Summary
I work on modelling the HIV epidemic in different settings and amongst different risk populations. My main interest is in interventions which can be used to control or eliminate HIV, both biomedical interventions such as treatment-as-prevention and behavioural interventions such as community mobilization, and factors which can alter their effectiveness.
My current work involves using modelling combined with data from Zimbabwe to understand to what extent different barriers prevent individual from accessing and using HIV prevention tools such as pre-exposure prophylaxis. Previously, I developed a computationally efficient individual-based model of HIV transmission that was used in analysis of results of the HPTN-071 (PopART) trial, a community-based HIV combination prevention trial in Zambia and South Africa. I was also responsible for the impact evaluation of the Avahan India AIDS Initiative established by the Bill & Melinda Gates Foundation, a large-scale targeted HIV intervention promoting condom use and providing STI services as well as structural intervention and community mobilization to around 300,000 highest-risk individuals including female sex workers and men who have sex with men. I have also worked modelling the effect of violence, community empowerment and work environment for female sex workers on increasing their risk of HIV infection.
In my previous job I helped set up the African Institute for Mathematical Sciences in South Africa.
Publications
Journals
Hall M, Golubchik T, Bonsall D, et al., 2024, Demographics of sources of HIV-1 transmission in Zambia: a molecular epidemiology analysis in the HPTN 071 PopART study, The Lancet Microbe, Vol:5, ISSN:2666-5247, Pages:E62-E71
Lazarus L, Herpai N, Pavlova D, et al., 2023, A cross-sectional survey exploring HIV and HCV prevalence among men who purchase sex in Dnipro, Ukraine, Bmc Public Health, Vol:23, ISSN:1471-2458
Davis K, Pickles M, Gregson S, et al., 2023, The effect of universal testing and treatment for HIV on health-related quality of life – an analysis of data from the HPTN 071 (PopART) cluster randomised trial, Ssm: Population Health, Vol:23, ISSN:2352-8273, Pages:1-10
Shaw SY, Leung S, Isac S, et al., 2023, Assessing awareness and use of HIV self-testing kits after the introduction of a community-based HIV self-testing programme among men who have sex with men in Kenya, Plos Global Public Health, Vol:3, ISSN:2767-3375
Bhattacharjee P, Isac S, Musyoki H, et al., 2023, Changes in context, typology and programme outcomes between early and recent periods of sex work among young female sex workers in Mombasa, Kenya: a cross-sectional study, Plos One, Vol:18, ISSN:1932-6203