Imperial College London
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Professor Mark Rehkämper

Faculty of Engineering, Department of Earth Science & Engineering

Professor of Isotope Geochemistry
 
 
 
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Contact

 

markrehk Website

 
 
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Location

 

451Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Moore:2017:10.1007/s00216-017-0240-y,
author = {Moore, RET and Larner, F and Coles, BJ and Rehkämper, M},
doi = {10.1007/s00216-017-0240-y},
journal = {Analytical and Bioanalytical Chemistry},
pages = {2941--2950},
title = {High precision zinc stable isotope measurement of certified biological reference materials using the double spike technique and multiple collector-ICP-MS},
url = {http://dx.doi.org/10.1007/s00216-017-0240-y},
volume = {409},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Biological reference materials with well-characterized stable isotope compositions are lacking in the field of ‘isotope biochemistry’, which seeks to understand bodily processes that rely on essential metals by determiningmetal stable isotope ratios. Here, we present Zn stable isotope data for six biological reference materials with certified trace metal concentrations, fish muscle, bovine muscle, pig kidney, human hair,human blood serum and human urine. Replicate analyses of multiple aliquots of each material achieved reproducibilities (2sd) of 0.04-0.13 ‰ for δ66/64Zn 22 (which denotes the deviation of the 66 Zn/64Zn ratio of a sample from a pure Zn reference material in  parts  per  1000).  This  implies  only  very  minor  isotopic  heterogeneities  within  the samples, rendering them suitable as quality control materials for Zn isotopeanalyses. This endorsement is reinforced by (i) the close agreement of our Zn isotope data for two of the samples (bovine 2 muscle and human blood serum) to previously published results for different batches of the same material and (ii) the similarity of the isotopic data for the samples (δ66/64Zn≈ –0.8 to 0.0 ‰) to previously  published  Zn  isotope results  for similar biological  materials. Further tests revealed that  the  applied Zn  separation  procedure is  sufficiently effective  to  enable  accurate  data acquisition even at  low mass  resolving power  (M/ΔM ≈ 400), as  measurements and  analyses conducted at much higher mass resolution (M/ΔM ≈ 8500) delivered essentially identicalresults.
AU  - Moore,RET
AU  - Larner,F
AU  - Coles,BJ
AU  - Rehkämper,M
DO  - 10.1007/s00216-017-0240-y
EP  - 2950
PY  - 2017///
SN  - 1618-2650
SP  - 2941
TI  - High precision zinc stable isotope measurement of certified biological reference materials using the double spike technique and multiple collector-ICP-MS
T2  - Analytical and Bioanalytical Chemistry
UR  - http://dx.doi.org/10.1007/s00216-017-0240-y
UR  - http://hdl.handle.net/10044/1/44347
VL  - 409
ER  -
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