Imperial College London

DrMarkSullivan

Faculty of MedicineDepartment of Surgery & Cancer

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 2133mark.sullivan Website

 
 
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Location

 

G-027Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

112 results found

Brew O, Sullivan MHF, 2017, Oxygen and tissue culture affect placental gene expression, PLACENTA, Vol: 55, Pages: 13-20, ISSN: 0143-4004

JOURNAL ARTICLE

Brew O, Sullivan MHF, Woodman A, 2016, Comparison of Normal and Pre-Eclamptic Placental Gene Expression: A Systematic Review with Meta-Analysis, PLOS ONE, Vol: 11, ISSN: 1932-6203

JOURNAL ARTICLE

Heyer-Chauhan N, Ovbude IJ, Hills AA, Sullivan MH, Hills FAet al., 2014, Placental syndecan-1 and sulphated glycosaminoglycans are decreased in preeclampsia, JOURNAL OF PERINATAL MEDICINE, Vol: 42, Pages: 329-338, ISSN: 0300-5577

JOURNAL ARTICLE

Hills FA, Iles RK, Sullivan MH, 2013, Differential proteolysis of insulin-like growth factor binding protein-1 (IGFBP-1) in pregnancy, JOURNAL OF PERINATAL MEDICINE, Vol: 41, Pages: 241-249, ISSN: 0300-5577

JOURNAL ARTICLE

Hills FA, Mehmet H, Sullivan MH, 2012, Insulin-like growth factor-II and heparin are anti-apoptotic survival factors in human villous cytotrophoblast, EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, Vol: 163, Pages: 11-16, ISSN: 0301-2115

JOURNAL ARTICLE

Sullivan MH, 2009, Comparison of intact tissues and isolated cells from human fetal membranes, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 200, Pages: E14-E14, ISSN: 0002-9378

JOURNAL ARTICLE

Galea P, Barigye O, Wee L, Jain V, Sullivan M, Fisk NMet al., 2008, The placenta contributes to activation of the renin angiotensin system in twin-twin transfusion syndrome, PLACENTA, Vol: 29, Pages: 734-742, ISSN: 0143-4004

JOURNAL ARTICLE

Sullivan MHF, 2008, Bacteria in placenta and fetal membranes., Am J Obstet Gynecol, Vol: 199, Pages: e13-e14

JOURNAL ARTICLE

Al-Asmakh M, Race H, Tan S, Sullivan MHFet al., 2007, The effects of oxygen concentration on in vitro output of prostaglandin E-2 and interleukin-6 from human fetal membranes, MOLECULAR HUMAN REPRODUCTION, Vol: 13, Pages: 197-201, ISSN: 1360-9947

JOURNAL ARTICLE

Albrecht C, Soumian S, Tetlow N, Patel P, Sullivan MHF, Lakasing L, Nicolaides K, Williamson Cet al., 2007, Placental ABCA1 expression is reduced in primary antiphospholipid syndrome compared to pre-eclampsia and controls, PLACENTA, Vol: 28, Pages: 701-708, ISSN: 0143-4004

JOURNAL ARTICLE

Brew O, Lakasing L, Sullivan M, 2007, Differential activity of histidine decarboxylase in normal and pre-eclamptic placentae, PLACENTA, Vol: 28, Pages: 585-587, ISSN: 0143-4004

JOURNAL ARTICLE

Brew O, Sullivan M, 2007, Histamine regulates placental diamine oxidase mrna expression - Evidence for a feedback loop decreasing histamine production in pregnancy?, 13th International-Federation-of-Placenta-Association Meeting, Publisher: W B SAUNDERS CO LTD, Pages: A71-A71, ISSN: 0143-4004

CONFERENCE PAPER

Wee LY, Sullivan M, Humphries K, Fisk NMet al., 2007, Longitudinal blood flow in shared (arteriovenous anastomoses) and non-shared cotyledons in monochorionic placentae, PLACENTA, Vol: 28, Pages: 516-522, ISSN: 0143-4004

JOURNAL ARTICLE

Brew O, Sullivan MHF, 2006, The links between maternal histamine levels and complications of human pregnancy, JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Vol: 72, Pages: 94-107, ISSN: 0165-0378

JOURNAL ARTICLE

Hills FA, Abrahams VM, Gonzalez-Timon B, Francis J, Cloke B, Hinkson L, Rai R, Mor G, Regan L, Sullivan M, Lam EWF, Brosens JJet al., 2006, Heparin prevents programmed cell death in human trophoblast, MOLECULAR HUMAN REPRODUCTION, Vol: 12, Pages: 237-243, ISSN: 1360-9947

JOURNAL ARTICLE

Wee LY, Sebire NJ, Bhundia J, Sullivan M, Fisk NMet al., 2006, Histomorphometric characterisation of shared and non-shared cotyledonary villus territories of monochorionic placentae in relation to pregnancy complications, PLACENTA, Vol: 27, Pages: 475-482, ISSN: 0143-4004

JOURNAL ARTICLE

Bar J, Ben-Haroush A, Feldberg D, Hod M, Lahav J, Sullivan MHet al., 2005, Interaction between platelets and cytokines - A possible role in the pathogenesis of preeclampsia, International Symposium on Womens Health Issues in Thrombosis and Hemostasis, Publisher: PERGAMON-ELSEVIER SCIENCE LTD, Pages: 110-110, ISSN: 0049-3848

