Imperial College London

Professor Molly Stevens

Faculty of EngineeringDepartment of Materials

Professor of Biomedical Materials and Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

495 results found

Aili D, Gryko P, Sepulveda B, Dick JAG, Kirby N, Heenan R, Baltzer L, Liedberg B, Ryan MP, Stevens MMet al., 2011, Polypeptide Folding-Mediated Tuning of the Optical and Structural Properties of Gold Nanoparticle Assemblies, NANO LETTERS, Vol: 11, Pages: 5564-5573, ISSN: 1530-6984

Journal article

Ball MD, Bonzani IC, Bovis MJ, Williams A, Stevens MMet al., 2011, Human Periosteum Is a Source of Cells for Orthopaedic Tissue Engineering: A Pilot Study, CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, Vol: 469, Pages: 3085-3093, ISSN: 0009-921X

Journal article

Place ES, Rojo L, Gentleman E, Sardinha JP, Stevens MMet al., 2011, Strontium- and Zinc-Alginate Hydrogels for Bone Tissue Engineering, TISSUE ENGINEERING PART A, Vol: 17, Pages: 2713-2722, ISSN: 1937-3341

Journal article

McCullen SD, Chow AGY, Stevens MM, 2011, <i>In vivo</i> tissue engineering of musculoskeletal tissues, CURRENT OPINION IN BIOTECHNOLOGY, Vol: 22, Pages: 715-720, ISSN: 0958-1669

Journal article

Mager MD, LaPointe V, Stevens MM, 2011, Exploring and exploiting chemistry at the cell surface, NATURE CHEMISTRY, Vol: 3, Pages: 582-589, ISSN: 1755-4330

Journal article

Brauer DS, Gentleman E, Farrar DF, Stevens MM, Hill RGet al., 2011, Benefits and drawbacks of zinc in glass ionomer bone cements, BIOMEDICAL MATERIALS, Vol: 6, ISSN: 1748-6041

Journal article

Bertazzo S, Cloyd KL, Gentleman E, El-Hamamsy I, Chester AH, Yacoub MH, Stevens MMet al., 2011, NANO- AND MICRO-STRUCTURE OF CALCIFICATION IN HUMAN AORTIC VALVE, AORTA AND CORONARY WALL, 79th Congress of the European-Atherosclerosis-Society (EAS), Publisher: ELSEVIER IRELAND LTD, Pages: 62-62, ISSN: 1567-5688

Conference paper

Lim EH, Sardinha JP, Shefelbine S, Myers SR, Stevens MMet al., 2011, State-of-the-Art Smart Biomimetic Scaffold for Cartilage Regeneration: <i>In</i>-<i>vitro</i> and <i>In</i>-<i>vivo</i> Studies, Annual Meeting of the Society-of-Academic-and-Research-Surgeons, Publisher: WILEY-BLACKWELL, Pages: E11-E11, ISSN: 0007-1323

Conference paper

Aili D, Mager M, Roche D, Stevens MMet al., 2011, Hybrid Nanoparticle-Liposome Detection of Phospholipase Activity, NANO LETTERS, Vol: 11, Pages: 1401-1405, ISSN: 1530-6984

Journal article

Hung A, Mwenifumbo S, Mager M, Kuna JJ, Stellacci F, Yarovsky I, Stevens MMet al., 2011, Ordering Surfaces on the Nanoscale: Implications for Protein Adsorption, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 133, Pages: 1438-1450, ISSN: 0002-7863

Journal article

Stevens MM, 2011, Exploring and Engineering the Cell-Surface Interface, 55th Annual Meeting of the Biophysical-Society, Publisher: CELL PRESS, Pages: 189-189, ISSN: 0006-3495

Conference paper

Labbaf S, Tsigkou O, Mueller KH, Stevens MM, Porter AE, Jones JRet al., 2011, Spherical bioactive glass particles and their interaction with human mesenchymal stem cells <i>in vitro</i>, BIOMATERIALS, Vol: 32, Pages: 1010-1018, ISSN: 0142-9612

Journal article

Vanleene M, Saldanha Z, Cloyd KL, Jell G, Bou-Gharios G, Bassett JH, Williams GR, Fisk NM, Oyen ML, Stevens MM, Shefelbine SJ, Guillot PVet al., 2011, Transplantation of human fetal blood stem cells in the osteogenesis imperfecta mouse leads to improvement in multiscale tissue properties., Blood, Vol: 117, Pages: 1053-1060

Osteogenesis imperfecta (OI or brittle bone disease) is a disorder of connective tissues caused by mutations in the collagen genes. We previously showed that intrauterine transplantation of human blood fetal stem/stromal cells in OI mice (oim) resulted in a significant reduction of bone fracture. This work examines the cellular mechanisms and mechanical bone modifications underlying these therapeutic effects, particularly examining the direct effects of donor collagen expression on bone material properties. In this study, we found an 84% reduction in femoral fractures in transplanted oim mice. Fetal blood stem/stromal cells engrafted in bones, differentiated into mature osteoblasts, expressed osteocalcin, and produced COL1a2 protein, which is absent in oim mice. The presence of normal collagen decreased hydroxyproline content in bones, altered the apatite crystal structure, increased the bone matrix stiffness, and reduced bone brittleness. In conclusion, expression of normal collagen from mature osteoblast of donor origin significantly decreased bone brittleness by improving the mechanical integrity of the bone at the molecular, tissue, and whole bone levels.

