Imperial College London
Portrait Picture

PROFESSOR MIRIAM F. MOFFATT

Faculty of Medicine, National Heart & Lung Institute

Consul for the Faculty of Medicine, Professor
 
 
 
//

Contact

 

+44 (0)20 7594 2942m.moffatt

 
 
//

Location

 

400Guy Scadding BuildingRoyal Brompton Campus

//

Summary

 

Publications

Publication Type
Year
to

305 results found

Loeser S, Zhang Y, Gregory L, Walker S, Dean C, Schaefer K, Denney L, Cookson WOC, Moffatt MF, Lloyd CMet al., 2014, Novel insights into the <i>in vivo</i> function of <i>Ormdl3</i> - a gene associated with the onset of childhood asthma, IMMUNOLOGY, Vol: 143, Pages: 59-59, ISSN: 0019-2805

Journal article

Zhang Y, Dean C, Chessum L, Dao N, Stewart M, Taylor M, Cookson WO, Moffatt MFet al., 2014, Functional analysis of a novel ENU-induced PHD finger 11 (<i>Phf11)</i> mouse mutant, MAMMALIAN GENOME, Vol: 25, Pages: 573-582, ISSN: 0938-8990

Journal article

Salter SJ, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, Turner P, Parkhill J, Loman NJ, Walker AWet al., 2014, Reagent and laboratory contamination can critically impact sequence-based microbiome analyses, BMC Biology, Vol: 12, ISSN: 1741-7007

BackgroundThe study of microbial communities has been revolutionised in recent years by the widespread adoption of culture independent analytical techniques such as 16S rRNA gene sequencing and metagenomics. One potential confounder of these sequence-based approaches is the presence of contamination in DNA extraction kits and other laboratory reagents.ResultsIn this study we demonstrate that contaminating DNA is ubiquitous in commonly used DNA extraction kits and other laboratory reagents, varies greatly in composition between different kits and kit batches, and that this contamination critically impacts results obtained from samples containing a low microbial biomass. Contamination impacts both PCR-based 16S rRNA gene surveys and shotgun metagenomics. We provide an extensive list of potential contaminating genera, and guidelines on how to mitigate the effects of contamination.ConclusionsThese results suggest that caution should be advised when applying sequence-based techniques to the study of microbiota present in low biomass environments. Concurrent sequencing of negative control samples is strongly advised.

Journal article

Molyneaux PL, Cox MJ, Willis-Owen SAG, Mallia P, Russell KE, Russel A-M, Murphy E, Johnston SL, Schwarte DA, Wells AU, Cookson WOC, Maher TM, Moffatt MFet al., 2014, The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis, American Journal of Respiratory and Critical Care Medicine, Vol: 190, Pages: 906-913, ISSN: 1535-4970

Rationale:Idiopathic pulmonaryfibrosis (IPF)isa progressivelung diseaseof unknown cause that leads to respiratory failure and death within 5 yearsof diagnosis. Overt respiratory infection and immunosuppression carrya high morbidity and mortality, and polymorphisms in genes related toepithelial integrity and host defense predispose to IPF.Objectives: To investigate the role of bacteria in the pathogenesisand progression of IPF.Methods: We prospectively enrolled patients diagnosed with IPFaccording to international criteria together with healthy smokers,nonsmokers, and subjectswithmoderate chronic obstructive pulmonarydisease as control subjects. Subjects underwent bronchoalveolarlavage (BAL), from which genomic DNA was isolated. The V3–V5region of the bacterial 16S rRNA gene was amplified, allowingquantification of bacterial load and identification of communities by 16SrRNA quantitative polymerase chain reaction and pyrosequencing. Measurements and Main Results: Sixty-five patients with IPFhad double the burden of bacteria in BAL fluid compared with 44 controlsubjects. Baseline bacterial burden predicted the rate of decline in lungvolume and risk of death and associated independently with thers35705950 polymorphism of the MUC5B mucin gene, a proven hostsusceptibilityfactorfor IPF. Sequencing yielded912,883 high-quality readsfrom all subjects.WeidentifiedHaemophilus, Streptococcus,Neisseria, andVeillonella spp. to be more abundant in cases than control subjects.Regression analyses indicated that these specific operational taxonomicunits as well as bacterial burden associated independently with IPF.Conclusions: IPF is characterized by an increased bacterial burdenin BAL that predicts decline in lung function and death. Trials ofantimicrobial therapy are needed to determine if microbial burdenis pathogenic in the disease.

