Summary
I am a Sir Henry Dale fellow in the Bacterial Evolutionary Epidemiology group at the MRC Centre for Global Infectious Disease Analysis, near Paddington. My work focusses on the biology of multi-strain bacterial populations, primarily Streptococcus pneumoniae (the pneumococcus). Such microbes often vary extensively in characteristics such as antibiotic resistance, virulence and expression of antigens that are potential vaccine targets. To understand this variation, my research encompasses laboratory molecular microbiology, analysis of genomic datasets, and computational modelling. Repeated emails are the best way to contact me.
Publications
Journals
Belman S, Pesonen H, Croucher NJ, et al., 2024, Estimating Between Country Migration in Pneumococcal Populations., G3 (bethesda)
Croucher NJ, 2024, Immune interface interference vaccines: An evolution-informed approach to anti-bacterial vaccine design., Microb Biotechnol, Vol:17
Croucher NJ, Campo JJ, Le TQ, et al., 2024, Genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci, Nature Communications, Vol:15, ISSN:2041-1723
Kwun MJ, Ion A, Oggioni MR, et al., 2023, Diverse regulatory pathways modulate bet hedging of competence induction in epigenetically-differentiated phase variants of Streptococcus pneumoniae, Nucleic Acids Research, ISSN:0305-1048
Horsfield ST, Tonkin-Hill G, Croucher NJ, et al., 2023, Accurate and fast graph-based pangenome annotation and clustering with ggCaller., Genome Res, Vol:33, Pages:1622-1637