Imperial College London

ProfessorMichaelLevin

Faculty of MedicineDepartment of Medicine

Chair in Paediatrics & International Child Health
 
 
 
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Contact

 

+44 (0)20 7594 3760m.levin

 
 
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Location

 

233Medical SchoolSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

195 results found

Gliddon HD, Howes PD, Kaforou M, Levin M, Stevens MMet al., 2016, A nucleic acid strand displacement system for the multiplexed detection of tuberculosis-specific mRNA using quantum dots, NANOSCALE, Vol: 8, Pages: 10087-10095, ISSN: 2040-3364

JOURNAL ARTICLE

Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-Lopez M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinon-Torres F, Burns JC, Coin LJM, Levin Met al., 2016, Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children, JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, Vol: 316, Pages: 835-845, ISSN: 0098-7484

JOURNAL ARTICLE

Levin M, Kaforou M, 2016, Predicting active tuberculosis progression by RNA analysis, LANCET, Vol: 387, Pages: 2268-2270, ISSN: 0140-6736

JOURNAL ARTICLE

Martinon-Torres F, Png E, Khor CC, Davila S, Wright VJ, Sim KS, Vega A, Fachal L, Inwald D, Nadel S, Carrol ED, Martinon-Torres N, Marcos Alonso S, Carracedo A, Morteruel E, Lopez-Bayon J, Concha Torre A, Calvo Monge C, Gonzalez de Aguilar PA, Esteban Torne E, del Carmen Martinez-Padilla M, Maria Martinon-Sanchez J, Levin M, Hibberd ML, Salas Aet al., 2016, Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies, SCIENTIFIC REPORTS, Vol: 6, ISSN: 2045-2322

JOURNAL ARTICLE

McDonald JU, Kaforou M, Clare S, Hale C, Ivanova M, Huntley D, Dorner M, Wright VJ, Levin M, Martinon-Torres F, Herberg JA, Tregoning JSet al., 2016, A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease, MSYSTEMS, Vol: 1, ISSN: 2379-5077

JOURNAL ARTICLE

Seaby EG, Wright VJ, Levin M, 2016, Genome-wide Association Studies in Infectious Diseases, PEDIATRIC INFECTIOUS DISEASE JOURNAL, Vol: 35, Pages: 802-804, ISSN: 0891-3668

JOURNAL ARTICLE

Shimizu C, Eleftherohorinou H, Wright VJ, Kim J, Alphonse MP, Perry JC, Cimaz R, Burgner D, Dahdah N, Hoang LT, Khor CC, Salgado A, Tremoulet AH, Davila S, Kuijpers TW, Hibberd ML, Johnson TA, Takahashi A, Tsunoda T, Kubo M, Tanaka T, Onouchi Y, Yeung RSM, Coin LJM, Levin M, Burns JCet al., 2016, Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated With Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities, CIRCULATION-CARDIOVASCULAR GENETICS, Vol: 9, Pages: 559-+, ISSN: 1942-325X

JOURNAL ARTICLE

Davies S, Sutton N, Blackstock S, Gormley S, Hoggart CJ, Levin M, Herberg JAet al., 2015, Predicting IVIG resistance in UK Kawasaki disease, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 100, Pages: 366-368, ISSN: 0003-9888

JOURNAL ARTICLE

Eleftheriou D, Levin M, Shingadia D, Tulloh R, Klein N, Brogan Pet al., 2015, Authors' response to 'Aspirin dose for treatment of Kawasaki disease', ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 100, ISSN: 0003-9888

JOURNAL ARTICLE

Evans C, Orf K, Horvath E, Levin M, De La Fuente J, Chakravorty S, Cunnington AJet al., 2015, Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1, HAEMATOLOGICA, Vol: 100, Pages: 1508-1516, ISSN: 0390-6078

