Publications
151 results found
Lane RE, Ilsley CDJ, Wallis W, et al., 2007, Percutaneous coronary intervention of a circumflex chronic total occlusion using an epicardial collateral retrograde approach, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 69, Pages: 842-844, ISSN: 1522-1946
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- Citations: 10
Dalby M, Roughton M, Ilsley C, 2007, Door-to-balloon time in acute myocardial infarction, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 356, Pages: 1475-1476, ISSN: 0028-4793
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- Citations: 1
La Manna A, Goktekin O, Fiscella D, et al., 2006, Which strategy should be used for acute ST-elevation myocardial infarction in patients aged more than 75 years?, JOURNAL OF CARDIOVASCULAR MEDICINE, Vol: 7, Pages: 388-396, ISSN: 1558-2027
Partridge J, McGahan G, Causton S, et al., 2006, Radiation dose reduction without compromise of image quality in cardiac angiography and intervention with the use of a flat panel detector without an antiscatter grid, HEART, Vol: 92, Pages: 507-510, ISSN: 1355-6037
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- Citations: 38
Recica H, Grocott-Mason R, Teoh M, et al., 2005, Impact of primary angioplasty (PPCI) programme on the management of patients presenting with ST-elevation myocardial infarction (STEMI) in a North West London borough, Annual Conference of G-MEX/MICC, Publisher: B M J PUBLISHING GROUP, Pages: A53-A53, ISSN: 1355-6037
Montalescot G, Chevalier B, Dalby MC, et al., 2005, Description of modern practices of percutaneous coronary intervention and identification of risk factors for adverse outcome in the French nationwide OPEN registry, HEART, Vol: 91, Pages: 89-+, ISSN: 1355-6037
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- Citations: 3
Dalby M, Montalescot G, Sollier CBD, et al., 2004, Eptifibatide provides additional platelet inhibition in non-ST-elevation myocardial infarction patients already treated with aspirin and clopidogrel - Results of the platelet activity extinction in non-Q-wave myocardial infarction with aspirin, clopidogrel, and eptifibatide (PEACE) study, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 43, Pages: 162-168, ISSN: 0735-1097
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- Citations: 56
Dalby M, Eltchaninoff H, Cribier A, 2003, Non-surgical aortic valve replacement, British Journal of Cardiology, Vol: 10, ISSN: 0969-6113
This article discusses percutaneous aortic valve replacement, a new technique developed to overcome the problem of restenosis of the native valve in patients treated with balloon aortic valvuloplasty. It describes the first four cases which have been undertaken using this new technique that show the potential for its development for more widespread use in the future.
Dalby M, Bouzamondo A, Lechat P, et al., 2003, Transfer for primary angioplasty versus immediate thrombolysis in acute myocardial infarction - A meta-analysis, CIRCULATION, Vol: 108, Pages: 1809-1814, ISSN: 0009-7322
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- Citations: 318
Dalby M, Davies J, Rakhit R, et al., 2003, Feasibility and safety of day-case transfemoral coronary stenting, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 60, Pages: 18-24, ISSN: 1522-1946
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- Citations: 20
Montalescot G, Bal-dit-Sollier C, Chibedi D, et al., 2003, Comparison of effects on markers of blood cell activation of <i>enoxaparin</i>, <i>dalteparin</i>, and unfractionated <i>heparin</i> in patients with unstable angina pectoris or non-ST-segment elevation acute myocardial infarction (The ARMADA study), AMERICAN JOURNAL OF CARDIOLOGY, Vol: 91, Pages: 925-930, ISSN: 0002-9149
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- Citations: 73
Dalby MCD, Banner NR, Tansley P, et al., 2003, Left ventricular function during support with an asynchronous pulsatile left ventricular assist device, JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 22, Pages: 292-300, ISSN: 1053-2498
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- Citations: 13
