I am a non-clinical lecturer in Physiology within the Section of Anaesthetics, Pain Medicine and Intensive Care. I received my PhD from Imperial College (St. Mary''s Hospital) in 1998 and following postdoctoral stints at King''s College London and Queen Mary University of London, rejoined Imperial in 2001.
I am a member of the Critical Care Research group headed by Prof Masao Takata, and have a major interest in understanding the science behind pulmonary aspects of critical care. In particular my main focus is the process by which the inflammatory response influences the development of acute lung injury within the Intensive Care unit. Areas of specific interest include -
- improved modelling
- mechanisms of ventilator-induced lung injury (VILI)
- TNF signaling during acute lung injury
- monocyte/macrophage involvement during VILI
I am Course Director for the BSc in Surgery & Anaesthesia, and joint lead for the Anaesthetics, Pain Medicine and Intensive Care (APMIC) stream of the MRes in Biomedical Research.
- GlaxoSmithKline. 2008 -
et al., 2019, ATP redirects cytokine trafficking and promotes novel membrane TNF signalling via microvesicles, Faseb Journal, ISSN:0892-6638
Wilson M, Takata M, 2019, Mechanical Ventilation in Mice: Does Longer Equal Better?, American Journal of Respiratory Cell and Molecular Biology, Vol:60, ISSN:1044-1549, Pages:137-138
Koh MW, Takata M, Wilson MR, 2019, Cyclophilin A as a Novel Mediator in Acute Lung Injury, International Conference of the American-Thoracic-Society, AMER THORACIC SOC, ISSN:1073-449X
et al., 2018, Late Breaking Abstract - Intra-alveolar neutrophil-derived microvesicles: a biomarker of COPD severity, 28th International Congress of the European-Respiratory-Society (ERS), EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN:0903-1936
Du W, Takata M, Wilson MR, 2018, Activation of lung-marginated monocytes in initiating ventilator-induced extra-pulmonary inflammation, British-Journal-of-Anaesthesia (BJA) Research Forum, ELSEVIER SCI LTD, Pages:E25-E26, ISSN:0007-0912