Publications
150 results found
Hajji N, Calvert C, Rtichie CW, et al., 2013, The role of metals in Alzheimer’s disease., Editors: Dexter D, Ward R, Crichton R, Dexter, Ward, Crichton, Publisher: The royal society of Chemistry (3 Jun 2013).
Gong B, Pan Y, Vempati P, et al., 2013, Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models, NEUROBIOLOGY OF AGING, Vol: 34, Pages: 1581-1588, ISSN: 0197-4580
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- Citations: 251
Gong B, Pan Y, Vempati P, et al., 2013, Nicotinamide riboside restore cognition through an up-regulation of PGC-1a regulated BACE1 degradation and mitochondrial gene expression in Alzheimer’s mouse models, Neurobiology of Aging
Katsouri L, Vizcaychipi MP, McArthur S, et al., 2013, Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease., Neurobiology of Aging, Vol: 34, Pages: 1105-1115
Parr C, Carzaniga R, Gentleman SM, et al., 2012, Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein, MOLECULAR AND CELLULAR BIOLOGY, Vol: 32, Pages: 4410-4418, ISSN: 0270-7306
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- Citations: 130
Solito E, Sastre M, 2012, Microglia function in Alzheimer's disease, Front Pharmacol., Vol: 3
Katsouri L, Blondrath K, Sastre M, 2012, PPARγ cofactors in neurodegeneration, Iubmb Life
Solito E, Sastre M, 2012, Microglia function in Alzheimer's disease, Frontiers in Pharmacology, Vol: 3
Sastre M, Richardson JC, Gentleman SM, et al., 2011, Inflammatory Risk Factors and Pathologies Associated with Alzheimer's Disease, CURRENT ALZHEIMER RESEARCH, Vol: 8, Pages: 132-141, ISSN: 1567-2050
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- Citations: 51
Thorton C, Bright N, Sastre M, et al., 2011, AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to β-amyloid exposure, Biochemical Journal, Vol: 434, Pages: 503-512
Katsouri L, Parr C, Bogdanovic N, et al., 2011, PPARγ Co-Activator-1α (PGC-1α) Reduces Amyloid-β Generation Through a PPARγ-Dependent Mechanism, JOURNAL OF ALZHEIMERS DISEASE, Vol: 25, Pages: 151-162, ISSN: 1387-2877
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- Citations: 97
Kasouri L, Parr C, Bogdanovic N, et al., 2011, PPARγ co-activator-1α (PGC1 α) reduces Aβ generation through a PPARγ-dependent mechanism, Journal of Alzheimer’s disease, Vol: 25, Pages: 1-12
Sastre M, 2011, Microglia function in Alzheimer's disease, Publisher: Nova Science Publishers, Inc
Thorton C, Bright NJ, Sastre M, et al., 2011, AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure, Biochemical Journal, Vol: 434, Pages: 503-512
Sastre M, 2010, Troubleshooting Methods for APP processing in vitro, J. Pharmacol. Toxicol. Methods., Vol: 61, Pages: 86-91
Sastre M, Gentleman S, 2010, NSAIDs: How they work and their prospects as therapeutics in Alzheimer’s disease., Frontiers in Ageing Neuroscience, Vol: 2
Sastre M, Heneka M, Walter J, et al., 2008, Stimulation with noradrenaline induces a reduction of β-amyloid levels in neuronal cells and in APP/PS1 transgenic mice, FUNDAMENTAL & CLINICAL PHARMACOLOGY, Vol: 22, Pages: 98-98, ISSN: 0767-3981
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- Citations: 1
Sastre M, Walter J, Gentleman SM, 2008, Interactions between APP secretases and inflammatory mediators, JOURNAL OF NEUROINFLAMMATION, Vol: 5, ISSN: 1742-2094
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- Citations: 146
Sastre M, Walter J, 2008, Secretases and inflammation, Recent Advances in the biology of secretases, key proteases in Alzheimer's disease, Publisher: Research Signpost, Pages: 151-166
Mi W, Pawlik M, Sastre M, et al., 2007, Cystatin C inhibits amyloid-β deposition in Alzheimer's disease mouse models, NATURE GENETICS, Vol: 39, Pages: 1440-1442, ISSN: 1061-4036
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- Citations: 152
Lleo A, Galea E, Sastre M, 2007, Molecular targets of non-steroidal anti-inflammatory drugs in neurodegenerative diseases, CELLULAR AND MOLECULAR LIFE SCIENCES, Vol: 64, Pages: 1403-1418, ISSN: 1420-682X
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- Citations: 85
Heneka MT, Sastre M, 2007, Interactions of Neuroinflammatory and Neurodegenerative Mechanisms in Alzheimer's Disease, Glia and inflammation in neurodegenerative disease, Editors: Yenari, Giffard, Pages: 117-157, ISBN: 9781594549847
Braak H, Sastre M, Del Tredici K, 2007, Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease, Acta Neuropatologica
Braak H, Sastre M, Bohl JRE, et al., 2007, Parkinson’s disease: Lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons., Acta Neuropatologica, Vol: 113, Pages: 421-429
Lleo A, Galea E, Sastre M, 2007, Molecular targets of NSAIDs in neurodegenerative diseases., Cel. Molec. Life Sci., Vol: 64, Pages: 1403-1418
Grommes C, Landreth GE, Sastre M, et al., 2006, Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor γ agonist treatment, MOLECULAR PHARMACOLOGY, Vol: 70, Pages: 1524-1533, ISSN: 0026-895X
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- Citations: 78
Sastre M, Klockgether T, Heneka MT, 2006, Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms, INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, Vol: 24, Pages: 167-176, ISSN: 0736-5748
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- Citations: 341
Heneka MT, Ramanathan M, Jacobs AH, et al., 2006, Locus Ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice, JOURNAL OF NEUROSCIENCE, Vol: 26, Pages: 1343-1354, ISSN: 0270-6474
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- Citations: 242
Sastre M, Dewachter I, Rossner S, et al., 2006, Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 103, Pages: 443-448, ISSN: 0027-8424
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- Citations: 338
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