Imperial College London

DrMichaelKoa-Wing

Faculty of MedicineNational Heart & Lung Institute

Honorary Clinical Senior Lecturer
 
 
 
//

Contact

 

+44 (0)20 3313 1664m.koa-wing05

 
 
//

Location

 

Cardiac Catheter Laboratory (EP)Hammersmith HospitalHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

46 results found

Shun-Shin MJ, Leong KMW, Ng FS, Linton NWF, Whinnett ZI, Koa-Wing M, Qureshi N, Lefroy DC, Harding SE, Lim PB, Peters NS, Francis DP, Varnava AM, Kanagaratnam Pet al., 2019, Ventricular conduction stability test: a method to identify and quantify changes in whole heart activation patterns during physiological stress., Europace

AIMS: Abnormal rate adaptation of the action potential is proarrhythmic but is difficult to measure with current electro-anatomical mapping techniques. We developed a method to rapidly quantify spatial discordance in whole heart activation in response to rate cycle length changes. We test the hypothesis that patients with underlying channelopathies or history of aborted sudden cardiac death (SCD) have a reduced capacity to maintain uniform activation following exercise. METHODS AND RESULTS: Electrocardiographical imaging (ECGI) reconstructs >1200 electrograms (EGMs) over the ventricles from a single beat, providing epicardial whole heart activation maps. Thirty-one individuals [11 SCD survivors; 10 Brugada syndrome (BrS) without SCD; and 10 controls] with structurally normal hearts underwent ECGI vest recordings following exercise treadmill. For each patient, we calculated the relative change in EGM local activation times (LATs) between a baseline and post-exertion phase using custom written software. A ventricular conduction stability (V-CoS) score calculated to indicate the percentage of ventricle that showed no significant change in relative LAT (<10 ms). A lower score reflected greater conduction heterogeneity. Mean variability (standard deviation) of V-CoS score over 10 consecutive beats was small (0.9 ± 0.5%), with good inter-operator reproducibility of V-CoS scores. Sudden cardiac death survivors, compared to BrS and controls, had the lowest V-CoS scores post-exertion (P = 0.011) but were no different at baseline (P = 0.50). CONCLUSION: We present a method to rapidly quantify changes in global activation which provides a measure of conduction heterogeneity and proof of concept by demonstrating SCD survivors have a reduced capacity to maintain uniform activation following exercise.

JOURNAL ARTICLE

Leong KMW, Ng FS, Jones S, Chow J-J, Qureshi N, Koa-Wing M, Linton NWF, Whinnett ZI, Lefroy DC, Davies DW, Lim PB, Peters NS, Kanagaratnam P, Varnava AMet al., 2019, Prevalence of spontaneous type I ECG pattern, syncope, and other risk markers in sudden cardiac arrest survivors with Brugada syndrome, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, Vol: 42, Pages: 257-264, ISSN: 0147-8389

JOURNAL ARTICLE

Arnold AD, Shun-Shin MJ, Keene D, Howard JP, Sohaib SMA, Wright IJ, Cole GD, Qureshi NA, Lefroy DC, Koa-Wing M, Linton NWF, Lim PB, Peters NS, Davies DW, Muthumala A, Tanner M, Ellenbogen KA, Kanagaratnam P, Francis DP, Whinnett ZIet al., 2018, His Resynchronization Versus Biventricular Pacing in Patients With Heart Failure and Left Bundle Branch Block, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 72, Pages: 3112-3122, ISSN: 0735-1097

JOURNAL ARTICLE

, 2018, B-AB01-01 to B-AB42-05, Pages: S1-S107, ISSN: 1547-5271

CONFERENCE PAPER

Luther V, Qureshi N, Lim PB, Koa-Wing M, Jamil-Copley S, Ng FS, Whinnett Z, Davie DW, Peters NS, Kanagaratnam P, Linton Net al., 2018, Isthmus sites identified by Ripple Mapping are usually anatomically stable: A novel method to guide atrial substrate ablation?, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Vol: 29, Pages: 404-411, ISSN: 1045-3873

JOURNAL ARTICLE

Leong KMW, Chow J-J, Ng FS, Falaschetti E, Qureshi N, Koa-Wing M, Linton NWF, Whinnett ZI, Lefroy DC, Davies DW, Lim PB, Peters NS, Kanagaratnam P, Varnava AMet al., 2018, Comparison of the Prognostic Usefulness of the European Society of Cardiology and American Heart Association/American College of Cardiology Foundation Risk Stratification Systems for Patients With Hypertrophic Cardiomyopathy, AMERICAN JOURNAL OF CARDIOLOGY, Vol: 121, Pages: 349-355, ISSN: 0002-9149

