Imperial College London

Dr Matthew R. Lewis

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Director of Metabolic Profiling - COO NPC



+44 (0)20 7594 3108matthew.lewis




660Sir Alexander Fleming BuildingSouth Kensington Campus





As the Chief Operations Officer for the MRC-NIHR Phenome Centre (NPC), Clinical Phenotyping Centre (CPC), and the Director of Metabolic Profiling  for the Division of Computational and Systems Medicine, I am responsible for operational management and oversight of all research collaborations from design to delivery, as well as the development and execution of analytical research strategies. Within the NPC, our focus is on high precision analysis of large sample cohorts from molecular epidemiology studies, while at the CPC our focus is on smaller clinically derived cohorts analysed using both established and developing technologies.



Sands C, Wolfer A, DS Correia G, et al., 2019, The nPYc-Toolbox, a Python module for the pre-processing, quality-control, and analysis of metabolic profiling datasets, Bioinformatics, Vol:35, ISSN:1367-4803, Pages:5359-5360

Wang X, Nijman R, Camuzeaux S, et al., 2019, Plasma lipid profiles discriminate bacterial from viral infection in febrile children, Scientific Reports, Vol:9, ISSN:2045-2322

Whiley L, Chekmeneva E, Berry DJ, et al., 2019, Systematic isolation and structure elucidation of urinary metabolites optimized for the analytical-scale molecular profiling laboratory, Analytical Chemistry, Vol:91, ISSN:0003-2700, Pages:8873-8882

Gafson AR, Savva C, Thorne T, et al., 2019, Breaking the cycle: reversal of flux in the tricarboxylic acid cycle by dimethyl fumarate, Neurology, Neuroimmunology and Neuroinflammation, Vol:6, ISSN:2332-7812

Whiley LW, Nye L, Grant I, et al., 2019, Ultrahigh-performance liquid chromatography tandem mass spectrometry with electrospray ionization quantification of tryptophan metabolites and markers of gut health in serum and plasmaapplication to clinical and epidemiology cohorts, Analytical Chemistry, Vol:91, ISSN:0003-2700, Pages:5207-5216

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