Professor Seabra´s research interests include fundamental Cell and Molecular Biology topics such as protein prenylation, membrane identity and traffic, function of Rab GTPases in organelle biogenesis, motility, secretion and phagocytosis. He is also interested in the cellular and molecular basis of diseases and is currently involved in research on retinal degenerations (Choroideremia and AMD), pigmentation dysfunction syndromes (Griscelli Syndromes), and host-pathogen interactions (Malaria).
et al., 2016, Correction: A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes., Plos One, Vol:11
et al., 2016, Visual Acuity after Retinal Gene Therapy for Choroideremia, New England Journal of Medicine, Vol:374, ISSN:0028-4793, Pages:1996-1998
et al., 2016, Host cell autophagy contributes to Plasmodium liver development, Cellular Microbiology, Vol:18, ISSN:1462-5814, Pages:437-450
et al., 2016, Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells, Molecular Biology of the Cell, Vol:27, ISSN:1059-1524, Pages:1621-1634
et al., 2016, Mechanisms of melanin transfer from melanocytes and formation of a parasol in keratinocytes, Annual Meeting of the American-Society-for-Cell-Biology (ASCB), AMER SOC CELL BIOLOGY, ISSN:1059-1524