Publications
332 results found
Harrison PM, Sternberg MJE, 1996, The disulphide beta-cross: From cystine geometry and clustering to classification of small disulphide-rich protein folds, JOURNAL OF MOLECULAR BIOLOGY, Vol: 264, Pages: 603-623, ISSN: 0022-2836
- Author Web Link
- Cite
- Citations: 110
King RD, Sternberg MJE, 1996, Identification and application of the concepts important for accurate and reliable protein secondary structure prediction, PROTEIN SCIENCE, Vol: 5, Pages: 2298-2310, ISSN: 0961-8368
- Author Web Link
- Cite
- Citations: 342
Srinivasan A, Muggleton SH, Sternberg MJE, et al., 1996, Theories for mutagenicity: A study in first-order and feature-based induction, ARTIFICIAL INTELLIGENCE, Vol: 85, Pages: 277-299, ISSN: 0004-3702
- Author Web Link
- Cite
- Citations: 125
Brutlag DL, Sternberg MJE, 1996, Sequences and topology - Challenges for algorithms and experts - Editorial overview, CURRENT OPINION IN STRUCTURAL BIOLOGY, Vol: 6, Pages: 343-345, ISSN: 0959-440X
Brutlag DL, Sternberg MJ, 1996, Sequences and topology challenges for algorithms and experts., Curr Opin Struct Biol, Vol: 6, Pages: 343-345, ISSN: 0959-440X
King RD, Srinivasan A, Sternberg MJE, 1996, Relating chemical activity to structure: An examination of ILP successes, New Generation Computing, Vol: 14, ISSN: 0288-3635
Strynadka NCJ, Eisenstein M, KatchalskiKatzir E, et al., 1996, Molecular docking programs successfully predict the binding of a beta-lactamase inhibitory protein to TEM-1 beta-lactamase, NATURE STRUCTURAL BIOLOGY, Vol: 3, Pages: 233-239, ISSN: 1072-8368
- Author Web Link
- Cite
- Citations: 117
Russell RB, Sternberg MJE, 1996, A novel binding site in catalase is suggested by structural similarity to the calycin superfamily, PROTEIN ENGINEERING, Vol: 9, Pages: 107-111, ISSN: 0269-2139
- Author Web Link
- Cite
- Citations: 7
King RD, Muggleton SH, Srinivasan A, et al., 1996, Structure-activity relationships derived by machine learning: The use of atoms and their bond connectivities to predict mutagenicity by inductive logic programming, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 93, Pages: 438-442, ISSN: 0027-8424
- Author Web Link
- Cite
- Citations: 155
King RD, Srinivasan A, Sternberg MJE, 1996, Relating chemical activity to structure: An examination of ILP successes (vol 13, pg 411, 1995), NEW GENERATION COMPUTING, Vol: 14, Pages: 109-109, ISSN: 0288-3635
Bates PA, Jackson RM, Sternberg MJE, 1996, Prediction of protein structures and their docking, 7th SmithKline-Beecham International Symposium on Genomes, Molecular Biology and Drug Discovery, Publisher: ACADEMIC PRESS LTD, Pages: 73-86
- Author Web Link
- Cite
- Citations: 5
Sternberg MJE, 1996, Protein Structure Prediction - A Practical Approach, Oxford, Publisher: Oxford University Press
ELLIS SW, HAYHURST GP, SMITH G, et al., 1995, EVIDENCE THAT ASPARTIC-ACID-301 IS A CRITICAL SUBSTRATE-CONTACT RESIDUE IN THE ACTIVE-SITE OF CYTOCHROME-P450 2D6, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 270, Pages: 29055-29058, ISSN: 0021-9258
- Author Web Link
- Cite
- Citations: 113
DOIG AJ, STERNBERG MJE, 1995, SIDE-CHAIN CONFORMATIONAL ENTROPY IN PROTEIN-FOLDING, PROTEIN SCIENCE, Vol: 4, Pages: 2247-2251, ISSN: 0961-8368
- Author Web Link
- Cite
- Citations: 243
CHICKOS JS, STERNBERG MJE, 1995, A TEST OF THE APPLICABILITY OF SMALL-MOLECULE GROUP ADDITIVITY PARAMETERS IN THE ESTIMATION OF FUSION ENTROPIES OF MACROMOLECULES, THERMOCHIMICA ACTA, Vol: 264, Pages: 13-26, ISSN: 0040-6031
- Author Web Link
- Cite
- Citations: 1
JACKSON RM, STERNBERG MJE, 1995, A CONTINUUM MODEL FOR PROTEIN-PROTEIN INTERACTIONS - APPLICATION TO THE DOCKING PROBLEM, JOURNAL OF MOLECULAR BIOLOGY, Vol: 250, Pages: 258-275, ISSN: 0022-2836
- Author Web Link
- Cite
- Citations: 139
ISLAM SA, LUO JC, STERNBERG MJE, 1995, IDENTIFICATION AND ANALYSIS OF DOMAINS IN PROTEINS, PROTEIN ENGINEERING, Vol: 8, Pages: 513-525, ISSN: 0269-2139
- Author Web Link
- Cite
- Citations: 100
RUSSELL RB, STERNBERG MJE, 1995, STRUCTURE PREDICTION - HOW GOOD ARE WE, CURRENT BIOLOGY, Vol: 5, Pages: 488-490, ISSN: 0960-9822
