Imperial College London
Alternate

Professor Molly Stevens

Faculty of Engineering, Department of Materials

Professor of Biomedical Materials and Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Lin:2017:10.1002/anie.201610976,
author = {Lin, Y and Pashuck, ET and Thomas, MR and Amdursky, N and Wang, S-T and Chow, LW and Stevens, MM},
doi = {10.1002/anie.201610976},
journal = {ANGEWANDTE CHEMIE-INTERNATIONAL EDITION},
pages = {2361--2365},
title = {Plasmonic chirality imprinting on nucleobase-displaying supramolecular nanohelices by metal-nucleobase recognition},
url = {http://dx.doi.org/10.1002/anie.201610976},
volume = {56},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Supramolecular self-assembly is an important process that enables the conception of complex structures mimicking biological motifs. Herein, we constructed helical fibrils through chiral self-assembly of nucleobase–peptide conjugates (NPCs), where achiral nucleobases are helically displayed on the surface of fibrils, comparable to polymerized nucleic acids. Selective binding between DNA and the NPC fibrils was observed with fluorescence polarization. Taking advantage of metal–nucleobase recognition, we highlight the possibility of deposition/assembly of plasmonic nanoparticles onto the fibrillar constructs. In this approach, the supramolecular chirality of NPCs can be adaptively imparted to metallic nanoparticles, covering them to generate structures with plasmonic chirality that exhibit significantly improved colloidal stability. The self-assembly of rationally designed NPCs into nanohelices is a promising way to engineer complex, optically diverse nucleobase-derived nanomaterials.
AU  - Lin,Y
AU  - Pashuck,ET
AU  - Thomas,MR
AU  - Amdursky,N
AU  - Wang,S-T
AU  - Chow,LW
AU  - Stevens,MM
DO  - 10.1002/anie.201610976
EP  - 2365
PY  - 2017///
SN  - 1433-7851
SP  - 2361
TI  - Plasmonic chirality imprinting on nucleobase-displaying supramolecular nanohelices by metal-nucleobase recognition
T2  - ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
UR  - http://dx.doi.org/10.1002/anie.201610976
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000395566600019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/45700
VL  - 56
ER  -
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