Imperial College London

Dr Maria Kyrgiou

Faculty of MedicineDepartment of Surgery & Cancer

Clinical Senior Lecturer in Gynaecological Oncology
 
 
 
//

Contact

 

+44 (0)20 7594 2177m.kyrgiou Website

 
 
//

Location

 

Institute of Reproductive and Developmental BiologyHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

141 results found

Paraskevaidi M, Morais CLM, Raglan O, Lima KMG, Paraskevaidis E, Martin-Hirsch PL, Kyrgiou M, Martin FLet al., 2018, Aluminium foil as an alternative substrate for the spectroscopic interrogation of endometrial cancer., J Biophotonics

Biospectroscopy has the potential to investigate and characterize biological samples and could, therefore, be utilized to diagnose various diseases in a clinical environment. An important consideration in spectrochemical studies is the cost-effectiveness of the substrate used to support the sample, as high expense would limit their translation into clinic. In this paper, the performance of low-cost aluminium (Al) foil substrates was compared with the commonly used low-emissivity (low-E) slides. Attenuated total reflection-Fourier transform infrared spectroscopy was used to analyse blood plasma and serum samples from women with endometrial cancer and healthy controls. The 2 populations were differentiated using principal component analysis with support vector machines with 100% sensitivity in plasma samples (endometrial cancer = 70; healthy controls = 15) using both Al foil and low-E slides as substrates. The same sensitivity results (100%) were achieved for serum samples (endometrial cancer = 60; healthy controls = 15). Specificity was found higher using Al foil (90%) in comparison to low-E slides (85%) and lower using Al foil (70%) in comparison to low-E slides in serum samples. The establishment of Al foil as low-cost and highly performing substrate would pave the way for large-scale, multicentre studies and potentially for routine clinical use.

JOURNAL ARTICLE

Tainio K, Athanasiou A, Tikkinen KAO, Aaltonen R, Cardenas Hernandes J, Glazer-Livson S, Jakobsson M, Joronen K, Kiviharju M, Louvanto K, Oksjoki S, Tahtinen R, Virtanen S, Nieminen P, Kyrgiou M, Kalliala Iet al., 2018, Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis, BMJ-BRITISH MEDICAL JOURNAL, Vol: 360, ISSN: 1756-1833

JOURNAL ARTICLE

Arbyn M, Charles R, Verdoodt F, Kyrgiou M, Tzafetas M, Ghaem-Maghami S, Petry KU, Leeson S, Bergeron C, Nieminen P, Gondry J, Reich O, Moss Eet al., 2017, PREDICTION OF THE OUTCOME AFTER EXCISION OF CERVICAL PRECANCER BY THE RESECTION MARGINS OR BY POST-TREATMENT HPV TESTING: A SYSTEMATIC REVIEW AND META-ANALYSIS, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 1910-1910, ISSN: 1048-891X

CONFERENCE PAPER

Arbyn M, Redman CWE, Verdoodt F, Kyrgiou M, Tzafetas M, Ghaem-Maghami S, Petry K-U, Leeson S, Bergeron C, Nieminen P, Gondry J, Reich O, Moss ELet al., 2017, Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis, LANCET ONCOLOGY, Vol: 18, Pages: 1665-1679, ISSN: 1470-2045

JOURNAL ARTICLE

Domenici L, Nixon K, Sorbi F, Kyrgiou M, Yazbek J, Hall M, Campbell J, Gibbons N, Park W-HE, Gabra H, Fotopoulou Cet al., 2017, Surgery for Recurrent Uterine Cancer: Surgical Outcomes and Implications for SurvivalA Case Series, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 27, Pages: 759-767, ISSN: 1048-891X

JOURNAL ARTICLE

Halliwell DE, Morais CLM, Lima KMG, Trevisan J, Siggel-King MRF, Craig T, Ingham J, Martin DS, Heys K, Kyrgiou M, Mitra A, Paraskevaidis E, Theophilou G, Martin-Hirsch PL, Cricenti A, Luce M, Weightman P, Martin FLet al., 2017, An imaging dataset of cervical cells using scanning near-field optical microscopy coupled to an infrared free electron laser, SCIENTIFIC DATA, Vol: 4, ISSN: 2052-4463

JOURNAL ARTICLE

Kalliala I, Markozannes G, Gunter MJ, Paraskevaidis E, Gabra H, Mitra A, Terzidou V, Bennett P, Martin-Hirsch P, Tsilidis KK, Kyrgiou Met al., 2017, Obesity and gynaecological and obstetric conditions: umbrella review of the literature, BMJ-BRITISH MEDICAL JOURNAL, Vol: 359, ISSN: 1756-1833

