Dr Marina Kuimova received a M.Sc. in Chemistry from Moscow State University in 2001, and a Ph.D from Nottingham University in 2005. She is currently a Reader (Associate Professor) in the Department of Chemistry.
My research interests include elucidation of biologically relevant processes using different types of fluorescence imaging and time-resolved spectroscopy. The detailed description of my research activities can be found here
The popular article and the video clip where I talk to the media can be found here.
For a bit of fun, read the NatureChem 'The Sceptical Chymist' blog entry here
We are always looking to recruit talented and dedicated scientists. If you are interested in joining the group, please get in touch! It is likely that the funding for one or more PhD projects will be available for the 2017/2018 start date.
Prospective PhD students please make note of the President's PhD Scholarship Scheme
Funded positions will be advertised here when available:
NEW!! A PDRA position in PLIM probes:
Applications are invited for a postdoctoral position in my group, in collaboration with Prof Ramon Vilar and Dr Jean-Baptise Vannier, working on the development of phosphorescence lifetime imaging (PLIM) probes for DNA G-quadruplexes. Please check the jobs.ac.uk advert here.
Two PDRA positions are available:
Applications are invited for two postdoctoral positions in my group, in collaboration with Prof Ramon Vilar and Dr Jean-Baptise Vannier, working on the development of novel probes for DNA G-quadruplexes. Please check the jobs.ac.uk adverts for the research associate positions in the Synthesis of Optical Probes and in Optical Spectroscopy and Imaging
One DTC PhD studentship is available:
Applications are invited for an Medical Imaging CDT fully funded MRes+PhD studentship for a 2017/18 start. Please check our studentship Novel probes to correlate microscopic and macroscopic tumour structures (collaboration with Dr Gilbert Fruhwirth).
Our bid for Imperial Excellence Fund for Frontier Research in collaboration with Prof Ramon Vilar and Dr Jean-Baptiste Vannier was successful! Read about 'Searching for DNA quadruplexes' here.
Thanos Athanasiadis has successfully defended his PhD Thesis. Congratulations to Thanos!
Mike Dent has successfully defended his PhD Thesis. Congratulations to Mike!
Aurimas has successfully defended his PhD Thesis. He has also started an EPSRC Doctoral Prize Fellowship in the group on the 1st October. Congratulations to Aurimas!
Marketa Kubankova won the best talk prize in the Imaging, Sensing and Analytical Chemistry Section' of the final year postgraduate symposium at Imperial. Congratulations to Marketa!
Our new paper entitled 'Direct imaging of changes in aerosol particle viscosity upon hydration and chemical aging' has appeared in Chemical Science. Here we report imaging of microscopic viscosity in model atmospheric aerosols.
Our new paper entitled 'Unravelling the effect of temperature on viscosity-sensitive fluorescent molecular rotors' has appeared in Chemical Science. Here we report simultaneous imaging of viscosity and temperature using a single fluorophore.
Also please read about a red-emitting BODIPY-based temperature sensor, working via FLIM, here
Our new paper entitled 'Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors' has appeared in PCCP. Check it out for comparison between molecular rotors, FCS and MD simulations to calculate the viscosity of membranes. Congratulations to Mike and Ismael!
Aurimas Vysniauskas won the best talk prize in the 'Physical and Analytical Section' of the final year postgraduate symposium at Imperial. Congratulations to Aurimas!
N. A. Hosny et al Direct imaging of changes in aerosol particle viscosity upon hydration and chemical aging, Chem. Sci., 2016, 7, 1357-1367
T.T. Vu et al Tuning BODIPY molecular rotors into the red: sensitivity to viscosity vs temperature, J. Mater. Chem. C, 2016, 4, 2828 - 2833
A. Shivalingam, et al The interactions between a small molecule and G-quadruplexes are visualised by fluorescence lifetime imaging microscopy. Nature Commun., 2015, 6, 8178
A. Vysniauskas et al Unravelling the effect of temperature on viscosity-sensitive fluorescent molecular rotors, Chem Sci., 2015, DOI: 10.1039/C5SC02248G
I. Lopez-Duarte, T. T. Vu, et al A molecular rotor for measuring viscosity in plasma membranes of live cells, Chem. Commun., 2014, DOI: 10.1039/C3CC47530A (Emerging investigators issue)
Neveen A. Hosny et al Mapping microbubble viscosity using fluorescence lifetime imaging of molecular rotors, PNAS, 2013
M.K. Kuimova Mapping viscosity in cells using molecular rotors, PCCP, 2012, 14, 12671-12686
M. K. Kuimova, S. W. Botchway, A. W. Parker, M. Balaz, H. A. Collins, H. L. Anderson, K. Suhling, P. R. Ogilby, Imaging Intracellular Viscosity of a Single Cell During Photoinduced Cell Death, Nature Chem., 2009, 1, 69
et al., 2017, Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles., Biomaterials, Vol:113, Pages:105-117
et al., 2017, Measurement of the Raman spectra and hygroscopicity of four pharmaceutical aerosols as they travel from pressurised metered dose inhalers (pMDI) to a model lung, International Journal of Pharmaceutics, Vol:520, ISSN:0378-5173, Pages:59-69
et al., 2017, Probing supramolecular protein assembly using covalently attached fluorescent molecular rotors., Biomaterials, Vol:139, Pages:195-201
et al., 2017, Visualising the membrane viscosity of porcine eye lens cells using molecular rotors, Chemical Science, Vol:8, ISSN:2041-6520, Pages:3523-3528
et al., 2017, Imaging tumor microscopic viscosity in vivo using molecular rotors, Scientific Reports, Vol:7, ISSN:2045-2322