Imperial College London
Alternate

Professor Molly Stevens

Faculty of Engineering, Department of Materials

Professor of Biomedical Materials and Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Rizzo:2017:10.1016/j.snb.2017.09.018,
author = {Rizzo, R and Alvaro, M and Danz, N and Napione, L and Descrovi, E and Schmieder, S and Sinibaldi, A and Chandrawati, R and Rana, S and Munzert, P and Schubert, T and Maillart, E and Anopchenko, A and Rivolo, P and Mascioletti, A and Sonntag, F and Stevens, MM and Bussolino, F and Michelotti, F},
doi = {10.1016/j.snb.2017.09.018},
journal = {Sensors and Actuators B: Chemical},
pages = {2143--2150},
title = {Bloch surface wave label-free and fluorescence platform for the detection of VEGF biomarker in biological matrices},
url = {http://dx.doi.org/10.1016/j.snb.2017.09.018},
volume = {255},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We report on the detection of an angiogenic molecule Vascular Endothelial Growth Factor (VEGF) in different biological matrices by means of a new integrated biosensing platform exploiting the properties of Bloch surface waves. The new platform takes advantage of a tandem configuration, in which both label-free and enhanced fluorescence detection are implemented. Specifically designed one dimensional photonic crystals were deposited directly on disposable and low cost plastic biochips. A direct sandwich immunoassay was used to detect VEGF in buffer, cell culture supernatant and human plasma at low concentration (ng/mL). The platform enabled the detection of VEGF in all three matrices with high resolution, fast turnaround time (30 min) and in close agreement with the results of enzyme linked immunosorbent assays.
AU  - Rizzo,R
AU  - Alvaro,M
AU  - Danz,N
AU  - Napione,L
AU  - Descrovi,E
AU  - Schmieder,S
AU  - Sinibaldi,A
AU  - Chandrawati,R
AU  - Rana,S
AU  - Munzert,P
AU  - Schubert,T
AU  - Maillart,E
AU  - Anopchenko,A
AU  - Rivolo,P
AU  - Mascioletti,A
AU  - Sonntag,F
AU  - Stevens,MM
AU  - Bussolino,F
AU  - Michelotti,F
DO  - 10.1016/j.snb.2017.09.018
EP  - 2150
PY  - 2017///
SN  - 0925-4005
SP  - 2143
TI  - Bloch surface wave label-free and fluorescence platform for the detection of VEGF biomarker in biological matrices
T2  - Sensors and Actuators B: Chemical
UR  - http://dx.doi.org/10.1016/j.snb.2017.09.018
UR  - http://hdl.handle.net/10044/1/57168
VL  - 255
ER  -
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