Journal article

Dizier M-H, Margaritte-Jeannin P, Madore A-M, Moffatt M, Brossard M, Lavielle N, Sarnowski C, Just J, Cookson W, Lathrop M, Laprise C, Bouzigon E, Demenais Fet al., 2014, The nuclear factor I/A (<i>NFIA</i>) gene is associated with the asthma plus rhinitis phenotype, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 134, Pages: 576-+, ISSN: 0091-6749

Journal article

Salter, Susannah Cox, Michael J Turek, Elena M Calus, Szymon T Cookson, William O Moffatt, Miriam F Turner, Paul Parkhill, Julian Loman, Nick Walker, Alan Wet al., 2014, Reagent contamination can critically impact sequence-based microbiome analyses, bioRxiv

Susannah Salter1,7 (sb18{at}sanger.ac.uk), Michael J Cox2 (michael.cox1{at}imperial.ac.uk), Elena M Turek2 (elena.turek11{at}imperial.ac.uk), Szymon T Calus3 (s.t.calus{at}bham.ac.uk), William O Cookson2 (w.cookson{at}imperial.ac.uk), Miriam F Moffatt2 (m.moffatt{at}imperial.ac.uk), Paul Turner4 (pault{at}tropmedres.ac), Julian Parkhill5 (parkhill{at}sanger.ac.uk), Nick Loman3 (n.j.loman{at}bham.ac.uk) and Alan W Walker6 (alan.walker{at}abdn.ac.uk) 1 Wellcome Trust Sanger Institute; 2 Molecular Genetics and Genomics, National Heart and Lung Institute, Imperial College London; 3 Institute of Microbiology and Infection, University of Birmingham; 4 Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford; 5 Pathogen Genomics, Wellcome Trust Sanger Institute; 6 Microbiology Group, Rowett Institute of Nutrition and Health, University of Aberdeen ↵* Corresponding author; email: sb18{at}sanger.ac.uk AbstractThe study of microbial communities has been revolutionised in recent years by the widespread adoption of culture independent analytical techniques such as 16S rRNA gene sequencing and metagenomics. One potential confounder of these sequence-based approaches is the presence of contamination in DNA extraction kits and other laboratory reagents. In this study we demonstrate that contaminating DNA is ubiquitous in commonly used DNA extraction kits, varies greatly in composition between different kits and kit batches, and that this contamination critically impacts results obtained from samples containing a low microbial biomass. Contamination impacts both PCR-based 16S rRNA gene surveys and shotgun metagenomics. These results suggest that caution should be advised when applying sequence-based techniques to the study of microbiota present in low biomass environments. We provide an extensive list of potential contaminating genera, and guidelines on how to mitigate the effects of contamination. Concurrent sequencing of negative control samples i

Journal article

van der Valk RJP, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Moller E, Caceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, Nadif R, Ober C, Thompson EE, Estrada K, Hofman A, Uitterlinden AG, van Duijn C, Rivadeneira F, Li X, Eckel SP, Berhane K, Gauderman WJ, Granell R, Evans DM, St Pourcain B, McArdle W, Kemp JP, Smith GD, Tiesler CMT, Flexeder C, Simpson A, Murray CS, Fuchs O, Postma DS, Bonnelykke K, Torrent M, Andersson M, Sleiman P, Hakonarson H, Cookson WO, Moffatt MF, Paternoster L, Melen E, Sunyer J, Bisgaard H, Koppelman GH, Ege M, Custovic A, Heinrich J, Gilliland FD, Henderson AJ, Jaddoe VWV, de Jongste JCet al., 2014, Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 134, Pages: 46-55, ISSN: 0091-6749

Journal article

Ma B, Wilker EH, Willis-Owen SAG, Byun H-M, Wong KCC, Motta V, Baccarelli AA, Schwartz J, Cookson WOCM, Khabbaz K, Mittleman MA, Moffatt MF, Liang Let al., 2014, Predicting DNA methylation level across human tissues, NUCLEIC ACIDS RESEARCH, Vol: 42, Pages: 3515-3528, ISSN: 0305-1048