Journal article

Clarke DE, McCullen SD, Chow AGY, Stevens MMet al., 2011, Functional Biomaterials, COMPREHENSIVE BIOTECHNOLOGY, VOL 5: MEDICAL BIOTECHNOLOGY AND HEALTHCARE, 2ND EDITION, Editors: MooYoung, Publisher: ELSEVIER SCIENCE BV, Pages: 3-10

Book chapter

Basey-Fisher TH, Hanham SM, Andresen H, Maier SA, Stevens MM, Alford NM, Klein Net al., 2011, Microwave Debye relaxation analysis of dissolved proteins: Towards free-solution biosensing, Applied Physics Letters, Vol: 99, Pages: 233703-233703

Journal article

Woodward RT, Hight C, Yildiz U, Schaeffer N, Valliant EM, Jones JR, Stevens MM, Weaver JVMet al., 2011, Reversible aggregation of responsive polymer-stabilized colloids and the pH-dependent formation of porous scaffolds, SOFT MATTER, Vol: 7, Pages: 7560-7566, ISSN: 1744-683X

Journal article

Ghadiali JE, Lowe SB, Stevens MM, 2011, Quantum-Dot-Based FRET Detection of Histone Acetyltransferase Activity, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol: 50, Pages: 3417-3420, ISSN: 1433-7851

Journal article

Gupta S, Andresen H, Stevens MM, 2011, Single-step kinase inhibitor screening using a peptide-modified gold nanoparticle platform, CHEMICAL COMMUNICATIONS, Vol: 47, Pages: 2249-2251, ISSN: 1359-7345

Journal article

Andresen H, Gupta S, Stevens MM, 2011, Kinetic investigation of bioresponsive nanoparticle assembly as a function of ligand design, NANOSCALE, Vol: 3, Pages: 383-386, ISSN: 2040-3364

Journal article

Ji L, Jell G, Dong Y, Jones JR, Stevens MMet al., 2011, Template synthesis of ordered macroporous hydroxyapatite bioceramics, CHEMICAL COMMUNICATIONS, Vol: 47, Pages: 9048-9050, ISSN: 1359-7345

Journal article

Mahony O, Tsigkou O, Ionescu C, Minelli C, Ling L, Hanly R, Smith ME, Stevens MM, Jones JRet al., 2010, Silica-Gelatin Hybrids with Tailorable Degradation and Mechanical Properties for Tissue Regeneration, ADVANCED FUNCTIONAL MATERIALS, Vol: 20, Pages: 3835-3845, ISSN: 1616-301X

Journal article

Minelli C, Lowe SB, Stevens MM, 2010, Engineering Nanocomposite Materials for Cancer Therapy, SMALL, Vol: 6, Pages: 2336-2357, ISSN: 1613-6810

Journal article

Tang M, Dong Y, Stevens MM, Williams CKet al., 2010, Tailoring Polylactide Degradation: Copolymerization of a Carbohydrate Lactone and S,S-Lactide, Macromolecules, Vol: 43, Pages: 7556-7564, ISSN: 0024-9297

Journal article

Ghadiali JE, Cohen BE, Stevens MM, 2010, Protein Kinase-Actuated Resonance Energy Transfer in Quantum Dot-Peptide Conjugates, ACS NANO, Vol: 4, Pages: 4915-4919, ISSN: 1936-0851

Journal article

Gupta S, Andresen H, Ghadiali JE, Stevens MMet al., 2010, Kinase-Actuated Immunoaggregation of Peptide-Conjugated Gold Nanoparticles, SMALL, Vol: 6, Pages: 1509-1513, ISSN: 1613-6810

Journal article

Maher RC, Maier SA, Cohen LF, Koh L, Laromaine A, Dick JAG, Stevens MMet al., 2010, Exploiting SERS Hot Spots for Disease-Specific Enzyme Detection, JOURNAL OF PHYSICAL CHEMISTRY C, Vol: 114, Pages: 7231-7235, ISSN: 1932-7447

Journal article

Swain RJ, Kemp SJ, Goldstraw P, Tetley TD, Steyens MMet al., 2010, Assessment of Cell Line Models of Primary Human Cells by Raman Spectral Phenotyping, BIOPHYSICAL JOURNAL, Vol: 98, Pages: 1703-1711, ISSN: 0006-3495

Journal article

Evans ND, Gentleman E, Chen X, Roberts CJ, Polak JM, Stevens MMet al., 2010, Extracellular matrix-mediated osteogenic differentiation of murine embryonic stem cells, BIOMATERIALS, Vol: 31, Pages: 3244-3252, ISSN: 0142-9612

Journal article

Gentleman E, Fredholm YC, Jell G, Lotfibakhshaiesh N, O'Donnell MD, Hill RG, Stevens MMet al., 2010, The effects of strontium-substituted bioactive glasses on osteoblasts and osteoclasts in vitro, Biomaterials, Vol: 31, Pages: 3949-3956, ISSN: 1878-5905

Journal article

Dong Y, Yong T, Liao S, Chan CK, Stevens MM, Ramakrishna Set al., 2010, Distinctive Degradation Behaviors of Electrospun Polyglycolide, Poly(DL-Lactide-<i>co</i>-Glycolide), and Poly(L-Lactide-<i>co</i>-ε-Caprolactone) Nanofibers Cultured With/Without Porcine Smooth Muscle Cells, TISSUE ENGINEERING PART A, Vol: 16, Pages: 283-298, ISSN: 1937-3341

Journal article

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