Patients: Results From a Multicenter Study Including Cardiopulmonary Exercise Testing in 321 Patients, 82nd Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S561-S562, ISSN: 0009-7322
Dimopoulos K, Inuzuka R, Goletto S, et al., 2009, Improved Survival Amongst Patients With Eisenmenger Syndrome Receiving Advanced Therapy for Pulmonary Arterial Hypertension, 82nd Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S556-S556, ISSN: 0009-7322
Dimopoulos K, Giannakoulas G, Bolger AP, et al., 2009, Natriuretic Peptide Levels Predict Mortality in Adults With Congenital Heart Disease, 82nd Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S601-S601, ISSN: 0009-7322
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- Citations: 1
Corte TJ, Wort SJ, Gatzoulis MA, et al., 2009, Pulmonary vascular resistance predicts early mortality in patients with diffuse fibrotic lung disease and suspected pulmonary hypertension, THORAX, Vol: 64, Pages: 883-888, ISSN: 0040-6376
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- Citations: 86
Tay E, Peset ANA, Papaphylactou M, et al., 2009, Replacement therapy for iron deficiency improves symptoms and exercise capacity in patients with cyanotic heart disease and/or Eisenmenger syndrome, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 901-901, ISSN: 0195-668X
Tay ELW, Frogoudaki A, Inuzuka R, et al., 2009, Exercise intolerance in patients with congenitally corrected transposition of the great arteries relates to right ventricular filling pressures, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 809-809, ISSN: 0195-668X
Alfano D, Li W, Sarubbi B, et al., 2009, Right and left ventricular function and its relationship to functional capacity in adults with unoperated Ebstein's anomaly, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 804-804, ISSN: 0195-668X
Papaphylactou M, Dimopoulos K, Inuzuka R, et al., 2009, Scoliosis as a surrogate skeletal disease in adults with congenital heart disease, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 799-799, ISSN: 0195-668X
Tay E, Josen M, Gibson DG, et al., 2009, Total isovolumic time relates to exercise capacity in patients with transposition of the great arteries after atrial switch, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 400-400, ISSN: 0195-668X
Dimopoulos K, Diller GP, Giannakoulas G, et al., 2009, Anemia in adults with congenital heart disease relates to adverse outcome, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 800-800, ISSN: 0195-668X
Dimopoulos K, Giannakoulas G, Petraco R, et al., 2009, The cardiothoracic ratio: a simple, strong and reproducible marker of disease severity and outcome in adults with congenital heart disease, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 800-800, ISSN: 0195-668X
Gatzoulis MA, Alonso-Gonzalez R, Beghetti M, 2009, Pulmonary arterial hypertension in paediatric and adult patients with congenital heart disease., Eur Respir Rev, Vol: 18, Pages: 154-161
Pulmonary arterial hypertension (PAH) commonly arises in patients with congenital heart disease (CHD). Greater numbers of patients with PAH associated with CHD (PAH-CHD) are now surviving into adulthood, many with increasingly complex cardiac defects. Patients with cardiac defects which result in left-to-right shunting are at risk of developing PAH, owing to the increased shear stress and circumferential stretch induced by increased pulmonary blood flow, which leads to endothelial dysfunction and progressive vascular remodelling and, thus, increased pulmonary vascular resistance. Although PAH-CHD shares similar lung histology with idiopathic PAH, differences do exist between these aetiologies. Management of PAH-CHD can involve surgical correction of the cardiac defect and/or treatment of the PAH, depending on the underlying cardiac defect and status of disease progression. Transplantation surgery can be curative but is not without limitations. The timing of intervention in patients with PAH-CHD is important, but the optimums are sometimes difficult to define, with limited robust data to inform management decisions. Uncontrolled studies suggest that prostacyclin analogues and phosphodiesterase type-5 inhibitors may have benefits in advanced pulmonary vascular disease. In the only randomised controlled trial dedicated to end-stage PAH-CHD, bosentan significantly reduced pulmonary vascular resistance and significantly increased 6-minute walk distance without compromising peripheral oxygen saturation, in patients with Eisenmenger syndrome. These data suggest that targeted therapies are beneficial in the PAH-CHD population, and warrant further research.