JOURNAL ARTICLE

George EC, Walker AS, Kiguli S, Olupot-Olupot P, Opoka RO, Engoru C, Akech SO, Nyeko R, Mtove G, Reyburn H, Berkley JA, Mpoya A, Levin M, Crawley J, Gibb DM, Maitland K, Babiker AGet al., 2015, Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score, BMC MEDICINE, Vol: 13, ISSN: 1741-7015

JOURNAL ARTICLE

Kiguli S, Maitland K, George EC, Olupot-Olupot P, Opoka RO, Engoru C, Akech SO, Nyeko R, Mtove G, Reyburn H, Levin M, Babiker AG, Gibb DM, Crawley Jet al., 2015, Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness, BMC MEDICINE, Vol: 13, ISSN: 1741-7015

JOURNAL ARTICLE

Nicol MP, Gnanashanmugam D, Browning R, Click ES, Cuevas LE, Detjen A, Graham SM, Levin M, Makhene M, Nahid P, Perez-Velez CM, Reither K, Song R, Spiegel HML, Worrell C, Zar HJ, Walzl Get al., 2015, A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis, CLINICAL INFECTIOUS DISEASES, Vol: 61, Pages: S164-S172, ISSN: 1058-4838

JOURNAL ARTICLE

Shah V, Christov G, Mukasa T, Brogan KS, Wade A, Eleftheriou D, Levin M, Tulloh RM, Almeida B, Dillon MJ, Marek J, Klein N, Brogan PAet al., 2015, Cardiovascular status after Kawasaki disease in the UK, HEART, Vol: 101, Pages: 1646-1655, ISSN: 1355-6037

JOURNAL ARTICLE

von Both U, Kaforou M, Levin M, Newton SMet al., 2015, Understanding immune protection against tuberculosis using RNA expression profiling, VACCINE, Vol: 33, Pages: 5289-5293, ISSN: 0264-410X

JOURNAL ARTICLE

Anderson ST, Kaforou M, Brent AJ, Wright VJ, Banwell CM, Chagaluka G, Crampin AC, Dockrell HM, French N, Hamilton MS, Hibberd ML, Kern F, Langford PR, Ling L, Mlotha R, Ottenhoff THM, Pienaar S, Pillay V, Scott JAG, Twahir H, Wilkinson RJ, Coin LJ, Heyderman RS, Levin M, Eley Bet al., 2014, Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 370, Pages: 1712-1723, ISSN: 0028-4793

JOURNAL ARTICLE

Carpenter D, Taype C, Goulding J, Levin M, Eley B, Anderson S, Shaw M-A, Armour JALet al., 2014, CCL3L1 copy number, CCR5 genotype and susceptibility to tuberculosis, BMC MEDICAL GENETICS, Vol: 15, ISSN: 1471-2350

JOURNAL ARTICLE

Eleftheriou D, Levin M, Shingadia D, Tulloh R, Klein NJ, Brogan PAet al., 2014, Management of Kawasaki disease, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 99, Pages: 74-83, ISSN: 0003-9888

JOURNAL ARTICLE

Eleftheriou D, Levin M, Shingadia D, Tulloh R, Klein NJ, Brogan PAet al., 2014, Management of Kawasaki disease, ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, Vol: 99, Pages: 74-83, ISSN: 1359-2998

JOURNAL ARTICLE

Hoang LT, Shimizu C, Ling L, Naim ANM, Khor CC, Tremoulet AH, Wright V, Levin M, Hibberd ML, Burns JCet al., 2014, Global gene expression profiling identifies new therapeutic targets in acute Kawasaki disease, GENOME MEDICINE, Vol: 6, ISSN: 1756-994X

JOURNAL ARTICLE

Kaforou M, Wright VJ, Levin M, 2014, Host RNA signatures for diagnostics: An example from paediatric tuberculosis in Africa, JOURNAL OF INFECTION, Vol: 69, Pages: S28-S31, ISSN: 0163-4453

JOURNAL ARTICLE

Levin M, Burgner D, 2014, Treatment of Kawasaki disease with anti-TNF antibodies, LANCET, Vol: 383, Pages: 1700-1703, ISSN: 0140-6736

