Murray Selkirk earned his PhD at the National Institute for Medical Research, Mill Hill, where he studied immunosuppression in murine trypanosomiasis with Bridget Ogilvie. He then joined the University of Washington, Seattle, working with Nina Agabian on antigenic variation in trypanosomes, and after a brief spell at the Naval Biosciences Laboratory in Oakland, joined Rick Maizels at Imperial College, switching his attention to nematode parasites, in particular those responsible for lymphatic filariasis. He was appointed to a Lectureship in the Department of Biochemistry in 1986, and is currently Professor of Biochemical Parasitology and Head of the Department of Life Sciences. His research group works on nematode parasites, aiming primarily to understand how these pathogens effect long-term survival in mammalian hosts, with a particular focus on molecular mechanisms underlying regulation of the host immune system and resistance to immunity.
et al., 2016, The genome of Strongyloides spp. gives insights into protein families with a putative role in nematode parasitism., Parasitology, Pages:1-16
et al., 2016, The Helminth-Derived Immunomodulator AvCystatin Reduces Virus Enhanced Inflammation by Induction of Regulatory IL-10(+) T Cells, Plos One, Vol:11, ISSN:1932-6203
et al., 2016, Surfactant Protein-D Is Essential for Immunity to Helminth Infection, Plos Pathogens, Vol:12, ISSN:1553-7366
et al., 2016, Modulation of the Immune Response by Nematode Secreted Acetylcholinesterase Revealed by Heterologous Expression in Trypanosoma musculi, Plos Pathogens, Vol:12, ISSN:1553-7366
et al., 2016, Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis, Plos Pathogens, Vol:12, ISSN:1553-7366