Imperial College London

Professor Molly Stevens FREng

Faculty of EngineeringDepartment of Materials

Prof of Biomedical Materials&Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Chandrawati:2017:10.1002/adma.201604932,
author = {Chandrawati, R and Chang, J and Reina-Torres, E and Jumeaux, C and Sherwood, JM and Stamer, WD and Zelikin, AN and Overby, DR and Stevens, MM},
doi = {10.1002/adma.201604932},
journal = {Advanced Materials},
title = {Localized and controlled delivery of nitric oxide to the conventional outflow pathway via enzyme biocatalysis: towards therapy for Glaucoma},
url = {http://dx.doi.org/10.1002/adma.201604932},
volume = {29},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Nitric oxide (NO) has been shown to lower intraocular pressure (IOP), however its therapeutic effects on outflow physiology are location- and dose-dependent. Here, a NO delivery platform that directly targets the resistance-generating region of the conventional outflow pathway and locally liberates a controlled dose of NO is reported. An increase in outflow facility (decrease in IOP) is demonstrated in mouse model.
AU - Chandrawati,R
AU - Chang,J
AU - Reina-Torres,E
AU - Jumeaux,C
AU - Sherwood,JM
AU - Stamer,WD
AU - Zelikin,AN
AU - Overby,DR
AU - Stevens,MM
DO - 10.1002/adma.201604932
PY - 2017///
SN - 1521-4095
TI - Localized and controlled delivery of nitric oxide to the conventional outflow pathway via enzyme biocatalysis: towards therapy for Glaucoma
T2 - Advanced Materials
UR - http://dx.doi.org/10.1002/adma.201604932
UR - http://hdl.handle.net/10044/1/43593
VL - 29
ER -