Luyt CE, Drobinski G, Dorent R, et al., 2003, Prognosis of moderate coronary artery lesions in heart transplant patients, JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 22, Pages: 130-136, ISSN: 1053-2498
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- Citations: 16
Collet JP, Montalescot G, Fine E, et al., 2003, Enoxaparin in unstable angina patients who would have been excluded from randomized pivotal trials, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 41, Pages: 8-14, ISSN: 0735-1097
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- Citations: 54
Dalby M, Montalescot G, 2002, Transfer for primary angioplasty: who and how?, HEART, Vol: 88, Pages: 570-572, ISSN: 1355-6037
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- Citations: 4
Choussat R, Collet JP, Dalby M, et al., 2002, Low molecular weight heparin use in percutaneous coronary intervention., Crit Pathw Cardiol, Vol: 1, Pages: 180-183
Dalby MC, Davidson SJ, Burman JF, et al., 2002, Abciximab is rapidly effective in preventing and arresting established platelet aggregation, JOURNAL OF THROMBOSIS AND THROMBOLYSIS, Vol: 13, Pages: 141-145, ISSN: 0929-5305
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- Citations: 3
Dalby MCD, Schilling RJ, 2002, Lesson of the issue: Transection, migration and recovery of a peel-away introducer sheath during permanent pacemaker implantation, EUROPACE, Vol: 4, Pages: 159-160, ISSN: 1099-5129
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- Citations: 2
Dalby MCD, Davidson SJ, Burman JF, et al., 2002, Systemic platelet effects of contrast media: implications for cardiologic research and clinical practice., Am Heart J, Vol: 143
BACKGROUND: Angiographic contrast media cause platelet activation and decrease aggregability in vitro. We have previously shown in vitro a significant antiplatelet effect of contrast media at the concentrations obtained locally in the coronary artery during angioplasty. It is not known, however, whether a systemic effect is present. METHOD: Thirty patients undergoing diagnostic coronary angiography were prospectively randomized to receive the nonionic medium iohexol, ionic low-molecular-weight medium ioxaglate, or ionic high-molecular-weight medium diatrizoate. Platelet aggregability was measured before and after the investigation with whole blood electrical impedance aggregometry (WBEA) with collagen agonist and the PFA-100 (Dade, Miami, Fla) platelet function analyzer with combined shear, collagen, and adenosine diphosphate as agonists. RESULTS: With WBEA, with iohexol no difference in impedance change was seen: (medians and ranges) before, 9.8 Omega (4.8-19.2 Omega) versus after, 9.6 Omega (2-19.2 Omega) (P not significant [NS]). With ioxaglate a significant fall was seen: before, 8.6 Omega (6.4-15.2 Omega) versus after, 6.6 Omega (0-12.4 Omega) (P =.004). With diatrizoate a significant and greater fall was seen: before, 10.8 Omega (6.4-17.6 Omega) versus after, 6.6 Omega (0-10.8 Omega) (P =.002). With PFA, no difference in closure time was seen with any medium: iohexol before, 99 seconds (79-142 seconds) versus after, 142 seconds (63-128 seconds) (P NS); ioxaglate before, 120 seconds (75-258 seconds) versus after, 95 seconds (74-258 seconds) (P NS); and diatrizoate before, 114.5 seconds (65-250 seconds) versus after, 100.5 seconds (72-300 seconds) (P NS). CONCLUSIONS: Ionic but not nonionic contrast media have a systemic antiplatelet effect at diagnostic angiographic doses when measured with WBEA. Such an effect has not been shown before. This may explain the observed improved clinical outcome with ionic contrast media but also might confound platelet studies in
Dalby MCD, Burke M, Radley-Smith R, et al., 2001, Pheochromocytoma presenting after cardiac transplantation for dilated cardiomyopathy, JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 20, Pages: 773-775, ISSN: 1053-2498
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- Citations: 29
Dalby MCD, Davidson SJ, Burman JF, et al., 2000, Diurnal variation in platelet aggregation with the PFA-100 platelet function analyser, PLATELETS, Vol: 11, Pages: 320-324, ISSN: 0953-7104
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- Citations: 59
