Professor Seabra´s research interests include fundamental Cell and Molecular Biology topics such as protein prenylation, membrane identity and traffic, function of Rab GTPases in organelle biogenesis, motility, secretion and phagocytosis. He is also interested in the cellular and molecular basis of diseases and is currently involved in research on retinal degenerations (Choroideremia and AMD), pigmentation dysfunction syndromes (Griscelli Syndromes), and host-pathogen interactions (Malaria).
et al., 2017, Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli, Journal of Immunology, Vol:199, ISSN:0022-1767, Pages:3559-3570
et al., 2017, Melanin transferred to keratinocytes resides in non-degradative endocytic compartments., J Invest Dermatol
et al., 2016, Visual Acuity after Retinal Gene Therapy for Choroideremia, New England Journal of Medicine, Vol:374, ISSN:0028-4793, Pages:1996-1998
et al., 2016, Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells, Molecular Biology of the Cell, Vol:27, ISSN:1059-1524, Pages:1621-1634
et al., 2016, Host cell autophagy contributes to Plasmodium liver development, Cellular Microbiology, Vol:18, ISSN:1462-5814, Pages:437-450