JOURNAL ARTICLE

Kottaridi C, Kyrgiou M, Pouliakis A, Magkana M, Aga E, Spathis A, Mitra A, Makris G, Chrelias C, Mpakou V, Paraskevaidis E, Panayiotides JG, Karakitsos Pet al., 2017, Quantitative Measurement of L1 Human Papillomavirus Type 16 Methylation for the Prediction of Preinvasive and Invasive Cervical Disease, JOURNAL OF INFECTIOUS DISEASES, Vol: 215, Pages: 764-771, ISSN: 0022-1899

JOURNAL ARTICLE

Kyrgiou M, Athanasiou A, Kalliala IEJ, Paraskevaidi M, Mitra A, Martin-Hirsch PPL, Arbyn M, Bennett P, Paraskevaidis Eet al., 2017, Obstetric outcomes after conservative treatment for cervical intraepithelial lesions and early invasive disease, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

JOURNAL ARTICLE

Kyrgiou M, Bennett P, 2017, Can we prevent preterm birth after radical trachelectomy?, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 124, Pages: 1737-1737, ISSN: 1470-0328

JOURNAL ARTICLE

Kyrgiou M, Kalliala I, Markozannes G, Gunter MJ, Paraskevaidis E, Gabra H, Martin-Hirsch P, Tsilidis KKet al., 2017, Adiposity and cancer at major anatomical sites: umbrella review of the literature, BMJ-BRITISH MEDICAL JOURNAL, Vol: 356, ISSN: 1756-1833

JOURNAL ARTICLE

Kyrgiou M, Kalliala I, Mitra A, Ng KYB, Raglan O, Fotopoulou C, Martin-Hirsch P, Paraskevaidis E, Arbyn Met al., 2017, Immediate referral to colposcopy versus cytological surveillance for low-grade cervical cytological abnormalities in the absence of HPV test: A systematic review and a meta-analysis of the literature, INTERNATIONAL JOURNAL OF CANCER, Vol: 140, Pages: 216-223, ISSN: 0020-7136

JOURNAL ARTICLE

Kyrgiou M, Kalliala IEJ, Mitra A, Fotopoulou C, Ghaem-Maghami S, Martin-Hirsch PPL, Cruickshank M, Arbyn M, Paraskevaidis Eet al., 2017, Immediate referral to colposcopy versus cytological surveillance for minor cervical cytological abnormalities in the absence of HPV test, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

JOURNAL ARTICLE

Kyrgiou M, Mitra A, Moscicki A-B, 2017, Does the vaginal microbiota play a role in the development of cervical cancer?, TRANSLATIONAL RESEARCH, Vol: 179, Pages: 168-182, ISSN: 1931-5244

JOURNAL ARTICLE

Mitra A, MacIntyre D, Lai J, Lee Y, Smith A, Marchesi J, Lyons D, Bennett P, Kyrgiou Met al., 2017, The Impact of Excisional Treatment for Cervical Intraepithelial Neoplasia on the Vaginal Microbiota., 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Publisher: SAGE PUBLICATIONS INC, Pages: 89A-89A, ISSN: 1933-7191

CONFERENCE PAPER

Mitra A, MacIntyre D, Lee Y, Smith A, Marchesi J, Lyons D, Bennett P, Kyrgiou Met al., 2017, THE VAGINAL MICROBIOTA AFTER EXCISIONAL TREATMENT FOR CERVICAL INTRAEPITHELIAL NEOPLASIA, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 979-979, ISSN: 1048-891X

CONFERENCE PAPER

Mitra A, MacIntyre DA, Mahajan V, Lee YS, Smith A, Marchesi JR, Lyons D, Bennett PR, Kyrgiou Met al., 2017, Comparison of vaginal microbiota sampling techniques: cytobrush versus swab, SCIENTIFIC REPORTS, Vol: 7, ISSN: 2045-2322

JOURNAL ARTICLE

Nasser S, Kyrgiou M, Krell J, Haidopoulos D, Bristow R, Fotopoulou Cet al., 2017, A Review of Thoracic and Mediastinal Cytoreductive Techniques in Advanced Ovarian Cancer: Extending the Boundaries, ANNALS OF SURGICAL ONCOLOGY, Vol: 24, Pages: 3700-3705, ISSN: 1068-9265

JOURNAL ARTICLE

Paraskevaidi M, Martin-Hirsch PL, Kyrgiou M, Martin FLet al., 2017, Underlying role of mitochondrial mutagenesis in the pathogenesis of a disease and current approaches for translational research, MUTAGENESIS, Vol: 32, Pages: 335-342, ISSN: 0267-8357

JOURNAL ARTICLE

Paraskevaidi M, Morais CLM, Raglan O, Lima KMG, Martin-Hirsch PL, Paraskevaidis E, Kyrgiou M, Martin FLet al., 2017, Spectroscopy of blood samples for the diagnosis of endometrial cancer and classification of its different subtypes., Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Publisher: AMER SOC CLINICAL ONCOLOGY, ISSN: 0732-183X