Journal article

Scholtens S, Postma DS, Moffatt MF, Panasevich S, Granell R, Henderson AJ, Melen E, Nyberg F, Pershagen G, Jarvis D, Ramasamy A, Wjst M, Svanes C, Bouzigon E, Demenais F, Kauffmann F, Siroux V, von Mutius E, Ege MJ, Braun-Fahrlaender C, Genuneit J, Brunekreef B, Smit HA, Wijga AH, Kerkhof M, Curjuric I, Imboden M, Thun GA, Probst-Hensch N, Freidin MB, Bragina EI, Deev IA, Puzyrev VP, Daley D, Park J, Becker A, Chan-Yeung M, Kozyrskyj AL, Pare P, Marenholz I, Lau S, Keil T, Lee Y-A, Kabesch M, Wijmenga C, Franke L, Nolte IM, Vonk J, Kumar A, Farrall M, Cookson WOCM, Strachan DP, Koppelman GH, Boezen HMet al., 2014, Novel childhood asthma genes interact with <i>in utero</i> and early-life tobacco smoke exposure, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 133, Pages: 885-888, ISSN: 0091-6749

Journal article

Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Liang L, Rodriguez E, Novak N, Kabesch M, Bradley M, McLean I, Cookson WO, Irvine AD, Moffatt MFet al., 2014, A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis, 41st Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Publisher: WILEY, Pages: E21-E21, ISSN: 0906-6705

Conference paper

Portelli MA, Siedlinski M, Stewart CE, Postma DS, Nieuwenhuis MA, Vonk JM, Nurnberg P, Altmuller J, Moffatt MF, Wardlaw AJ, Parker SG, Connolly MJ, Koppelman GH, Sayers Iet al., 2014, Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels, FASEB JOURNAL, Vol: 28, Pages: 923-934, ISSN: 0892-6638

Journal article

Peljto A, Selman M, Kim DS, Tucker L, Murphy E, Zhang W, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch DA, Groshong SD, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, Du Bois RM, Garcia CK, Devine M, Gudmundsson G, Isaksson H, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Pardo A, Crapo J, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Yang IV, Fingerlin T, Schwartz DAet al., 2014, Genetic Variants Associated With Pulmonary Fibrosis In Asian And Hispanic Populations, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Weidinger S, Willis-Owen SAG, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Foelster-Holst R, Franke A, Novak N, Fahy CM, Winge MCG, Kabesch M, Illig T, Heath S, Soderhall C, Melen E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, Mclean WHI, Brown SJ, Cookson WOC, Lathrop GM, Irvine AD, Moffatt MFet al., 2013, A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis, Human Molecular Genetics, Vol: 22, Pages: 4841-4856, ISSN: 0964-6906

Atopic dermatitis (AD) is the most common dermatological disease of childhood. Many children with AD have asthma and AD shares regions of genetic linkage with psoriasis, another chronic inflammatory skin disease. We present here a genome-wide association study (GWAS) of childhood-onset AD in 1563 European cases with known asthma status and 4054 European controls. Using Illumina genotyping followed by imputation, we generated 268 034 consensus genotypes and in excess of 2 million single nucleotide polymorphisms (SNPs) for analysis. Association signals were assessed for replication in a second panel of 2286 European cases and 3160 European controls. Four loci achieved genome-wide significance for AD and replicated consistently across all cohorts. These included the epidermal differentiation complex (EDC) on chromosome 1, the genomic region proximal to LRRC32 on chromosome 11, the RAD50/IL13 locus on chromosome 5 and the major histocompatibility complex (MHC) on chromosome 6; reflecting action of classical HLA alleles. We observed variation in the contribution towards co-morbid asthma for these regions of association. We further explored the genetic relationship between AD, asthma and psoriasis by examining previously identified susceptibility SNPs for these diseases. We found considerable overlap between AD and psoriasis together with variable coincidence between allergic rhinitis (AR) and asthma. Our results indicate that the pathogenesis of AD incorporates immune and epidermal barrier defects with combinations of specific and overlapping effects at individual loci.

