Imperial College London

ProfessorMurraySelkirk

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biochemical Parasitology
 
 
 
//

Contact

 

+44 (0)20 7594 5214m.selkirk Website

 
 
//

Location

 

204Sir Ernst Chain BuildingSouth Kensington Campus

//

Summary

 

Summary

Murray Selkirk earned his PhD at the National Institute for Medical Research, Mill Hill, where he studied immunosuppression in murine trypanosomiasis with Bridget Ogilvie. He then joined the University of Washington, Seattle, working with Nina Agabian on antigenic variation in trypanosomes, and after a brief spell at the Naval Biosciences Laboratory in Oakland, joined Rick Maizels at Imperial College, switching his attention to nematode parasites, in particular those responsible for lymphatic filariasis. He was appointed to a Lectureship in the Department of Biochemistry in 1986, and is currently Professor of Biochemical Parasitology. His research group works on nematode parasites, aiming primarily to understand how these pathogens effect long-term survival in mammalian hosts, with a particular focus on molecular mechanisms underlying regulation of the host immune system and resistance to immunity.  

 

 

Publications

Journals

Selkirk ME, Davis RE, Gounaris K, et al., 2018, Special issue: molecular and cellular biology of helminth parasites XI Preface, International Journal for Parasitology, Vol:48, ISSN:0020-7519, Pages:319-320

Rosic S, Amouroux R, Requena CE, et al., 2018, Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity, Nature Genetics, Vol:50, ISSN:1061-4036

Chatonnet A, Lenfant N, Marchot P, et al., 2017, Natural genomic amplification of cholinesterase genes in animals, Journal of Neurochemistry, Vol:142, ISSN:0022-3042, Pages:73-81

Hunt VL, Tsai IJ, Selkirk ME, et al., 2017, The genome of Strongyloides spp. gives insights into protein families with a putative role in nematode parasitism, Parasitology, Vol:144, ISSN:0031-1820, Pages:343-358

Schuijs MJ, Hartmann S, Selkirk ME, et al., 2016, The Helminth-Derived Immunomodulator AvCystatin Reduces Virus Enhanced Inflammation by Induction of Regulatory IL-10(+) T Cells, Plos One, Vol:11, ISSN:1932-6203

More Publications