Imperial College London

Professor Molly Stevens FREng

Faculty of EngineeringDepartment of Materials

Prof of Biomedical Materials&Regenerative Medicine
 
 
 
//

Contact

 

+44 (0)20 7594 6804m.stevens

 
 
//

Location

 

208Royal School of MinesSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Chung:2017:10.1002/marc.201700168,
author = {Chung, JJ and Sum, BST and Li, S and Stevens, MM and Georgiou, TK and Jones, JR},
doi = {10.1002/marc.201700168},
journal = {Macromolecular Rapid Communications},
title = {Effect of comonomers on physical properties and cell attachment to silica-methacrylate/acrylate hybrids for bone substitution},
url = {http://dx.doi.org/10.1002/marc.201700168},
volume = {38},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Hybrids with a silica network covalently bonded to a polymer are promising materials for bone repair. Previous work on synthesizing methyl methacrylate (MMA) based copolymers by reversible additionfragmentation chain transfer (RAFT) polymerization gives high tailorability of mechanical properties since sophisticated polymer structures can be designed. However, more flexible hybrids would be beneficial. Here, nbutyl methacrylate (BMA) and methyl acrylate (MA) based hybrids are produced. Unlike MMA, BMA and MA hybrids do not show plastic deformation, and BMA hybrid has strain to failure of 33%. Although the new hybrids are more flexible, preosteoblast cells do not adhere on their surfaces, due to higher hydrophobicity and lower stiffness. Comonomer choice is crucial for bone regenerative hybrids.
AU - Chung,JJ
AU - Sum,BST
AU - Li,S
AU - Stevens,MM
AU - Georgiou,TK
AU - Jones,JR
DO - 10.1002/marc.201700168
PY - 2017///
SN - 1022-1336
TI - Effect of comonomers on physical properties and cell attachment to silica-methacrylate/acrylate hybrids for bone substitution
T2 - Macromolecular Rapid Communications
UR - http://dx.doi.org/10.1002/marc.201700168
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406833600005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/62748
VL - 38
ER -