I am a non-clinical lecturer in Physiology within the Section of Anaesthetics, Pain Medicine and Intensive Care. I received my PhD from Imperial College (St. Mary''s Hospital) in 1998 and following postdoctoral stints at King''s College London and Queen Mary University of London, rejoined Imperial in 2001.
I am a member of the Critical Care Research group headed by Prof Masao Takata, and have a major interest in understanding the science behind pulmonary aspects of critical care. In particular my main focus is the process by which the inflammatory response influences the development of acute lung injury within the Intensive Care unit. Areas of specific interest include -
- improved modelling
- mechanisms of ventilator-induced lung injury (VILI)
- TNF signaling during acute lung injury
- monocyte/macrophage involvement during VILI
I am Module Director for the ''Perioperative Medicine'' module which forms part of the BSc in Surgery & Anaesthesia.
- GlaxoSmithKline. 2008 -
Takata M, Wilson M, Editorial View: If we ask a mouse about biotrauma, will it give us a sensibleanswer?, Anesthesiology, ISSN:1528-1175
Takata M, Wilson MR, 2017, If We Ask a Mouse about Biotrauma, Will It Give Us a Sensible Answer?, Anesthesiology, Vol:126, ISSN:0003-3022, Pages:766-767
et al., 2017, High-Fat Feeding Protects Mice From Ventilator-Induced Lung Injury, Via Neutrophil-Independent Mechanisms, Critical Care Medicine, Vol:45, ISSN:0090-3493, Pages:E831-E839
et al., 2017, Inhibition of TNF Receptor p55 By a Domain Antibody Attenuates the Initial Phase of Acid-Induced Lung Injury in Mice, Frontiers in Immunology, Vol:8, ISSN:1664-3224
et al., 2016, Loss of epithelial G(q) and G(11) signaling inhibits TGF beta production but promotes IL-33-mediated macrophage polarization and emphysema, Science Signaling, Vol:9, ISSN:1945-0877