Imperial College London

Professor Molly Stevens FREng

Faculty of EngineeringDepartment of Materials

Prof of Biomedical Materials&Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ember:2017:10.1038/s41536-017-0014-3,
author = {Ember, KJI and Hoeve, MA and McAughtrie, SL and Bergholt, MS and Dwyer, BJ and Stevens, MM and Faulds, K and Forbes, SJ and Campbell, CJ},
doi = {10.1038/s41536-017-0014-3},
journal = {npj Regenerative Medicine},
title = {Raman spectroscopy and regenerative medicine: a review},
url = {http://dx.doi.org/10.1038/s41536-017-0014-3},
volume = {2},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The field of regenerative medicine spans a wide area of the biomedical landscape—from single cell culture in laboratories to human whole-organ transplantation. To ensure that research is transferrable from bench to bedside, it is critical that we are able to assess regenerative processes in cells, tissues, organs and patients at a biochemical level. Regeneration relies on a large number of biological factors, which can be perturbed using conventional bioanalytical techniques. A versatile, non-invasive, non-destructive technique for biochemical analysis would be invaluable for the study of regeneration; and Raman spectroscopy is a potential solution. Raman spectroscopy is an analytical method by which chemical data are obtained through the inelastic scattering of light. Since its discovery in the 1920s, physicists and chemists have used Raman scattering to investigate the chemical composition of a vast range of both liquid and solid materials. However, only in the last two decades has this form of spectroscopy been employed in biomedical research. Particularly relevant to regenerative medicine are recent studies illustrating its ability to characterise and discriminate between healthy and disease states in cells, tissue biopsies and in patients. This review will briefly outline the principles behind Raman spectroscopy and its variants, describe key examples of its applications to biomedicine, and consider areas of regenerative medicine that would benefit from this non-invasive bioanalytical tool.
AU - Ember,KJI
AU - Hoeve,MA
AU - McAughtrie,SL
AU - Bergholt,MS
AU - Dwyer,BJ
AU - Stevens,MM
AU - Faulds,K
AU - Forbes,SJ
AU - Campbell,CJ
DO - 10.1038/s41536-017-0014-3
PY - 2017///
SN - 2057-3995
TI - Raman spectroscopy and regenerative medicine: a review
T2 - npj Regenerative Medicine
UR - http://dx.doi.org/10.1038/s41536-017-0014-3
UR - http://hdl.handle.net/10044/1/54545
VL - 2
ER -