JOURNAL ARTICLE

Sau A, Sikkel MB, Luther V, Wright I, Guerrero F, Koa-Wing M, Lefroy D, Linton N, Qureshi N, Whinnett Z, Lim PB, Kanagaratnam P, Peters NS, Davies DWet al., 2017, The sawtooth EKG pattern of typical atrial flutter is not related to slow conduction velocity at the cavotricuspid isthmus, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Vol: 28, Pages: 1445-1453, ISSN: 1045-3873

JOURNAL ARTICLE

Luther V, Sikkel M, Bennett N, Guerrero F, Leong K, Qureshi N, Ng FS, Hayat SA, Sohaib SMA, Malcolme-Lawes L, Lim E, Wright I, Koa-Wing M, Lefroy DC, Linton NWF, Whinnett Z, Kanagaratnam P, Davies W, Peters NS, Lim PBet al., 2017, Visualizing Localized Reentry With Ultra-High Density Mapping in Iatrogenic Atrial Tachycardia Beware Pseudo-Reentry, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 10, ISSN: 1941-3149

JOURNAL ARTICLE

Betts TR, Leo M, Panikker S, Kanagaratnam P, Koa-Wing M, Davies DW, Hildick-Smith D, Wynne DG, Ormerod O, Segal OR, Chow AW, Todd D, Gomez SC, Kirkwood GJ, Fox D, Pepper C, Foran J, Wong Tet al., 2017, Percutaneous Left Atrial Appendage Occlusion Using Different Technologies in the United Kingdom: A Multicenter Registry, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 89, Pages: 484-492, ISSN: 1522-1946

JOURNAL ARTICLE

Leong KMW, Chow J-J, Ng FS, Yates S, Wright I, Luther V, David L, Qureshi N, Koa-Wing M, Whinnett Z, Linton NW, Davies DW, Lim PB, Peters NS, Kanagaratnam P, Varnava Aet al., 2016, RISK STRATIFICATION IN HYPERTROPHIC CARDIOMYOPATHY: EVALUATION OF THE EUROPEAN SOCIETY OF CARDIOLOGY SUDDEN CARDIAC DEATH RISK SCORING SYSTEM, Annual Conference of the British-Cardiovascular-Society (BCS) on Prediction and Prevention, Publisher: BMJ PUBLISHING GROUP, Pages: A104-A105, ISSN: 1355-6037

CONFERENCE PAPER

Luther V, Linton NWF, Jamil-Copley S, Koa-Wing M, Lim PB, Qureshi N, Ng FS, Hayat S, Whinnett Z, Davies DW, Peters NS, Kanagaratnam Pet al., 2016, A Prospective Study of Ripple Mapping the Post-Infarct Ventricular Scar to Guide Substrate Ablation for Ventricular Tachycardia, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 9, ISSN: 1941-3149

JOURNAL ARTICLE

Luther V, Linton NW, Jamil-Copley S, Koa-Wing M, Qureshi N, Ng F, Lim PB, Whinnett Z, Davies DW, Peters NS, Kanagaratnam Pet al., 2016, RIPPLE MAPPING THE VENTRICULAR SCAR: A NOVEL APPROACH TO SUBSTRATE ABLATION OF POST-INFARCT VENTRICULAR TACHYCARDIA TO PREVENT IMPLANTABLE DEFIBRILLATOR THERAPY, Annual Conference of the British-Cardiovascular-Society (BCS) on Prediction and Prevention, Publisher: BMJ PUBLISHING GROUP, Pages: A49-A50, ISSN: 1355-6037

CONFERENCE PAPER

Luther V, Linton NWF, Koa-Wing M, Lim PB, Jamil-Copley S, Qureshi N, Ng FS, Hayat S, Whinnett Z, Davies DW, Peters NS, Kanagaratnam Pet al., 2016, A Prospective Study of Ripple Mapping in Atrial Tachycardias A Novel Approach to Interpreting Activation in Low-Voltage Areas, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 9, ISSN: 1941-3149