CONFERENCE PAPER

Raglan O, Doria L, Soares R, Rosini F, Farrokh-Eslamlou T, McKenzie J, Takats Z, Kyrgiou Met al., 2017, ENDOMETRIAL CANCER TISSUE HAS A UNIQUE PHOSPHOLIPID SIGNATURE IDENTIFIABLE USING DESORPTION ELECTROSPRAY IONISATION (DESI) IMAGING, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 1195-1195, ISSN: 1048-891X

CONFERENCE PAPER

Raglan O, Doria L, Soares R, Rosini F, Farrokh-Eslamlou T, McKenzie J, Takats Z, Kyrgiou Met al., 2017, ENDOMETRIAL CANCER TISSUE HAS A UNIQUE PHOSPHOLIPID SIGNATURE IDENTIFIABLE USING DESORPTION ELECTROSPRAY IONISATION (DESI) IMAGING, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 454-454, ISSN: 1048-891X

CONFERENCE PAPER

Tainio K, Athanasiou A, Tikkinen K, Aaltonen R, Cardenas Hernandes L, Glazer-Livson S, Jakobsson M, Joronen K, Kiviharju M, Louvanto K, Oksjoki S, Tahtinen R, Virtanen S, Nieminen P, Kyrgiou M, Kalliala Iet al., 2017, Y NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 2 UNDER ACTIVE SURVEILLANCE - A SYSTEMATIC REVIEW AND META-ANALYSIS, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 893-893, ISSN: 1048-891X

CONFERENCE PAPER

Tainio K, Athanasiou A, Tikkinen K, Aaltonen R, Cardenas Hernandes L, Glazer-Livson S, Jakobsson M, Joronen K, Kiviharju M, Louvanto K, Oksjoki S, Tahtinen R, Virtanen S, Nieminen P, Kyrgiou M, Kalliala Iet al., 2017, NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 2 UNDER ACTIVE SURVEILLANCE - A SYSTEMATIC REVIEW AND META-ANALYSIS, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 25-25, ISSN: 1048-891X

CONFERENCE PAPER

Farthing A, Kyrgiou M, 2016, Re: Laparoscopic radical abdominal trachelectomy for the management of stage IB1 cervical cancer at 14 weeks gestation: case report and review of the literature Reply, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 123, Pages: 646-646, ISSN: 1470-0328

JOURNAL ARTICLE

Fotopoulou C, Jones BP, Savvatis K, Campbell J, Kyrgiou M, Farthing A, Brett S, Roux R, Hall M, Rustin G, Gabra H, Jiao L, Stumpfle Ret al., 2016, Maximal effort cytoreductive surgery for disseminated ovarian cancer in a UK setting: challenges and possibilities, ARCHIVES OF GYNECOLOGY AND OBSTETRICS, Vol: 294, Pages: 607-614, ISSN: 0932-0067

JOURNAL ARTICLE

Halliwell DE, Kyrgiou M, Mitra A, Kalliala I, Paraskevaidis E, Theophilou G, Martin-Hirsch PL, Martin FLet al., 2016, Tracking the Impact of Excisional Cervical Treatment on the Cervix using Biospectroscopy, SCIENTIFIC REPORTS, Vol: 6, ISSN: 2045-2322

JOURNAL ARTICLE

Halliwell DE, Morais CLM, Lima KMG, Trevisan J, Siggel-King MRF, Craig T, Ingham J, Martin DS, Heys KA, Kyrgiou M, Mitra A, Paraskevaidis E, Theophilou G, Martin-Hirsch PL, Cricenti A, Luce M, Weightman P, Martin FLet al., 2016, Imaging cervical cytology with scanning near-field optical microscopy (SNOM) coupled with an IR-FEL, SCIENTIFIC REPORTS, Vol: 6, ISSN: 2045-2322

JOURNAL ARTICLE

Kalliala I, Tsilidis K, Kyrgiou M, 2016, Obesity and Gynaecological Cancer - An Umbrella Review and Meta-Analysis., 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation, Publisher: SAGE PUBLICATIONS INC, Pages: 179A-179A, ISSN: 1933-7191

CONFERENCE PAPER

Kindinger LM, Kyrgiou M, MacIntyre DA, Cacciatore S, Yulia A, Cook J, Terzidou V, Teoh TG, Bennett PRet al., 2016, Preterm Birth Prevention Post-Conization: A Model of Cervical Length Screening with Targeted Cerclage, PLOS ONE, Vol: 11, ISSN: 1932-6203

JOURNAL ARTICLE

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: respub-action=search.html&id=00704355&limit=30&person=true