Imperial College London

Professor Mark Griffiths

Faculty of MedicineNational Heart & Lung Institute

Honorary Principal Research Fellow



+44 (0)20 7351 8523 ext 2030m.griffiths




363Sir Alexander Fleming BuildingSouth Kensington Campus





Professor of Critical Care Medicine  at the National Heart and Lung Institute and Consultant Physician at St Bartholomew's Hospital, London. Having qualified at London University in 1987, he was appointed as a consultant in 2001.

Clinical interests include ARDS, ICU acquired weakness, human models of ARDS and other aspects of critical illness, and extra-corporeal gas exchange techniques. 

His research is focussed on cellular and molecular mechanisms of acute lung injury and repair. Current, focus of research is the effect of mechanical forces on lung injury and repair; current models include cellular stretch, in vivo murine ventilator-induced lung injury (with Prof Takata, SORA ICL), EVLP and surgical models of acute lung injury and multiple organ dysfunction. He is involved in multidisciplinary translational research which integrates basic science with clinical studies, thereby providing novel insights into critical illness.



Ng-Blichfeldt JP, Alçada J, Montero MA, et al., 2017, Deficient retinoid-driven angiogenesis may contribute to failure of adult human lung regeneration in emphysema., Thorax

Poobalasingam T, Yates LL, Walker SA, et al., 2017, Heterozygous Vangl2(Looptail) mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair., Dis Model Mech, Vol:10, Pages:409-423

Bastin AJ, Davies N, Lim E, et al., 2016, Systemic inflammation and oxidative stress post-lung resection: Effect of pretreatment with N-acetylcysteine, Respirology, Vol:21, ISSN:1323-7799, Pages:180-187

Griffiths M, Proudfoot A, 2016, ARDS, up close and personal, Thorax, Vol:71, ISSN:0040-6376, Pages:1073-1075


Thakuria L, Davey R, Romano R, et al., Inflation pressures are associated with outcomes in ventilated patients after lung transplantation, The European Respiratory Society Annual Meeting, Pages:P259-P259, ISSN:1399-3003

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