JOURNAL ARTICLE

Koa-Wing M, Nakagawa H, Luther V, Jamil-Copley S, Linton N, Sandler B, Qureshi N, Peters NS, Davies DW, Francis DP, Jackman W, Kanagaratnam Pet al., 2015, A diagnostic algorithm to optimize data collection and interpretation of Ripple Maps in atrial tachycardias, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 199, Pages: 391-400, ISSN: 0167-5273

JOURNAL ARTICLE

Koa-Wing M, Jamil-Copley S, Ariff B, Kojodjojo P, Lim PB, Whinnett Z, Rajakulendran S, Malhotra P, Lefroy D, Peters NS, Davies DW, Kanagaratnam Pet al., 2015, Haemorrhagic cerebral air embolism from an atrio-oesophageal fistula following atrial fibrillation ablation, PERFUSION-UK, Vol: 30, Pages: 484-486, ISSN: 0267-6591

JOURNAL ARTICLE

Luther V, Jamil-Copley S, Koa-Wing M, Shun-Shin M, Hayat S, Linton NW, Lim PB, Whinnett Z, Wright IJ, Lefroy D, Peters NS, Davies DW, Kanagaratnam Pet al., 2015, Non-randomised comparison of acute and long-term outcomes of robotic versus manual ventricular tachycardia ablation in a single centre ischemic cohort, JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, Vol: 43, Pages: 175-185, ISSN: 1383-875X

JOURNAL ARTICLE

Jamil-Copley S, Vergara P, Carbucicchio C, Linton N, Koa-Wing M, Luther V, Francis DP, Peters NS, Davies DW, Tondo C, Della Bella P, Kanagaratnam Pet al., 2015, Application of Ripple Mapping to Visualize Slow Conduction Channels Within the Infarct-Related Left Ventricular Scar, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 8, Pages: 76-U110, ISSN: 1941-3149

JOURNAL ARTICLE

Jamil-Copley SJ, Linton NL, Koa-Wing MK, Vergara PV, Carbucicchio CC, Whinnett ZW, Lim PB, Davies DW, Peters NS, Tondo CT, Della Bella PD, Kanagaratnam PKet al., 2014, 3Development of a novel mapping system to visualise activation in ventricular scar., Europace, Vol: 16 Suppl 3

Ventricular scar is characterised by fractionated electrograms (egm) and not well displayed by current 3D mapping systems. We hypothesised that displaying intracardiac egms on 3D geometry as dynamic bars changing height according to the voltage-time relationship relative to a fiduciary egm, would enable visualisation slow conduction channels (SCC) in the infarct scar.

JOURNAL ARTICLE

Luther V, Jamil-Copley S, Shun-Shin M, Koa-Wing M, Wright I, Hayat S, Linton N, Lim PB, Lefroy D, Whinnett Z, Davies DW, Peters NS, Kanagaratnam Pet al., 2014, 24Acute and long-term outcomes for patients undergoing radiofrequency catheter ablation of scar-related ventricular tachycardia by robotic catheter navigation., Europace, Vol: 16 Suppl 3

Robotically-guided ablation offers theoretical advantages with greater catheter stability that can improve lesion depth. We performed a non-randomised comparison of patients undergoing ventricular tachycardia (VT) ablation either manually or using the Hansen robotic system.

JOURNAL ARTICLE

Jamil-Copley S, Bokan R, Kojodjojo P, Qureshi N, Koa-Wing M, Hayat S, Kyriacou A, Sandler B, Sohaib A, Wright I, Davies DW, Whinnett Z, Peters NS, Kanagaratnam P, Lim PBet al., 2014, Noninvasive electrocardiographic mapping to guide ablation of outflow tract ventricular arrhythmias, HEART RHYTHM, Vol: 11, Pages: 587-594, ISSN: 1547-5271

JOURNAL ARTICLE

Jamil-Copley S, Linton N, Koa-Wing M, Kojodjojo P, Lim PB, Malcolme-Lawes L, Whinnett Z, Wright I, Davies W, Peters N, Francis DP, Kanagaratnam Pet al., 2013, Application of Ripple Mapping with an Electroanatomic Mapping System for Diagnosis of Atrial Tachycardias, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Vol: 24, Pages: 1361-1369, ISSN: 1045-3873

JOURNAL ARTICLE

Malcolme-Lawes LC, Lim PB, Wright I, Kojodjojo P, Koa-Wing M, Jamil-Copley S, Dehbi H-M, Francis DP, Davies DW, Peters NS, Kanagaratnam Pet al., 2013, Characterization of the Left Atrial Neural Network and its Impact on Autonomic Modification Procedures, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 6, Pages: 632-640, ISSN: 1941-3149