Journal article

Molyneaux PL, Cox MJ, Mallia P, Johnston SL, Moffatt MF, Cookson WOC, Maher TMet al., 2013, THE ROLE OF THE RESPIRATORY MICROBIOME IN IDIOPATHIC PULMONARY FIBROSIS, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A22-A22, ISSN: 0040-6376

Conference paper

Molyneaux PL, Mallia P, Cox MJ, Footitt J, Willis-Owen SAG, Homola D, Trujillo-Torralbo M-B, Elkin S, Kon OM, Cookson WOC, Moffatt MF, Johnston SLet al., 2013, Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 188, Pages: 1224-1231, ISSN: 1073-449X

Journal article

Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Schwartz DAet al., 2013, Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis., Nat Genet, Vol: 45

Journal article

Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Schwartz DAet al., 2013, Corrigendum: Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis (vol 45, pg 613, 2013), NATURE GENETICS, Vol: 45, Pages: 1409-1409, ISSN: 1061-4036

Journal article

Cox MJ, Cookson WOCM, Moffatt MF, 2013, Sequencing the human microbiome in health and disease, HUMAN MOLECULAR GENETICS, Vol: 22, Pages: R88-R94, ISSN: 0964-6906

Journal article

Cardenas P, Cooper P, Moffatt M, Cookson Wet al., 2013, The development of the upper respiratory microbiome on infancy and the dysbiosis related with wheezing syndrome and health on children from the rural tropics of Ecuador, EUROPEAN RESPIRATORY JOURNAL, Vol: 42, ISSN: 0903-1936

Journal article

Esparza-Gordillo J, Schaarschmidt H, Liang L, Cookson W, Bauerfeind A, Lee-Kirsch M-A, Nemat K, Henderson J, Paternoster L, Harper JI, Mangold E, Nothen MM, Rueschendorf F, Kerscher T, Marenholz I, Matanovic A, Lau S, Keil T, Bauer C-P, Kurek M, Ciechanowicz A, Macek M, Franke A, Kabesch M, Hubner N, Abecasis G, Weidinger S, Moffatt M, Lee Y-Aet al., 2013, A functional IL-6 receptor (<i>IL6R</i>) variant is a risk factor for persistent atopic dermatitis, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 132, Pages: 371-377, ISSN: 0091-6749

Journal article

Binia A, Van Stiphout N, Liang L, Michel S, Bhavsar PK, Chung KF, Brightling CE, Barnes PJ, Kabesch M, Bush A, Cookson WOC, Moffatt MFet al., 2013, A Polymorphism Affecting MYB Binding within the Promoter of the <i>PDCD4</i> Gene is Associated with Severe Asthma in Children, HUMAN MUTATION, Vol: 34, Pages: 1131-1139, ISSN: 1059-7794

Journal article

Cookson WOC, Moffatt MF, 2013, Bedside to Gene and Back in Idiopathic Pulmonary Fibrosis, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 368, Pages: 2228-2230, ISSN: 0028-4793

Journal article

Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Schwartz DAet al., 2013, Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis, Nature Genetics, Vol: 45, Pages: 613-624, ISSN: 1061-4036

We performed a genome-wide association study of non-Hispanic, white individuals with fibrotic idiopathic interstitial pneumonias (IIPs; n = 1,616) and controls (n = 4,683), with follow-up replication analyses in 876 cases and 1,890 controls. We confirmed association with TERT at 5p15, MUC5B at 11p15 and the 3q26 region near TERC, and we identified seven newly associated loci (Pmeta = 2.4 × 10−8 to 1.1 × 10−19), including FAM13A (4q22), DSP (6p24), OBFC1 (10q24), ATP11A (13q34), DPP9 (19p13) and chromosomal regions 7q22 and 15q14-15. Our results suggest that genes involved in host defense, cell-cell adhesion and DNA repair contribute to risk of fibrotic IIPs.

