I am a non-clinical lecturer in Physiology within the Section of Anaesthetics, Pain Medicine and Intensive Care. I received my PhD from Imperial College (St. Mary''s Hospital) in 1998 and following postdoctoral stints at King''s College London and Queen Mary University of London, rejoined Imperial in 2001.
I am a member of the Critical Care Research group headed by Prof Masao Takata, and have a major interest in understanding the science behind pulmonary aspects of critical care. In particular my main focus is the process by which the inflammatory response influences the development of acute lung injury within the Intensive Care unit. Areas of specific interest include -
- improved modelling
- mechanisms of ventilator-induced lung injury (VILI)
- TNF signaling during acute lung injury
- monocyte/macrophage involvement during VILI
I am Course Director for the BSc in Surgery & Anaesthesia, and joint lead for the Anaesthetics, Pain Medicine and Intensive Care (APMIC) stream of the MRes in Biomedical Research.
- GlaxoSmithKline. 2008 -
Takata M, Wilson M, Editorial View: If we ask a mouse about biotrauma, will it give us a sensibleanswer?, Anesthesiology, ISSN:1528-1175
et al., 2017, High-Fat Feeding Protects Mice From Ventilator-Induced Lung Injury, Via Neutrophil-Independent Mechanisms, Critical Care Medicine, Vol:45, ISSN:0090-3493, Pages:E831-E839
Takata M, Wilson MR, 2017, If We Ask a Mouse about Biotrauma, Will It Give Us a Sensible Answer?, Anesthesiology, Vol:126, ISSN:0003-3022, Pages:766-767
et al., 2017, Inhibition of TNF Receptor p55 By a Domain Antibody Attenuates the Initial Phase of Acid-Induced Lung Injury in Mice, Frontiers in Immunology, Vol:8, ISSN:1664-3224
et al., 2016, Alveolar macrophage-derived microvesicles mediate acute lung injury, Thorax, Vol:71, ISSN:0040-6376, Pages:1020-1029