Professor Seabra´s research interests include fundamental Cell and Molecular Biology topics such as protein prenylation, membrane identity and traffic, function of Rab GTPases in organelle biogenesis, motility, secretion and phagocytosis. He is also interested in the cellular and molecular basis of diseases and is currently involved in research on retinal degenerations (Choroideremia and AMD), pigmentation dysfunction syndromes (Griscelli Syndromes), and host-pathogen interactions (Malaria).
et al., 2017, Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli., J Immunol
et al., 2016, A Role for Na+,K+-ATPase alpha 1 in Regulating Rab27a Localisation on Melanosomes (vol 9, e102851, 2014), Plos One, Vol:11, ISSN:1932-6203
et al., 2016, Visual Acuity after Retinal Gene Therapy for Choroideremia, New England Journal of Medicine, Vol:374, ISSN:0028-4793, Pages:1996-1998
et al., 2016, Host cell autophagy contributes to Plasmodium liver development, Cellular Microbiology, Vol:18, ISSN:1462-5814, Pages:437-450
et al., 2016, Mechanisms of melanin transfer from melanocytes and formation of a parasol in keratinocytes, Annual Meeting of the American-Society-for-Cell-Biology (ASCB), AMER SOC CELL BIOLOGY, ISSN:1059-1524