Journal article

Berndt SI, Gustafsson S, Maegi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu Y-J, Lee SH, Liang L, Lin D-Y, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga J-J, Huffman JE, Jarick I, Johansson A, Johnson T, Kanoni S, Kleber ME, Koenig IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Mueller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrieres J, Franke L, Frau F, Gejman PV, Grallert H, Groenberg H, Gudnason V, Hall AS, Hall P, Hartikainen A-L, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hyppoenen E, Iribarren C, Jacobs KB, Jansson J-O, Jula A, Kahonen M, Kathiresan S, Kee F, Khaw K-T, Kivimaki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindstrom J, Liu J, Liuzzi A, Lokki M-L, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, Maerz W, Leach IM, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery GW, Mooser V, Muehleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G, Nohr EA, Ong KK, Oostra BA, Palmer CNA, Palotie A, Peden JF, Pedersen N, Peters A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, Puetter C, Radhakrishnan A, Raitakari O, Rendon A, Rivadeet al., 2013, Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture, NATURE GENETICS, Vol: 45, Pages: 501-U69, ISSN: 1061-4036

Journal article

Duff RM, Simmonds NJ, Davies JC, Wilson R, Alton EW, Pantelidis P, Cox MJ, Cookson WOCM, Bilton D, Moffatt MFet al., 2013, A molecular comparison of microbial communities in bronchiectasis and cystic fibrosis, EUROPEAN RESPIRATORY JOURNAL, Vol: 41, Pages: 991-993, ISSN: 0903-1936

Journal article

Melen E, Granell R, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D, Ege M, Braun-Fahrlaender C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch NM, Curjuric I, Imboden M, Rochat T, Henderson J, Sterne JAC, McArdle WL, Hui J, James AL, Musk AW, Palmer LJ, Becker A, Kozyrskyj AL, Chan-Young M, Park JE, Leung A, Daley D, Freidin MB, Deev IA, Ogorodova LM, Puzyrev VP, Celedon JC, Brehm JM, Cloutier MM, Canino G, Acosta-Perez E, Soto-Quiros M, Avila L, Bergstrom A, Magnusson J, Soderhall C, Kull I, Scholtens S, Boezen HM, Koppelman GH, Wijga AH, Marenholz I, Esparza-Gordillo J, Lau S, Lee Y-A, Standl M, Tiesler CMT, Flexeder C, Heinrich J, Myers RA, Ober C, Nicolae DL, Farrall M, Kumar A, Moffatt MF, Cookson WOCM, Lasky-Su Jet al., 2013, Genome-wide association study of body mass index in 23000 individuals with and without asthma, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 43, Pages: 463-474, ISSN: 0954-7894

Journal article

Liang L, Morar N, Dixon AL, Lathrop GM, Abecasis GR, Moffatt MF, Cookson WOCet al., 2013, A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines, GENOME RESEARCH, Vol: 23, Pages: 716-726, ISSN: 1088-9051

Journal article

Miller S, Obeidat M, Portelli MA, Gowland CJ, Henry AP, Parker SG, Moffatt MF, Wardlaw AJ, Connolly MJ, Hall I, Sayers Iet al., 2013, Snp Rs2070600 Is Associated With Lung Function And The Level Of Serum Soluble Rage In Uk Smokers, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch DA, Groshong SD, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, Du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Schwartz DAet al., 2013, Novel Genetic Risk Loci For Pulmonary Fibrosis, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

van der Harst P, Zhang W, Leach IM, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan S-T, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, Goegele M, Hartiala J, Hersch M, Holm H, Hottenga J-J, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytikainen L-P, Melander O, Murgia F, Nolte IM, O'Reilly PF, Padmanabhan S, Parsa A, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin S-Y, Tang CS, Teumer A, Traglia M, Ulivi S, Westra H-J, Yang J, Zhao JH, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PIW, de Boer RA, de Geus EJC, de Moor MH, Dimitriou M, Domingues FS, Doering A, Engstrom G, Eyjolfsson GI, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Gibson QD, Girotto G, Gudbjartsson DF, Harris SE, Hartikainen A-L, Hastie CE, Hedblad B, Illig T, Jolley J, Kahonen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJF, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Schmidt CO, Sillje HHW, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, van Pelt LJ, van Veldhuisen DJ, Voelker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Algra A, Cucca F, d'Adamo AP, Danesh J, Deary IJ, Dominiczak AF, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin M-R, Khaw KT, Lehtimaki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Smith GD, Smith JG, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Tanget al., 2012, Seventy-five genetic loci influencing the human red blood cell, NATURE, Vol: 492, Pages: 369-+, ISSN: 0028-0836

Journal article

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00457382&limit=30&person=true&page=6&respub-action=search.html