JOURNAL ARTICLE

Levin M, Burns JC, Gordon JB, 2014, Warfarin plus Aspirin or Aspirin Alone for with Giant Coronary Artery Aneurysms Secondary to Kawasaki Disease?, CARDIOLOGY, Vol: 129, Pages: 174-177, ISSN: 0008-6312

JOURNAL ARTICLE

Zenz W, Klobassa DS, Sonnleitner A, Binder A, Sellner A, Sperl M, Wintergerst U, Huemer C, Ausserer B, Stelzl W, Kaulfersch W, Grigorow I, Biebl A, Wimmer A, Ortner D, Emhofer J, Birnbacher R, Mostafa G, Ihm U, Keck B, Farr S, Jaros Z, Zaunschirm HA, Weingarten C, Glennie L, van Leeuwen E, Levin Met al., 2014, Genetic research in Austrian children. Balancing act between milestones in medicine and millstones in bureaucracy, MONATSSCHRIFT KINDERHEILKUNDE, Vol: 162, Pages: 1110-1116, ISSN: 0026-9298

JOURNAL ARTICLE

Chang C-J, Kuo H-C, Chang J-S, Lee J-K, Tsai F-J, Khor CC, Chang L-C, Chen S-P, Ko T-M, Liu Y-M, Chen Y-J, Hong YM, Jang GY, Hibberd ML, Kuijpers T, Burgner D, Levin M, Burns JC, Davila S, Chen Y-T, Chen C-H, Wu J-Y, Lee Y-Cet al., 2013, Replication and Meta-Analysis of GWAS Identified Susceptibility Loci in Kawasaki Disease Confirm the Importance of B Lymphoid Tyrosine Kinase (BLK) in Disease Susceptibility, PLOS ONE, Vol: 8, ISSN: 1932-6203

JOURNAL ARTICLE

Couto-Alves A, Wright VJ, Perumal K, Binder A, Carrol ED, Emonts M, de Groot R, Hazelzet J, Kuijpers T, Nadel S, Zenz W, Ramnarayan P, Levin M, Coin L, Inwald DPet al., 2013, A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis, CRITICAL CARE, Vol: 17, ISSN: 1466-609X

JOURNAL ARTICLE

Herberg JA, Kaforou M, Gormley S, Sumner ER, Patel S, Jones KDJ, Paulus S, Fink C, Martinon-Torres F, Montana G, Wright VJ, Levin Met al., 2013, Transcriptomic Profiling in Childhood H1N1/09 Influenza Reveals Reduced Expression of Protein Synthesis Genes, JOURNAL OF INFECTIOUS DISEASES, Vol: 208, Pages: 1664-1668, ISSN: 0022-1899

JOURNAL ARTICLE

Kaforou M, Wright VJ, Oni T, French N, Anderson ST, Bangani N, Banwell C, Brent AJ, Crampin AC, Dockrell HM, Eley B, Heyderman RS, Hibberd ML, Kern F, Langford PR, Ling L, Mendelson M, Ottenhoff TH, Zgambo F, Wilkinson RJ, Coin LJ, Levin Met al., 2013, Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study, PLOS MEDICINE, Vol: 10, ISSN: 1549-1676

JOURNAL ARTICLE

Levin M, 2013, Steroids for Kawasaki disease: the devil is in the detail, HEART, Vol: 99, Pages: 69-70, ISSN: 1355-6037

JOURNAL ARTICLE

Levin M, Kaforou M, Herberg J, Wright VJ, Coin LJMet al., 2013, METHOD FOR CALCULATING A DISEASE RISK SCORE, PCT/GB2013/050225

The present disclosure relates to a general method for converting complex gene expression data into a simple, composite disease risk score which can be used for the development of rapid diagnostic tests suitable for clinical use for the determination of the presence of an infection or disease in a host.

PATENT

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