Imperial College London
Alternate

Michael A Crawford PhD, FRSB, FRCPath

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Visiting Professor
 
 
 
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Contact

 

+44 (0)7725 250 541michael.crawford Website CV

 
 
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Location

 

H 3.34Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sumich:2013:10.1016/j.plefa.2013.03.004,
author = {Sumich, AL and Matsudaira, T and Heasman, B and Gow, RV and Ibrahimovic, A and Ghebremeskel, K and Crawford, MA and Taylor, E},
doi = {10.1016/j.plefa.2013.03.004},
journal = {Prostaglandins Leukot Essent Fatty Acids},
pages = {431--436},
title = {Fatty acid correlates of temperament in adolescent boys with attention deficit hyperactivity disorder.},
url = {http://dx.doi.org/10.1016/j.plefa.2013.03.004},
volume = {88},
year = {2013}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Atypical fatty acid metabolism has been reported in attention deficit hyperactivity disorder (ADHD), however, its relationship with temperament in this population is unclear. The current study investigated the association between blood levels of fatty acids implicated in brain structure and function (omega-3, omega-6, omega-9) and personality traits of stability (neuroticism, conscientiousness and agreeableness) and plasticity (extraversion and openness). Twenty right-handed adolescent boys with ADHD completed a self-report NEO-FFI personality questionnaire, and had fatty acid content assessed from red blood using gas chromatography. Pearson's correlations showed no significant associations between omega-3 levels and personality. After correction for multiple comparisons, Adrenic Acid (C22:4n6) was inversely associated with stability. Oleic acid (C18:1n9) was positively associated with plasticity. Results are in line with a role of fatty acids in brain function. They suggest that those fatty acids that are involved in myelination (Adrenic, Oleic) have the strongest associations with temperament in adolescents with ADHD.
AU  - Sumich,AL
AU  - Matsudaira,T
AU  - Heasman,B
AU  - Gow,RV
AU  - Ibrahimovic,A
AU  - Ghebremeskel,K
AU  - Crawford,MA
AU  - Taylor,E
DO  - 10.1016/j.plefa.2013.03.004
EP  - 436
PY  - 2013///
SP  - 431
TI  - Fatty acid correlates of temperament in adolescent boys with attention deficit hyperactivity disorder.
T2  - Prostaglandins Leukot Essent Fatty Acids
UR  - http://dx.doi.org/10.1016/j.plefa.2013.03.004
UR  - https://www.ncbi.nlm.nih.gov/pubmed/23566869
VL  - 88
ER  -
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