- Author Web Link
- Cite
- Citations: 18
STERNBERG MJE, MUGGLETON S, SHRINIVASAN A, 1995, DRUG DESIGN BY MACHINE LEARNING, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 209, Pages: 165-COMP, ISSN: 0065-7727
- Author Web Link
- Cite
- Citations: 1
KING RD, HIRST JD, STERNBERG MJE, 1995, COMPARISON OF ARTIFICIAL-INTELLIGENCE METHODS FOR MODELING PHARMACEUTICAL QSARS, APPLIED ARTIFICIAL INTELLIGENCE, Vol: 9, Pages: 213-233, ISSN: 0883-9514
- Author Web Link
- Cite
- Citations: 13
KING RD, STERNBERG MJE, SRINIVASAN A, 1995, RELATING CHEMICAL ACTIVITY TO STRUCTURE - AN EXAMINATION OF ILP SUCCESSES, NEW GENERATION COMPUTING, Vol: 13, Pages: 411-433, ISSN: 0288-3635
- Author Web Link
- Cite
- Citations: 44
Sternberg MJ, Hegyi H, Islam SA, et al., 1995, Towards an intelligent system for the automatic assignment of domains in globular proteins., Proc Int Conf Intell Syst Mol Biol, Vol: 3, Pages: 376-383, ISSN: 1553-0833
The automatic identification of protein domains from coordinates is the first step in the classification of protein folds and hence is required for databases to guide structure prediction. Most algorithms encode a single concept based and sometimes do not yield assignments that are consistent with the generally accepted perception. Our development of an automatic approach to identify reliably domains from protein coordinates is described. The algorithm is benchmarked against a manual identification of the domains in 284 representative protein chains. The first step is the domain assignment by distance (DAD) algorithm that considers the density of inter-residue contacts represented in a contact matrix. The algorithm yields 85% agreement with the manual assignment. The paper then considers how the reliability of these assignments could be evaluated. Finally the use of structural comparisons using the STAMP algorithm to validate domain assignment is reported on a test case.
HARRISON PM, STERNBERG MJE, 1994, ANALYSIS AND CLASSIFICATION OF DISULFIDE CONNECTIVITY IN PROTEINS - THE ENTROPIC EFFECT OF CROSS-LINKAGE, JOURNAL OF MOLECULAR BIOLOGY, Vol: 244, Pages: 448-463, ISSN: 0022-2836
- Author Web Link
- Cite
- Citations: 59
ADZHUBEI AA, STERNBERG MJE, 1994, CONSERVATION OF POLYPROLINE-II HELICES IN HOMOLOGOUS PROTEINS - IMPLICATIONS FOR STRUCTURE PREDICTION BY MODEL-BUILDING, PROTEIN SCIENCE, Vol: 3, Pages: 2395-2410, ISSN: 0961-8368
- Author Web Link
- Cite
- Citations: 45
KING RD, CLARK DA, SHIRAZI J, et al., 1994, ON THE USE OF MACHINE LEARNING TO IDENTIFY TOPOLOGICAL RULES IN THE PACKING OF BETA-STRANDS, PROTEIN ENGINEERING, Vol: 7, Pages: 1295-1303, ISSN: 0269-2139
- Author Web Link
- Cite
- Citations: 13
STERNBERG MJE, MUGGLETON S, SHRINIVASAN A, 1994, DRUG DESIGN BY MACHINE LEARNING, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 208, Pages: 138-COMP, ISSN: 0065-7727
HIRST JD, KING RD, STERNBERG MJE, 1994, QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS BY NEURAL NETWORKS AND INDUCTIVE LOGIC PROGRAMMING .1. THE INHIBITION OF DIHYDROFOLATE-REDUCTASE BY PYRIMIDINES, JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, Vol: 8, Pages: 405-420, ISSN: 0920-654X
- Author Web Link
- Cite
- Citations: 68
HIRST JD, KING RD, STERNBERG MJE, 1994, QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS BY NEURAL NETWORKS AND INDUCTIVE LOGIC PROGRAMMING .2. THE INHIBITION OF DIHYDROFOLATE-REDUCTASE BY TRIAZINES, JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, Vol: 8, Pages: 421-432, ISSN: 0920-654X
- Author Web Link
- Cite
- Citations: 42
STERNBERG MJE, KING RD, LEWIS RA, et al., 1994, APPLICATION OF MACHINE LEARNING TO STRUCTURAL MOLECULAR-BIOLOGY, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, Vol: 344, Pages: 365-371, ISSN: 0962-8436
- Author Web Link
- Cite
- Citations: 25
JACKSON RM, STERNBERG MJE, 1994, APPLICATION OF SCALED PARTICLE THEORY TO MODEL THE HYDROPHOBIC EFFECT - IMPLICATIONS FOR MOLECULAR ASSOCIATION AND PROTEIN STABILITY, PROTEIN ENGINEERING, Vol: 7, Pages: 371-383, ISSN: 0269-2139
- Author Web Link
- Cite
- Citations: 84
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.