Imperial College London

ProfessorMichaelPolkey

Faculty of MedicineNational Heart & Lung Institute

Professor of Respiratory Medicine
 
 
 
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Contact

 

+44 (0)20 7351 8029m.polkey

 
 
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Location

 

Respiratory MuscRoyal BromptonRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

655 results found

Stell IM, Polkey MI, Rees PJ, Green M, Moxham Jet al., 2001, Inspiratory muscle strength in acute asthma, CHEST, Vol: 120, Pages: 757-764, ISSN: 0012-3692

Journal article

Lyall RA, Donaldson N, Fleming T, Wood C, Newsom-Davis I, Polkey MI, Leigh PN, Moxham Jet al., 2001, A prospective study of quality of life in ALS patients treated with noninvasive ventilation, NEUROLOGY, Vol: 57, Pages: 153-156, ISSN: 0028-3878

Journal article

Harris ML, Polkey MI, Bath PMW, Moxham Jet al., 2001, Quadriceps muscle weakness following acute hemiplegic stroke, CLINICAL REHABILITATION, Vol: 15, Pages: 274-281, ISSN: 0269-2155

Journal article

Hart N, Sylvester K, Ward S, Cramer D, Moxham J, Polkey MIet al., 2001, Evaluation of an inspiratory muscle trainer in healthy humans, RESPIRATORY MEDICINE, Vol: 95, Pages: 526-531, ISSN: 0954-6111

Journal article

Hughes PD, Hart N, HamnegÄrd CH, Green M, Coats AJS, Moxham J, Polkey MIet al., 2001, Inspiratory muscle relaxation rate slows during exhaustive treadmill walking in patients with chronic heart failure, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 163, Pages: 1400-1403, ISSN: 1073-449X

Journal article

Luo YM, Hart N, Mustfa N, Lyall RA, Polkey MI, Moxham Jet al., 2001, Effect of diaphragm fatigue on neural respiratory drive, JOURNAL OF APPLIED PHYSIOLOGY, Vol: 90, Pages: 1691-1699, ISSN: 8750-7587

Journal article

Chetta A, Harris ML, Lyall RA, Rafferty GF, Polkey MI, Olivieri D, Moxham Jet al., 2001, Whistle mouth pressure as test of expiratory muscle strength, EUROPEAN RESPIRATORY JOURNAL, Vol: 17, Pages: 688-695, ISSN: 0903-1936

Journal article

Rafferty GF, Greenough A, Manczur T, Polkey MI, Harris ML, Heaton ND, Rela M, Moxham Jet al., 2001, Magnetic phrenic nerve stimulation to assess diaphragm function in children following liver transplantation., Pediatr Crit Care Med, Vol: 2, Pages: 122-126, ISSN: 1529-7535

BACKGROUND: An accurate and practical test of diaphragm function in children in the intensive care unit is desirable. Diaphragm dysfunction can occur after liver transplantation and may be a contributory factor in the respiratory complications after the procedure. OBJECTIVE: Our aim was to assess if magnetic stimulation (MS) of the phrenic nerves could be used to assess diaphragm strength in children receiving intensive care. SETTING: Pediatric intensive care unit. PATIENTS: Eight supine, ventilated, sedated children (mean age, 7.3; range, 0.6-15 yrs) were studied within 12 hrs of liver transplantation. INTERVENTIONS: MS was performed using either 90-mm double circular coils or 43-mm figure of eight coils placed over the phrenic nerves on the anterior aspect of the neck. Measurements: The produced diaphragm force was assessed by measuring the transdiaphragmatic pressure (Pdi) with balloons in the mid-esophagus and stomach. During MS, the endotracheal tube was briefly occluded by using a pneumatic valve. MAIN RESULTS: Supramaximal diaphragm force responses were obtained in all subjects; mean Pdi, 7.8 (sd, 3.1) cmH(2)O for left, 5.2 (sd, 3.4) cmH(2)O for right, and 14.8 (sd, 9.2) cmH(2)O for bilateral stimulation. Bland and Altman analysis indicated close agreement between esophageal and airway pressure during MS (mean difference, -0.76 [sd, 0.99] cmH(2)O for left stimulation, 0.81 [sd, 1.25] cmH(2)O for right stimulation, and -0.63 [sd, 1.55] cmH(2)O for bilateral stimulation). In three children, there was a >50% difference between the Pdi generated after left and right unilateral MS and the results of MS indicated complete right hemidiaphragm paralysis in one child. CONCLUSION: MS of the phrenic nerves provides a practical technique for assessing diaphragm function in children receiving intensive care. Measurement of airway pressure during MS may provide a noninvasive technique for assessing diaphragm strength when the use of balloon catheters is contraindicated.

