Publications
264 results found
Li J-B, Tang C, Dai M, et al., 2014, A New Head Phantom With Realistic Shape and Spatially Varying Skull Resistivity Distribution, IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, Vol: 61, Pages: 254-263, ISSN: 0018-9294
- Author Web Link
- Cite
- Citations: 23
Cheng Y, Li S, Eckersley RJ, et al., 2013, Viscosity measurement based on shear-wave laser speckle contrast analysis, JOURNAL OF BIOMEDICAL OPTICS, Vol: 18, ISSN: 1083-3668
- Author Web Link
- Open Access Link
- Cite
- Citations: 7
Viessmann OM, Eckersley RJ, Christensen-Jeffries K, et al., 2013, Acoustic super-resolution with ultrasound and microbubbles, PHYSICS IN MEDICINE AND BIOLOGY, Vol: 58, Pages: 6447-6458, ISSN: 0031-9155
- Author Web Link
- Cite
- Citations: 188
Zhou B, Fraser KH, Poelma C, et al., 2013, ULTRASOUND IMAGING VELOCIMETRY: EFFECT OF BEAM SWEEPING ON VELOCITY ESTIMATION, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 39, Pages: 1672-1681, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 22
Hosny NA, Mohamedi G, Rademeyer P, et al., 2013, Mapping microbubble viscosity using fluorescence lifetime imaging of molecular rotors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 110, Pages: 9225-9230, ISSN: 0027-8424
- Author Web Link
- Open Access Link
- Cite
- Citations: 112
Casey J, Sennoga C, Mulvana H, et al., 2013, SINGLE BUBBLE ACOUSTIC CHARACTERIZATION AND STABILITY MEASUREMENT OF ADHERENT MICROBUBBLES, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 39, Pages: 903-914, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 9
Papadopoulou V, Eckersley RJ, Balestra C, et al., 2013, A critical review of physiological bubble formation in hyperbaric decompression, Advances in Colloid and Interface Science, Vol: 191–192, Pages: 22-30, ISSN: 1873-3727
Fan T, Liu Z, Zhang D, et al., 2013, Comparative Study of Lesions Created by High-Intensity Focused Ultrasound Using Sequential Discrete and Continuous Scanning Strategies, IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, Vol: 60, Pages: 763-769, ISSN: 0018-9294
- Author Web Link
- Cite
- Citations: 14
Owen J, Zhou B, Rademeyer P, et al., 2012, Understanding the structure and mechanism of formation of a new magnetic microbubble formulation, Theranostics, Vol: 2, Pages: 1127-1139, ISSN: 1838-7640
Loughran J, Sennoga C, Eckersley RJ, et al., 2012, Effect of ultrasound on adherent microbubble contrast agents, PHYSICS IN MEDICINE AND BIOLOGY, Vol: 57, Pages: 6999-7014, ISSN: 0031-9155
- Author Web Link
- Open Access Link
- Cite
- Citations: 4
Poelma C, van der Mijle RME, Mari JM, et al., 2012, Ultrasound imaging velocimetry: Toward reliable wall shear stress measurements, EUROPEAN JOURNAL OF MECHANICS B-FLUIDS, Vol: 35, Pages: 70-75, ISSN: 0997-7546
- Author Web Link
- Cite
- Citations: 41
Mulvana H, Browning RJ, Tang M-X, et al., 2012, ALBUMIN COATED MICROBUBBLE OPTIMIZATION: CUSTOM FABRICATION AND COMPREHENSIVE CHARACTERIZATION, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 38, Pages: 1599-1607, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 4
Cheng Y, Li R, Li S, et al., 2012, SHEAR WAVE ELASTICITY IMAGING BASED ON ACOUSTIC RADIATION FORCE AND OPTICAL DETECTION, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 38, Pages: 1637-1645, ISSN: 0301-5629
- Author Web Link
- Open Access Link
- Cite
- Citations: 18
Mulvana H, Stride E, Tang M-X, et al., 2012, THE INFLUENCE OF GAS SATURATION ON MICROBUBBLE STABILITY, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 38, Pages: 1097-1100, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 23
Browning RJ, Mulvana H, Tang M-X, et al., 2012, EFFECT OF ALBUMIN AND DEXTROSE CONCENTRATION ON ULTRASOUND AND MICROBUBBLE MEDIATED GENE TRANSFECTION <i>IN VIVO</i>, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 38, Pages: 1067-1077, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 13
Loughran J, Eckersley RJ, Tang M-X, 2012, Modeling non-spherical oscillations and stability of acoustically driven shelled microbubbles, JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol: 131, Pages: 4349-4357, ISSN: 0001-4966
- Author Web Link
- Cite
- Citations: 10
Mulvana H, Eckersley RJ, Tang M-X, et al., 2012, THEORETICAL AND EXPERIMENTAL CHARACTERISATION OF MAGNETIC MICROBUBBLES, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 38, Pages: 864-875, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 27
Sennoga CA, Yeh JSM, Alter J, et al., 2012, EVALUATION OF METHODS FOR SIZING AND COUNTING OF ULTRASOUND CONTRAST AGENTS, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 38, Pages: 834-845, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 39
Stride E, Owen J, Mulvana H, et al., 2012, Magnetic microbubbles for localised imaging and drug delivery: Development, characterisation and preliminary application in vivo., J Acoust Soc Am, Vol: 131
The use of coated microbubbles in therapeutic applications, in particular drug delivery and gene therapy, has become a highly active area of research. There remain, however, some significant challenges to be overcome in order to fully realise the potential of microbubbles in these applications. In particular, the difficulty in controlling the concentration of microbubbles at a given site and in ensuring sufficient proximity between bubbles and target cells, has frequently led to disappointing results from in vivo studies. Recent work has indicated that incorporating magnetic nanoparticles into the microbubble coating may provide an effective strategy for overcoming these challenges. Further investigation to fully understand the mechanisms of enhancement and hence optimise the delivery protocols is however required and this is the aim of the present study. Results will be presented from flow phantom studies demonstrating manipulation of bubble suspensions under physiological flow conditions, from high speed imaging used to investigate the dynamic behaviour of single microbubbles and theoretical modelling conducted to support and interpret the experimental findings. Finally results demonstrating in vivo transfection in a mouse model will be presented confirming successful localisation of the transfection site.
