Imperial College London

ProfessorMiguelSeabra

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 3024m.seabra Website

 
 
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Assistant

 

Mr Peter Moore +44 (0)20 7594 3175

 
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Location

 

Office 259Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

Professor Seabra´s research interests include fundamental Cell and Molecular Biology topics such as protein prenylation, membrane identity and traffic, function of Rab GTPases in organelle biogenesis, motility, secretion and phagocytosis. He is also interested in the cellular and molecular basis of diseases and is currently involved in research on retinal degenerations (Choroideremia and AMD), pigmentation  dysfunction syndromes (Griscelli Syndromes), and host-pathogen interactions (Malaria).

 

Publications

Journals

Alexander M, Ramstead AG, Bauer KM, et al., 2017, Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli., J Immunol

Booth AEG, Tarafder AK, Hume AN, et al., 2016, A Role for Na+,K+-ATPase alpha 1 in Regulating Rab27a Localisation on Melanosomes (vol 9, e102851, 2014), Plos One, Vol:11, ISSN:1932-6203

Edwards TL, Jolly JK, Groppe M, et al., 2016, Visual Acuity after Retinal Gene Therapy for Choroideremia, New England Journal of Medicine, Vol:374, ISSN:0028-4793, Pages:1996-1998

Thieleke-Matos C, da Silva ML, Cabrita-Santos L, et al., 2016, Host cell autophagy contributes to Plasmodium liver development, Cellular Microbiology, Vol:18, ISSN:1462-5814, Pages:437-450

Conference

Seabra MC, Barral DC, Correia MS, et al., 2016, Mechanisms of melanin transfer from melanocytes and formation of a parasol in keratinocytes, Annual Meeting of the American-Society-for-Cell-Biology (ASCB), AMER SOC CELL BIOLOGY, ISSN:1059-1524

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