Journal article

Polkey MI, Moxham J, 2001, Clinical aspects of respiratory muscle dysfunction in the critically ill, CHEST, Vol: 119, Pages: 926-939, ISSN: 0012-3692

Journal article

Polkey MI, Roberts PR, 2001, Cardiology and Respiratory Medicine, Editors: JD, London, Publisher: Royal College of Physicians of London and Blackwell Science

Book chapter

Littleton ET, Man WD, Polkey MI, Taylor GPet al., 2001, Human T-cell leukaemia virus type 1-related myopathy causing respiratory failure, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: S65-S65, ISSN: 0889-2229

Journal article

Collier JD, Crown A, Firth JD, Glennon PE, Gurnell M, Roberts PR, Head CEG, Hebden JM, Polkey MI, Shearman J, Qureshi MZ, Walker HA, Ward Net al., 2001, Physiology, Scientific Background to Medicine 1, in Medical Masterclass series, Editors: JD, London, Publisher: Royal College of Physicians and Blackwell Science, Pages: 137-181

Book chapter

Polkey M, 2000, Respiratory care units for non-invasive mechanical ventilation in motor neurone disease - Reply, THORAX, Vol: 55, Pages: 345-346, ISSN: 0040-6376

Journal article

Duguet A, Hart N, Luo YM, Moxham J, Green M, Similowski T, Polkey Met al., 1999, Effect of a maximal isocapnic ventilation on a subsequent maximal isocapnic ventilation., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 159, Pages: A581-A581, ISSN: 1073-449X

Journal article

Harris M, Luo YM, Watson A, Polkey M, Moxham Jet al., 1999, Rapid rate magnetic femoral nerve stimulation to assess quadriceps function, Publisher: AMER THORACIC SOC, Pages: A581-A581, ISSN: 1073-449X

Conference paper

Polkey MI, Lyall RA, Moxham J, Leigh PNet al., 1999, Respiratory aspects of neurological disease, Neurology and medicine, Editors: RAC, Perkin, London, Publisher: BMJ Books

Book chapter

Polkey M, 1996, Amiodarone pneumonitis: No safe dose - Reply, RESPIRATORY MEDICINE, Vol: 90, Pages: 119-119, ISSN: 0954-6111

Journal article

PIOTROWICZ A, POLKEY M, WILKINSON M, 1995, URSODEOXYCHOLIC ACID FOR THE TREATMENT OF FLUCLOXACILLIN-ASSOCIATED CHOLESTASIS, JOURNAL OF HEPATOLOGY, Vol: 22, Pages: 119-120, ISSN: 0169-5185

Journal article

POLKEY M, PATEL J, REES PJ, 1994, PULMONARY-INFILTRATES FOLLOWING BONE-MARROW TRANSPLANTATION, THORAX, Vol: 49, Pages: 624-624, ISSN: 0040-6376

Journal article

POLKEY M, REES PJ, OGG C, 1993, POSSIBLE PERSON-TO-PERSON TRANSMISSION OF ASPERGILLUS, LANCET, Vol: 342, Pages: 435-435, ISSN: 0140-6736

Journal article

POLKEY M, REES J, 1993, POSITIVE PRESSURE BREATHES NEW LIFE INTO NONINVASIVE VENTILATION, BRITISH JOURNAL OF CLINICAL PRACTICE, Vol: 47, Pages: 176-177, ISSN: 0007-0947

Journal article

POLKEY M, 1993, HYPERTENSION GUIDELINES - BEWARE DIURETICS IN ELDERLY PATIENTS, BRITISH MEDICAL JOURNAL, Vol: 306, Pages: 1337-1337, ISSN: 0959-8138

Journal article

Polkey M, Steger A, Elkington S, 1993, Bouveret's syndrome due to four large gall stones., Eur J Med, Vol: 2, Pages: 307-308, ISSN: 1165-0478

Journal article

MARKUS H, POLKEY M, HARRISON M, 1992, VISUAL-LOSS AND OPTIC ATROPHY ASSOCIATED WITH CYPROTERONE-ACETATE, BRITISH MEDICAL JOURNAL, Vol: 305, Pages: 159-159, ISSN: 0959-8138

Journal article

Polkey MI, Moxham J, Pharmacotherapy and hormone therapy of the respiratory muscles in stable COPD, Clinical management of stable COPD, in the series Lung biology in health and disease, Ed. Lenfant C, Editors: Similowski, Whitelaw, Derenne, New York, USA, Publisher: Marcel Dekker

Book chapter

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