Imperial College London

Professor Molly Stevens FREng

Faculty of EngineeringDepartment of Materials

Prof of Biomedical Materials&Regenerative Medicine



+44 (0)20 7594 6804m.stevens




208Royal School of MinesSouth Kensington Campus






BibTex format

author = {Lin, Y and Charchar, P and Christofferson, AJ and Thomas, MR and Todorova, N and Mazo, MM and Chen, Q and Doutch, J and Richardson, R and Yarovsky, I and Stevens, M},
doi = {10.1021/jacs.8b04436},
journal = {Journal of the American Chemical Society},
pages = {18217--18226},
title = {Surface dynamics and ligand-core interactions of quantum sized photoluminescent gold nanoclusters},
url = {},
volume = {140},
year = {2018}

RIS format (EndNote, RefMan)

AB - Quantum-sized metallic clusters protected by biological ligands represent a new class of luminescent materials; yet the understanding of structural information and photoluminescence origin of these ultrasmall clusters remains a challenge. Herein we systematically study the surface ligand dynamics and ligand–metal core interactions of peptide-protected gold nanoclusters (AuNCs) with combined experimental characterizations and theoretical molecular simulations. We show that the peptide sequence plays an important role in determining the surface peptide structuring, interfacial water dynamics and ligand–Au core interaction, which can be tailored by controlling peptide acetylation, constituent amino acid electron donating/withdrawing capacity, aromaticity/hydrophobicity and by adjusting environmental pH. Specifically, emission enhancement is achieved through increasing the electron density of surface ligands in proximity to the Au core, discouraging photoinduced quenching, and by reducing the amount of surface-bound water molecules. These findings provide key design principles for understanding the surface dynamics of peptide-protected nanoparticles and maximizing the photoluminescence of metallic clusters through the exploitation of biologically relevant ligand properties.
AU - Lin,Y
AU - Charchar,P
AU - Christofferson,AJ
AU - Thomas,MR
AU - Todorova,N
AU - Mazo,MM
AU - Chen,Q
AU - Doutch,J
AU - Richardson,R
AU - Yarovsky,I
AU - Stevens,M
DO - 10.1021/jacs.8b04436
EP - 18226
PY - 2018///
SN - 1520-5126
SP - 18217
TI - Surface dynamics and ligand-core interactions of quantum sized photoluminescent gold nanoclusters
T2 - Journal of the American Chemical Society
UR -
UR -
VL - 140
ER -