Imperial College London
Alternate

Professor Molly Stevens

Faculty of Engineering, Department of Materials

Professor of Biomedical Materials and Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Higgins:2020:10.1002/admt.202000384,
author = {Higgins, S and Lo, Fiego A and Patrick, I and Creamer, A and Stevens, M},
doi = {10.1002/admt.202000384},
journal = {Advanced Materials Technologies},
pages = {1--35},
title = {Organic bioelectronics: using highly conjugated polymers to interface with biomolecules, cells and tissues in the human body},
url = {http://dx.doi.org/10.1002/admt.202000384},
volume = {5},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Conjugated polymers exhibit interesting material and optoelectronic properties that makethem well-suited to the development of biointerfaces. Their biologically relevant mechanicalcharacteristics, ability to be chemically modified, and mixed electronic and ionic chargetransport are captured within the diverse field of organic bioelectronics. Conjugated polymershave been used in wide range of device architectures, and cell and tissue scaffolds. Thesedevices enable biosensing of many biomolecules, such as metabolites, nucleic acids and more.Devices can be used to both stimulate and sense the behavior of cells and tissues. Similarly,tissue interfaces permit interaction with complex organs, aiding both fundamental biologicalunderstanding and providing new opportunities for stimulating regenerative behaviors andbioelectronic based therapeutics. Applications of these materials are broad, and muchcontinues to be uncovered about their fundamental properties. This report covers the currentunderstanding of the fundamentals of conjugated polymer biointerfaces and their interactionswith biomolecules, cells and tissues in the human body. An overview of current materials anddevices is presented, along with highlighted major in vivo and in vitro applications. Finally,open research questions and opportunities are discussed.
AU  - Higgins,S
AU  - Lo,Fiego A
AU  - Patrick,I
AU  - Creamer,A
AU  - Stevens,M
DO  - 10.1002/admt.202000384
EP  - 35
PY  - 2020///
SN  - 2365-709X
SP  - 1
TI  - Organic bioelectronics: using highly conjugated polymers to interface with biomolecules, cells and tissues in the human body
T2  - Advanced Materials Technologies
UR  - http://dx.doi.org/10.1002/admt.202000384
UR  - https://onlinelibrary.wiley.com/doi/10.1002/admt.202000384
UR  - http://hdl.handle.net/10044/1/82301
VL  - 5
ER  -
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