Imperial College London

Dr Nick Brooks

Faculty of Natural SciencesDepartment of Chemistry

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 2677n.brooks Website

 
 
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Location

 

207JMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Chan:2016:10.1039/C6LC01219A,
author = {Chan, CL and Bolognesi, G and Bhandarkar, A and Friddin, M and Brooks, NJ and Seddon, J and Law, R and Barter, L and Ces},
doi = {10.1039/C6LC01219A},
journal = {Lab on a Chip},
pages = {4621--4627},
title = {DROPLAY: laser writing of functional patterns within biological microdroplet displays},
url = {http://dx.doi.org/10.1039/C6LC01219A},
volume = {16},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - In this study, we introduce an optofluidic method for the rapid construction of large-area cell-sized droplet assemblieswith user-defined re-writable two-dimensional patterns of functional droplets. Light responsive water-in-oil dropletscapable of releasing fluorescent dye molecules upon exposure were generated and self-assembled into arrays in amicrofluidic device. This biological architecture was exploited by the scanning laser of a confocal microscope to ‘write’ userdefined patterns of differentiated (fluorescent) droplets in a network of originally undifferentiated (non-fluorescent)droplets. As a result, long lasting images were produced on a droplet fabric with droplets acting as pixels of a biologicalmonitor, which can be erased and re-written on-demand. Regio-specific light-induced droplet differentiation within a largepopulation of droplets provides a new paradigm for the rapid construction of bio-synthetic systems with potential as tissuemimics and biological display materials.
AU - Chan,CL
AU - Bolognesi,G
AU - Bhandarkar,A
AU - Friddin,M
AU - Brooks,NJ
AU - Seddon,J
AU - Law,R
AU - Barter,L
AU - Ces
DO - 10.1039/C6LC01219A
EP - 4627
PY - 2016///
SN - 1473-0197
SP - 4621
TI - DROPLAY: laser writing of functional patterns within biological microdroplet displays
T2 - Lab on a Chip
UR - http://dx.doi.org/10.1039/C6LC01219A
UR - http://hdl.handle.net/10044/1/41815
VL - 16
ER -