Maksym V. Kopanitsa was born and educated in Ukraine. He graduated from the Odessa State University and received his PhD in Biophysics at the Bogomoletz Institute of Physiology (Kyiv, Ukraine), where he carried out research on pharmacology of voltage- and ligand-gated ion channels and synaptic transmission. During his post-doctoral appointments at the University of Dundee (2003–2004) and the Wellcome Trust Sanger Institute in Cambridge, UK (2004–2010), Maksym worked with genetically altered mice to study genetic regulation of synaptic transmission in brain slices.
In 2010–2018, Maksym Kopanitsa held industrial positions at preclinical CROs Synome Ltd (Cambridge, UK) and Charles River Discovery (Kuopio, Finland). In his capacity of Chief Operating Officer (Synome) and Head of Translational Biology (Charles River), Maksym supervised studies of rodent brain slice electrophysiology and behaviour in a wide range of neurodegenerative disease models for industrial clients and academic collaborations within several EU FP7 consortia.
In 2018, Maksym joined the UK Dementia Research Institute (DRI) at Imperial College London where he will collaborate with DRI fellows in the application of their fundamental research discoveries to preclinical models of neurodegenerative conditions.
et al., 2018, Impaired performance of the Q175 mouse model of Huntington’s disease in the touch screen paired associates learning task, Frontiers in Behavioral Neuroscience, Vol:12, ISSN:1662-5153
et al., 2018, Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95, European Journal of Neuroscience, Vol:47, ISSN:0953-816X, Pages:164-176
et al., 2017, Arc requires PSD95 for assembly into postsynaptic complexes involved with neural dysfunction and intelligence, Cell Reports, Vol:21, ISSN:2211-1247, Pages:679-691
et al., 2017, Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition, PLOS Genetics, Vol:13, ISSN:1553-7390
et al., 2017, Acquisition and reversal of visual discrimination learning in APPSwDI/Nos2-/-(CVN) mice., Neuroscience Letters, Vol:650, ISSN:0304-3940, Pages:126-133
et al., 2016, Reciprocal effects on neurocognitive and metabolic phenotypes in mouse models of 16p11.2 deletion and duplication syndromes, PLOS Genetics, Vol:12, ISSN:1553-7390
et al., 2013, Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior., Nat Neurosci, Vol:16, Pages:25-32