Davos CH, Moutafi AC, Alexandridi A, et al., 2009, Heart rate turbulence in adults with repaired tetralogy of Fallot, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 135, Pages: 308-314, ISSN: 0167-5273
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- Citations: 6
Giannakoulas G, Dimopoulos K, Engel R, et al., 2009, Burden of Coronary Artery Disease in Adults With Congenital Heart Disease and Its Relation to Congenital and Traditional Heart Risk Factors, AMERICAN JOURNAL OF CARDIOLOGY, Vol: 103, Pages: 1445-1450, ISSN: 0002-9149
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- Citations: 116
Diller G-P, Okonko DO, Uebing A, et al., 2009, Impaired heart rate response to exercise in adult patients with a systemic right ventricle or univentricular circulation: Prevalence, relation to exercise, and potential therapeutic implications, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 134, Pages: 59-66, ISSN: 0167-5273
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- Citations: 27
Lam Y-Y, Mullen MJ, Kaya MG, et al., 2009, Left ventricular long axis dysfunction in adults with "corrected'' aortic coarctation is related to an older age at intervention and increased aortic stiffness, HEART, Vol: 95, Pages: 733-739, ISSN: 1355-6037
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- Citations: 35
Feinstein JA, Gatzoulis MA, 2009, Use of magnetic resonance imaging and computed tomography, CARDIOLOGY IN THE YOUNG, Vol: 19, Pages: 16-22, ISSN: 1047-9511
Giardini A, Hager A, Lammers AE, et al., 2009, Ventilatory Efficiency and Aerobic Capacity Predict Event-Free Survival in Adults With Atrial Repair for Complete Transposition of the Great Arteries, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 53, Pages: 1548-1555, ISSN: 0735-1097
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- Citations: 93
Gelson E, Gatzoulis MA, Steer P, et al., 2009, Heart disease - why is maternal mortality increasing?, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 116, Pages: 609-611, ISSN: 1470-0328
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- Citations: 29
Griffin HR, Hall DH, Topf A, et al., 2009, Genetic Variation in <i>VEGF</i> Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation, PLOS ONE, Vol: 4, ISSN: 1932-6203
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- Citations: 20
Diller G-P, Bedard E, Wort SJ, et al., 2009, Response to Letter Regarding Article, "Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension", CIRCULATION, Vol: 119, Pages: E231-E231, ISSN: 0009-7322
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- Citations: 1
Bedard E, Dimopoulos K, Gatzoulis MA, 2009, Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension?, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 256-265, ISSN: 0195-668X
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- Citations: 348
Nijjer S, White S, Gatzoulis MA, 2009, Torsades de Pointes in atrioventricular septal defect, International journal of cardiology, Vol: 134, Pages: e51-52, ISSN: 1874-1754
Complete heart block is a known association of atrioventricular septal defect. Bradycardia secondary to heart block can lead to abnormal QT prolongation and precipitate Torsades de Pointes and arrest. Here, a case report of these events is described, together with a brief literature review.
Nicol ED, Kafka H, Stirrup J, et al., 2009, A single, comprehensive non-invasive cardiovascular assessment in pulmonary arterial hypertension: combined computed tomography pulmonary and coronary …, International journal of …
Fung WLA, Chow EWC, Webb GD, et al., 2008, Extracardiac features predicting 22q11.2 Deletion Syndrome in adult congenital heart disease, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 131, Pages: 51-58, ISSN: 0167-5273
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- Citations: 40
Papadopoulou SA, Dimopoulos K, Gatzoulis MA, 2008, Near miss sudden cardiac death on a young patient with repaired atrioventricular septal defect, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 130, Pages: E117-E118, ISSN: 0167-5273
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- Citations: 2
Giannakoulas G, Dimopoulas K, Gatzoulis MA, 2008, Bosentan in mild pulmonary hypertension, LANCET, Vol: 372, Pages: 1730-1731, ISSN: 0140-6736
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- Citations: 4
Dimopoulos K, Giannakoulas G, Wort SJ, et al., 2008, Pulmonary arterial hypertension in adults with congenital heart disease: distinct differences from other causes of pulmonary arterial hypertension and management implications, CURRENT OPINION IN CARDIOLOGY, Vol: 23, Pages: 545-554, ISSN: 0268-4705
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- Citations: 56
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