JOURNAL ARTICLE

Barakat MF, Chehab O, Hayat S, Kelshiker M, Turner H, Norrington K, Konstantinou K, Whinnett Z, Koa-Wing M, Manisty C, Wright I, Jamil-Copley S, Lim B, Sutaria N, Nihoyannopoulos P, Lefroy D, Mayet J, Francis DP, Davies DW, Peters N, Kanagaratnam P, Okonko DOet al., 2013, ATTENUATIONS IN TISSUE DOPPLER-DERIVED LEFT VENTRICULAR SYSTOLIC VELOCITY PREDICT AN AMPLIFIED RISK OF LETHAL ARRHYTHMIAS IN ICD RECIPIENTS INDEPENDENTLY OF EJECTION FRACTION, 62nd Annual Scientific Session of the American-College-of-Cardiology, Publisher: ELSEVIER SCIENCE INC, Pages: E818-E818, ISSN: 0735-1097

CONFERENCE PAPER

Grapsa J, Koa-Wing M, Fox KF, 2013, Fiddling with the pacemaker: Twiddler's syndrome in a parkinsonian patient, PERFUSION-UK, Vol: 28, Pages: 31-33, ISSN: 0267-6591

JOURNAL ARTICLE

Malcolme-Lawes LC, Lim PB, Koa-Wing M, Whinnett ZI, Jamil-Copley S, Hayat S, Francis DP, Kojodjojo P, Davies DW, Peters NS, Kanagaratnam Pet al., 2013, Robotic assistance and general anaesthesia improve catheter stability and increase signal attenuation during atrial fibrillation ablation, EUROPACE, Vol: 15, Pages: 41-47, ISSN: 1099-5129

JOURNAL ARTICLE

Norrington KD, Turner HK, Barakat MF, Konstantinou K, Kelshikir M, O'Driscoll S, Screeche-Powelll C, Chilcott J, Hayat S, Koa-Wing M, Graspa J, Nihovannopoulos P, Manisty C, Fox K, Connolly S, Chapman N, Sutaria N, Kanagaratnam P, Mayet J, Francis DP, Okonko DOet al., 2012, Prognostic Utility of the Hemoglobin/Hematocrit Equation for Estimating Plasma Volume Changes During Hospitalization for Acute Decompensated Heart Failure, CIRCULATION, Vol: 126, ISSN: 0009-7322

JOURNAL ARTICLE

Malcolme-Lawes L, Lim PB, Wright I, Kojodjojo P, Koa-Wing M, Jamil-Copley S, Peters NS, Davies DW, Kanagaratnam Pet al., 2012, THE ROLE OF THE NEURAL NETWORKS IN IDENTIFICATION AND ABLATION OF PULMONARY VEIN ECTOPIC TRIGGERS, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A30-A30, ISSN: 1355-6037

CONFERENCE PAPER

Raphael CE, Koa-Wing M, Stain N, Wright I, Francis DP, Kanagaratnam Pet al., 2011, Implantable Cardioverter-Defibrillator Recipient Attitudes towards Device Deactivation: How Much do Patients Want to Know?, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, Vol: 34, Pages: 1628-1633, ISSN: 0147-8389

JOURNAL ARTICLE

Lim PB, Malcolme-Lawes LC, Stuber T, Koa-Wing M, Wright IJ, Tillin T, Sutton R, Davies DW, Peters NS, Francis DP, Kanagaratnam Pet al., 2011, Feasibility of multiple short, 40-s, intra-procedural ECG recordings to detect immediate changes in heart rate variability during catheter ablation for arrhythmias, JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, Vol: 32, Pages: 163-171, ISSN: 1383-875X

JOURNAL ARTICLE

Koa-Wing M, Kojodjojo P, Malcolme-Lawes LC, Salukhe TV, Linton NWF, Grogan AP, Bergman D, Lim PB, Whinnett ZI, McCarthy K, Ho SY, O'Neill MD, Peters NS, Davies DW, Kanagaratnam Pet al., 2009, Robotically Assisted Ablation Produces More Rapid and Greater Signal Attenuation Than Manual Ablation, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Vol: 20, Pages: 1398-1404, ISSN: 1045-3873

JOURNAL ARTICLE

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: respub-action=search.html&id=00447911&limit=30&person=true