Dalby MCD, Davidson SJ, Burman JF, et al., 1999, Diurnal variation in platalet aggregability measured with the PFA-100™ 'platelet function analyser, THROMBOSIS AND HAEMOSTASIS, Pages: 826-826, ISSN: 0340-6245
Dalby MCD, Davidson SJ, Burman JF, et al., 1999, Established platelet aggregation is arrested within seconds by abciximab: Possible implications for treatment of unstable angina, Heart, Vol: 81, ISSN: 1355-6037
Background: When given to patients with unstable angina prior to angiography +/- PTCA, abciximab improves outcome in the short term. This study sought to establish how quickly abciximab blocks the aggregation of quiescent and activated platelets to investigate the likely speed of action of the agent when used in acute unstable angina. Methods: Platelet rich plasma was prepared from 10 healthy volunteers and optical aggregometry was performed with ADP 10μM/ml agonist. Abciximab 5μg/ml was added in each case with saline control 5 minutes before agonist, 10 seconds before agonist and during aggregation. Results: In all 10 cases abciximab administered 5 minutes before agonist completely inhibited aggregation (median=0% range=0-0%) compared with control (median=11% range=50-95%) p< 0.001. When administered 10s before agonist a small initial degree of aggregation occurred but this was rapidly reversed (time to reversal: median=2mins range=1.0-4.5mins) to low levels of aggregation (median=16.5% range=0-22%) when compared with control (median=72.5% range=55-95%) p=0.002. When administered during aggregation, in all cases the rise in the aggregometry tracing was rapidly arrested (time to arrest: median=1.5mins range=0.1-3.0mins) with no further aggregation occurring (median=42% range=30-57%) when compared with control (median=80% range=60-100%) p=0.002. These results have been confirmed with the independent method of whole blood impedance aggregometry. Conclusions: These data suggest that when administered to a patient with unstable angina in whom thrombus load has occurred, further aggregation is effectively stopped 'on the end of the needle'.
Dalby M, 1999, GP IIb/IIIa inhibitors: Additional cost or vital component in best practice? A round table discussion, Pages: 71-74, ISSN: 0969-6113
Antiplatelet therapy in cardiology is developing rapidly with the availability of potent platelet glycoprotein (GP) IIb/IIIa antagonists - effective but expensive drugs. There is currently a debate regarding how widely they should be used and their precise indications for usage, from both a medical and health economic standpoint. Miles Dalby reports on a round table discussion held at the Royal College of Physicians recently which addressed these issues. The meeting, sponsored with an educational grant from Eli Lilly, gathered representatives from cardiology, pharmacy, public health and health economics.
Dalby MCD, Dewar A, Davidson SJ, et al., 1999, Evaluation of angiographic contrast media and platelet function with impedance aggregometry and the PFA-100™ 'platelet function analyser', PLATELETS, Vol: 10, Pages: 293-297, ISSN: 0953-7104
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- Citations: 3
Purcell H, Dalby M, Sheppard M, et al., 1999, Unstable angina and its causes, Symposium on Key Advances in the Effective Management of Unstable Angina, Publisher: ROYAL SOC MEDICINE PRESS LTD, Pages: 1-5
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- Citations: 2
Dalby M, 1998, Acute coronary occlusion likely due to thrombus occurring during coronary angiography, CATHETERIZATION AND CARDIOVASCULAR DIAGNOSIS, Vol: 44, Pages: 459-459, ISSN: 0098-6569
Dalby M, 1998, The role of platelets and platelet inhibitors in acute coronary syndromes, Pages: 481-485, ISSN: 0969-6113
Dalby M, 1997, Platelet function and vessel wall passivation: The role of antiplatelet inhibitors in managing coronary syndromes, Pages: 346-348, ISSN: 0969-6113
PEPIN J, DALBY M, GAYE I, et al., 1991, LONG-TERM FOLLOW-UP OF SUBJECTS WITH AN INDETERMINATE HIV-2 WESTERN-BLOT, AIDS, Vol: 5, Pages: 1274-1275, ISSN: 0269-9370
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- Citations: 1
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