Song L, Cheng Y, Li R, et al., 2012, Imaging ultrasound field and shear wave propagation using acousto-optic laser speckle contrast analysis (AO-LASCA), Conference on Photons Plus Ultrasound - Imaging and Sensing/Photonics West BiOS Symposium, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X
Browning RJ, Tang M-X, Eckersley RJ, 2012, The Effect of Glucosamine on the Acoustic and Binding Properties of Albumin-based Microbubbles (Work in Progress), 2012 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), Pages: 2294-2297, ISSN: 1948-5719
Stride E, Mulvana H, Eckersley R, et al., 2012, Magnetic Microbubbles, MAGNETIC NANOPARTICLES: FROM FABRICATION TO CLINICAL APPLICATIONS, Editors: Thanh, Publisher: CRC PRESS-TAYLOR & FRANCIS GROUP, Pages: 499-522, ISBN: 978-1-4398-6932-1
Zhang Y-L, Zheng H-R, Tang M-X, et al., 2011, Effect of secondary radiation force on aggregation between encapsulated microbubbles, CHINESE PHYSICS B, Vol: 20, ISSN: 1674-1056
- Author Web Link
- Cite
- Citations: 8
Browning RJ, Mulvana H, Tang M, et al., 2011, INFLUENCE OF NEEDLE GAUGE ON <i>IN VIVO</i> ULTRASOUND AND MICROBUBBLE-MEDIATED GENE TRANSFECTION, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 37, Pages: 1531-1537, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 18
Mulvana H, Stride E, Tang M, et al., 2011, TEMPERATURE-DEPENDENT DIFFERENCES IN THE NONLINEAR ACOUSTIC BEHAVIOR OF ULTRASOUND CONTRAST AGENTS REVEALED BY HIGH-SPEED IMAGING AND BULK ACOUSTICS, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 37, Pages: 1509-1517, ISSN: 0301-5629
- Author Web Link
- Cite
- Citations: 21
Elson DS, Li R, Dunsby C, et al., 2011, Ultrasound-mediated optical tomography: a review of current methods, INTERFACE FOCUS, Vol: 1, Pages: 632-648, ISSN: 2042-8898
- Author Web Link
- Open Access Link
- Cite
- Citations: 60
Tang M-X, Mulvana H, Gauthier T, et al., 2011, Quantitative contrast-enhanced ultrasound imaging: a review of sources of variability, INTERFACE FOCUS, Vol: 1, Pages: 520-539, ISSN: 2042-8898
- Author Web Link
- Cite
- Citations: 214
Xu S, Dai M, Xu C, et al., 2011, Performance Evaluation of Five Types of Ag/AgCl Bio-Electrodes for Cerebral Electrical Impedance Tomography, ANNALS OF BIOMEDICAL ENGINEERING, Vol: 39, Pages: 2059-2067, ISSN: 0090-6964
- Author Web Link
- Cite
- Citations: 33
Li R, Elson DS, Dunsby C, et al., 2011, Effects of acoustic radiation force and shear waves for absorption and stiffness sensing in ultrasound modulated optical tomography., Opt Express, Vol: 19, Pages: 7299-7311
Ultrasound-modulated optical tomography (UOT) combines optical contrast with ultrasound spatial resolution and has great potential for soft tissue functional imaging. One current problem with this technique is the weak optical modulation signal, primarily due to strong optical scattering in diffuse media and minimal acoustically induced modulation. The acoustic radiation force (ARF) can create large particle displacements in tissue and has been shown to be able to improve optical modulation signals. However, shear wave propagation induced by the ARF can be a significant source of nonlocal optical modulation which may reduce UOT spatial resolution and contrast. In this paper, the time evolution of shear waves was examined on tissue mimicking-phantoms exposed to 5 MHz ultrasound and 532 nm optical radiation and measured with a CCD camera. It has been demonstrated that by generating an ARF with an acoustic burst and adjusting both the timing and the exposure time of the CCD measurement, optical contrast and spatial resolution can be improved by ~110% and ~40% respectively when using the ARF rather than 5 MHz ultrasound alone. Furthermore, it has been demonstrated that this technique simultaneously detects both optical and mechanical contrast in the medium and the optical and mechanical contrast can be distinguished by adjusting the CCD exposure time.
Tang M-X, Loughran J, Stride E, et al., 2011, Effect of bubble shell nonlinearity on ultrasound nonlinear propagation through microbubble populations, JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, Vol: 129, Pages: EL76-EL82, ISSN: 0001-4966
- Author Web Link
- Cite
- Citations: 17
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.