Imperial College London

ProfessorMiguelSeabra

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
//

Contact

 

+44 (0)20 7594 3024m.seabra Website

 
 
//

Assistant

 

Mr Peter Moore +44 (0)20 7594 3175

 
//

Location

 

Office 259Sir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Summary

Professor Seabra´s research interests include fundamental Cell and Molecular Biology topics such as protein prenylation, membrane identity and traffic, function of Rab GTPases in organelle biogenesis, motility, secretion and phagocytosis. He is also interested in the cellular and molecular basis of diseases and is currently involved in research on retinal degenerations (Choroideremia and AMD), pigmentation  dysfunction syndromes (Griscelli Syndromes), and host-pathogen interactions (Malaria).

 

Publications

Journals

Alexander M, Ramstead AG, Bauer KM, et al., 2017, Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli, Journal of Immunology, Vol:199, ISSN:0022-1767, Pages:3559-3570

Correia MS, Moreiras H, Pereira FJC, et al., 2017, Melanin transferred to keratinocytes resides in non-degradative endocytic compartments., J Invest Dermatol

Edwards TL, Jolly JK, Groppe M, et al., 2016, Visual Acuity after Retinal Gene Therapy for Choroideremia, New England Journal of Medicine, Vol:374, ISSN:0028-4793, Pages:1996-1998

Wankel B, Ouyang J, Guo X, et al., 2016, Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells, Molecular Biology of the Cell, Vol:27, ISSN:1059-1524, Pages:1621-1634

Thieleke-Matos C, da Silva ML, Cabrita-Santos L, et al., 2016, Host cell autophagy contributes to Plasmodium liver development, Cellular Microbiology, Vol:18, ISSN:1462-5814, Pages:437-450

More Publications