CONFERENCE PAPER

Cahill RJ, Tan S, Dougan G, O'Gaora P, Pickard D, Kennea N, Sullivan MHF, Feldman RG, Edwards ADet al., 2005, Universal DNA primers amplify bacterial DNA from human fetal membranes and link Fusobacterium nucleatum with prolonged preterm membrane rupture, MOLECULAR HUMAN REPRODUCTION, Vol: 11, Pages: 761-766, ISSN: 1360-9947

JOURNAL ARTICLE

Steel JH, Malatos S, Kennea N, Edwards AD, Miles L, Duggan P, Reynolds PR, Feldman RG, Sullivan MHFet al., 2005, Bacteria and inflammatory cells in fetal membranes do not always cause preterm labor, PEDIATRIC RESEARCH, Vol: 57, Pages: 404-411, ISSN: 0031-3998

JOURNAL ARTICLE

Steel JH, O'Donoghue K, Kennea NL, Sullivan MHF, Edwards ADet al., 2005, Maternal origin of inflammatory leukocytes in preterm fetal membranes, shown by fluorescence in situ hybridisation, PLACENTA, Vol: 26, Pages: 672-677, ISSN: 0143-4004

JOURNAL ARTICLE

Wee LY, Sebire NJ, Sullivan M, Fisk NMet al., 2005, Histomorphometric characterisation of shared and non-shared cotyledonary villus territories in monochorionic placentae in relation to pregnancy complications, 3rd Joint Meeting of the British Division of the International-Academy-of-Pahtology/Meeting of the Pathological-Society-of-Great-Britian-and-Ireland, Publisher: JOHN WILEY & SONS LTD, Pages: 1-1, ISSN: 0022-3417

CONFERENCE PAPER

Anim-Nyame N, Sooranna SR, Johnson MR, Sullivan MH, Gamble J, Steer PJet al., 2004, Impaired retrograde transmission of vasodilatory signals via the endothelium in pre-eclampsia: a cause of reduced tissue blood flow?, CLINICAL SCIENCE, Vol: 106, Pages: 19-25, ISSN: 0143-5221

JOURNAL ARTICLE

Hills FA, Bennett PR, Sullivan MH, 2004, Effect of thrombin, heparin and aspirin on trophoblast apoptosis., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Publisher: ELSEVIER SCIENCE INC, Pages: 348A-348A, ISSN: 1071-5576

CONFERENCE PAPER

Hills FA, Elder MG, Chard T, Sullivan MHFet al., 2004, Regulation of human villous trophoblast by insulin-like growth factors and insulin-like growth factor-binding protein-1, JOURNAL OF ENDOCRINOLOGY, Vol: 183, Pages: 487-496, ISSN: 0022-0795

JOURNAL ARTICLE

Sullivan MHF, 2004, Endocrine cell lines from the placenta, MOLECULAR AND CELLULAR ENDOCRINOLOGY, Vol: 228, Pages: 103-119, ISSN: 0303-7207

JOURNAL ARTICLE

Sullivan MHF, Steel J, Kennea N, Feldman RG, Edwards ADet al., 2004, The role of intrauterine bacteria in brain injury, ACTA PAEDIATRICA, Vol: 93, Pages: 4-5, ISSN: 0803-5253

JOURNAL ARTICLE

, 2004, Abstracts of the Autumn Meeting of the Neonatal Society. 20 November 2003, London, United Kingdom., Early Hum Dev, Vol: 77, Pages: 109-127, ISSN: 0378-3782

JOURNAL ARTICLE

Anim-Nyame N, Gamble J, Sooranna SR, Johnson MR, Sullivan MH, Steer PJet al., 2003, Evidence of impaired microvascular function in pre-eclampsia: a non-invasive study, CLINICAL SCIENCE, Vol: 104, Pages: 405-412, ISSN: 0143-5221

JOURNAL ARTICLE

Sawdy R, Pan H, Sullivan M, Bennett Pet al., 2003, Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis., J Obstet Gynaecol, Vol: 23, Pages: 239-243, ISSN: 0144-3615

Increased expression of the inducible isoform of cyclo-oxygenase (COX-2) and prostaglandin output from fetal membranes is a key stage in human parturition. Prostaglandin production can be inhibited by non-steroidal anti-inflammatory drugs (NSAIDs), but these may also inhibit cyclo-oxygenase enzymes in fetal tissues, and hence cause potentially serious side effects. We have compared the concentrations of NSAIDs that inhibit maximal PGE2 synthesis from intact human fetal membrane explants in vitro with those found in human plasma after standard anti-inflammatory treatment. The concentrations of all six drugs that caused a 50% inhibition of fetal membrane prostaglandin output were lower than average plasma levels achieved during treatment. This effect was greatest for nimesulide and indomethacin, indicating that these drugs require further study at low doses in vivo, as this could achieve the same tocolytic effect with diminished adverse fetal effect. These drugs were also the most potent inhibitors of fetal membrane prostaglandin output, consistent with their effects on COX-2 activity.

JOURNAL ARTICLE

Sawdy RJ, Sullivan MHF, Bennett PR, 2003, The effects of non-steroidal anti-inflammatory compounds on human myometrial contractility, EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, Vol: 109, Pages: 33-40, ISSN: 0301-2115

JOURNAL ARTICLE

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